Photo by Cindy Keese
All hotels in Seneca, South Carolina
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
All hotels in Seneca, South Carolina
We have found 1528 Seneca Hotels
- Hampton Inn & Suites Seneca-Clemson Area
- Boutique hotel in historic downtown Seneca. Room #2 Owners Suite. Q/K combo.
- Enchanting Historical1906 Modern Farmhouse: Perfect Blend of History and Comfort
- Tucker Farm Cottage on Century Farm
- Boutique hotel in historic downtown Seneca. Room#1, Q/K combo.
- The Inn at Patrick Square
- The Abernathy of Clemson
- Horizon Inn & Suites
- Home2 Suites by Hilton Anderson Downtown
- Hampton Inn Anderson/ Alliance Business Park
- Days Inn by Wyndham Lavonia
- Quality Inn
- Hampton Inn Hartwell
- Super 8 by Wyndham Lavonia
- Holiday Inn Express Hotel & Suites Lavonia, an IHG Hotel
- Hampton Inn Anderson
- Liberty Hall Bed and Breakfast
- Jewel of the Woods - Magnificent Views from an Incredible Lodge!
- Holiday Inn Express Anderson, an IHG Hotel
- Americas Best Value Inn Anderson, SC
- Windy Hill Lodge, A LUXURIOUS ESTATE
- BEAUTIFUL Newly Built Retreat w/Private Marina Boat Slip at Upper Lake Keowee!!!
- Residence Inn by Marriott Anderson Clemson
- My Home & Suites Toccoa
- Econo Lodge
- Hartwell Suites
- Historic B&B with delicious meals in charming Anderson
- Moments Happen Here: 10 acres
- Charming 1850 antebellum B&B, minutes from Anderson University and Clemson.
- BEAUTIFUL GUEST HOUSE NEAR THE SMOKEY MOUNTAINS
- Horse Cove Haven, Charming, Woodsy Retreat
Let Expedia take you to the best Hotels in Seneca. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.