Photo by Molly Bond

Spa Hotels & Resorts in Clarksdale from AU$114

  • Plan, book, stay with confidence
    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Best Clarksdale Spa Hotels

Auberge Clarksdale Blues Hostel
City Single Room

Auberge Clarksdale Blues Hostel

2.0 star property
9.6 out of 10, Exceptional, (69)
"The staff was very friendly, making sure our experience was great. They offered recommendations and provided us with maps and entertainment schedules of upcoming live performances. "
The price is AU$171
includes taxes & fees
5 Dec - 6 Dec
Auberge Clarksdale Blues Hostel
Hampton Inn Clarksdale
Reception

Hampton Inn Clarksdale

2.5 star property
8.4 out of 10, Very good, (243)
"Good place to stay."
The price is AU$227
includes taxes & fees
7 Dec - 8 Dec
Hampton Inn Clarksdale
Quality Inn
Lobby sitting area

Quality Inn

2.5 star property
7.2 out of 10, Good, (630)
"Nothing unique but it was nice "
The price is AU$140
includes taxes & fees
8 Dec - 9 Dec
Quality Inn
Americas Best Value Inn & Suites Clarksdale
Lobby

Americas Best Value Inn & Suites Clarksdale

2.5 star property
5.8 out of 10, (328)
"It was a great visit. The Receptionist was very nice and friendly."
The price is AU$114
includes taxes & fees
26 Nov - 27 Nov
Americas Best Value Inn & Suites Clarksdale
The Sunflower Penthouse on the River in Clarksdale
Property grounds

The Sunflower Penthouse on the River in Clarksdale

10.0 out of 10, Exceptional, (12)
"A very quaint and quite place that says leave your troubles and worries behind. This place is for fun and quite relaxation!!!!"
The price is AU$368
includes taxes & fees
18 Dec - 19 Dec
The Sunflower Penthouse on the River in Clarksdale
Sunflower Suite on the River
Smart TV, fireplace, books

Sunflower Suite on the River

10.0 out of 10, Exceptional, (9)
"Beautiful, clean and very comfortable. We loved our stay at this property."
The price is AU$368
includes taxes & fees
1 Dec - 2 Dec
Sunflower Suite on the River
Dream Home in the MS Delta, home of the blues. 2 miles to all historical sites.
Fridge, microwave, oven, stovetop

Dream Home in the MS Delta, home of the blues. 2 miles to all historical sites.

10.0 out of 10, Exceptional, (1)
"This is a very clean, good, well equipped place to stay. A big plus is plenty of towels. A few extra blankets would be nice. We just turned the heat up so no problem. I would stay here again."
The price is AU$583
includes taxes & fees
26 Nov - 27 Nov
Dream Home in the MS Delta, home of the blues. 2 miles to all historical sites.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Clarksdale
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.
Unlock Black Friday deals

Frequently asked questions

Looking for a spa hotel in Clarksdale?
Forget the stress of everyday life and book yourself a hotel with a spa. Enjoy the live music scene and shops in Clarksdale—your day trip starts here. Enjoy the entertainment choices and many popular restaurants during your holiday. Hotels with spas are the perfect way to break away from your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Clarksdale?
Americas Best Value Inn & Suites Clarksdale is a top spa hotel with 50 rooms, free WiFi and laundry facilities. Enjoy a massage at the on-site spa.
How many spa hotels will I find in Clarksdale?
Among Expedia’s 18 accommodation options in Clarksdale, there is 1 spa hotel.
What's there to see and do in Clarksdale?
Enjoy Clarksdale with a stop at Delta Blues Museum, Red’s Lounge and Rock and Blues Museum. If you have extra time while you’re in the area, you might want to stop by Hambone Art Gallery and Mississippi River.
What is a Clarksdale spa hotel?
Spa hotels in Clarksdale provide lodging and have an on-site spa offering services including couples massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.