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Top hotels and accommodation in Big Pine Key

Parmer's Resort

2.5 star property
8.8 out of 10, Excellent, (1002)
"One of the BEST stays in a hotel/resort I have had in a long time. Absolutely perfect! Both check in and check out hosts were amazing, room was VERY clean and comfortable, grounds were clean, peaceful and the beach on the property gave great views. Any time I come down, this will be my choice for stays!"
The price is AU$237
includes taxes & fees
4 Dec - 5 Dec
Parmer's Resort

Old Wooden Bridge Resort and Marina

2.5 star property
8.4 out of 10, Very good, (161)
"The houseboat was a delight. Super comfortable and a full kitchen. Very dog-friendly. The woman who checked us in was super nice, and the salt-water pool felt great!"
The price is AU$377
includes taxes & fees
24 Nov - 25 Nov
Old Wooden Bridge Resort and Marina

Sugarloaf Key Hotel at KOA Resort

3.0 star property
9.8 out of 10, Exceptional, (268)
"Beautiful Beautiful place "
Sugarloaf Key Hotel at KOA Resort

Sugar Loaf Lodge

2.5 star property
8.0 out of 10, Very good, (1020)
"Quiet hotel, convenient location, laid back! Helpful staff. However, Hotels.com com charged me than the existing rate at the hotel."
The price is AU$206
includes taxes & fees
24 Nov - 25 Nov
Sugar Loaf Lodge

Looe Key Reef Resort

2.5 star property
7.4 out of 10, Good, (1019)
"Great place to stay in the Keys."
The price is AU$210
includes taxes & fees
2 Dec - 3 Dec
Looe Key Reef Resort

Little Palm Island Resort & Spa - A Noble House Resort

5.0 star property
9.8 out of 10, Exceptional, (42)
"fabulous accommodation and staff...service is superb"
Little Palm Island Resort & Spa - A Noble House Resort

Barnacle Bed and Breakfast

3.0 star property
8.2 out of 10, Very good, (16)
"The location of the property was great and we saw the key deer on property and nearby. The room and bathroom were very nicely decorated and clean. The bed was comfortable. The beach front area had some trash that needed to be picked up and the home could use some landscaping. We did not stay for the continental breakfast so can not speak to that. Check in was a little challenging; I did not receive the e-mail day before check-in that I was expecting but did receive a phone call. However,...
The price is AU$481
includes taxes & fees
17 Dec - 18 Dec
Barnacle Bed and Breakfast

Areca Palms Cudjoe Key, Florida RV Concrete Pad only No Rooms or Bathrooms

10.0 out of 10, Exceptional, (1)
"Great RV spot in Cudjoe Key. Private, Secure great pool and great host. "
The price is AU$181
includes taxes & fees
24 Nov - 25 Nov
Areca Palms Cudjoe Key, Florida RV Concrete Pad only No Rooms or Bathrooms

Endless Summer Hideaway - lot 181

The price is AU$469
includes taxes & fees
30 Nov - 1 Dec
Endless Summer Hideaway - lot 181

Cozy 1-bedroom apartment with WiFi, AC in charming Cudjoe Key large outdoor

2.0 star property
The price is AU$188
includes taxes & fees
27 Nov - 28 Nov
Cozy 1-bedroom apartment with WiFi, AC in charming Cudjoe Key large outdoor

Tropical Caribbean Wonderland

9.2 out of 10, Wonderful, (77)
"The camper was clean and easy to find. There’s a bath/shower house 2campsites away. We enjoyed our stay."
Tropical Caribbean Wonderland

Tropical Florida Keys Resort with Boat Dock + pickleball, Pool and more!

10.0 out of 10, Exceptional, (1)
"Very cute little house. We had everything we needed for the 2 of us."
Tropical Florida Keys Resort with Boat Dock + pickleball, Pool and more!

85 Canalfront Empty RV Lot with 35' Seawall

2.0 star property
85 Canalfront Empty RV Lot with 35' Seawall

Tropical Getaway in Paradise.

9.4 out of 10, Exceptional, (83)
"Venture Out resort is nice and this cozy trailer is good!"
Tropical Getaway in Paradise.

Endless Ocean Views - RV589

The price is AU$519
includes taxes & fees
24 Nov - 25 Nov
Endless Ocean Views - RV589

Little Torch Cottages

2.0 star property
8.4 out of 10, Very good, (5)
"Great"
Little Torch Cottages

432 Empty Canalfront RV Lot with 32' Seawall

1.0 star property
432 Empty Canalfront RV Lot with 32' Seawall

Keys 3 Bedroom Corner Home near Beach & Key West

9.6 out of 10, Exceptional, (4)
"Great location, right in the middle keys, easy access to everything. "
The price is AU$956
includes taxes & fees
24 Nov - 25 Nov
Keys 3 Bedroom Corner Home near Beach & Key West

Gated Community on Open Water with Dock, Heated Pool, Kayaks, Bikes

9.8 out of 10, Exceptional, (216)
"Property was clean and had everything to have an enjoyable stay."
The price is AU$1,115
includes taxes & fees
24 Nov - 25 Nov
Gated Community on Open Water with Dock, Heated Pool, Kayaks, Bikes

Venture Out RV lot 223

The price is AU$379
includes taxes & fees
1 Dec - 2 Dec
Venture Out RV lot 223
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Beautiful view of the beach with palm trees

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Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

What are some of the best holiday rentals that Big Pine Key has to offer?

Aqua Lodge Rentals At Coconut Cay: This holiday home rental outside of Big Pine Key is located near the beach, and offers an outdoor pool, air conditioning and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a full-sized fridge, a stovetop and a microwave. Another good choice for your trip to Big Pine Key is Tropical Caribbean Wonderland. See all vacation rentals in Big Pine Key.

If I need to cancel my hotel reservation in Big Pine Key, will I receive a refund?

Yes, the majority of hotel reservations are refundable if you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Big Pine Key.

What's the best place to stay on a budget in Big Pine Key?

Based on reviews, Old Wooden Bridge Marina is a popular 2.5-star cottage for our travellers looking for an economical choice, and features free WiFi and free parking.

What's the best place to stay for a family trip to Big Pine Key?

Old Wooden Bridge Marina is a cottage with an outdoor pool and in-room kitchens, and it's a top choice on Expedia for families. Also, attractions in the area such as Island Hoppers Aerial Adventures and Crane Point Museum and Nature Center are fun for children of all ages.

What's the best dog-friendly place to stay in Big Pine Key?

Ocean View Room Barnacle bed and breakfast is a top guest house for people travelling with their pets and offers in-room balconies for its human guests. Ocean Depth Room Barnacle bed and breakfast Suite is another good choice for you and your pet. See more pet-friendly hotel accommodations in Big Pine Key.

What's the best hotel to stay near the beach in Big Pine Key?

Barnacle Bed and Breakfast is a top beachfront B&B offering free breakfast and free WiFi, located within a short 1-minute walk of Florida Keys Beaches . Deer Run Bed & Breakfast is another good option for your beach trip. See more stays near the beach in Big Pine Key.

What are some accommodation options with pools in Big Pine Key?

Old Wooden Bridge Resort and Marina: Features free self parking, an outdoor pool and complimentary wireless Internet access. Tropical Caribbean Wonderland and Isla Bella Beach Resort & Spa are a couple of other choices that feature an on-site pool. View all hotels with pools in Big Pine Key.

What is the best spa hotel in Big Pine Key?

Barnacle Bed and Breakfast is a top beach spa hotel with a rooftop terrace. Kick back and relax in the hot tub. Another popular spa hotel in Big Pine Key is Deer Run Bed & Breakfast. See all spa hotels in Big Pine Key.

How is it to stay in Big Pine Key?

Visitors can enjoy all that Big Pine Key has to offer, including its beaches. In Big Pine Key, there are 152 hotels and other accommodation options to choose from. Find out more about Big Pine Key.

What should I see while I'm in Big Pine Key?

Favorite family attractions include Blue Hole and Big Munson Island. Natural beauty is on display at Calusa Beach, Bahia Honda State Park and Florida Keys Beaches. A couple of additional sights to add to your itinerary are Big Pine Key Flea Market and Cook Island. Take a look at what more there is to see and do in Expedia's Big Pine Key guide.

What's the seasonal weather in Big Pine Key?

The hottest months are usually August and July, with an average temperature of 29°C, while the coldest months are January and February, with an average of 22°C. Average annual precipitation for Big Pine Key is 920 mm.