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Top hotels and accommodation in Defiance

Holiday Inn Express & Suites Wentzville St Louis West, an IHG Hotel
2.5 star property
9.4 out of 10, Exceptional, (676)
"No issues with check in. Good breakfast for hotel breakfast overall cleanliness good, some dust in higher places in room. Easy access toany restaurants and stores many walkable"
The price is AU$212
includes taxes & fees
24 Nov - 25 Nov
Holiday Inn Express & Suites Wentzville St Louis West, an IHG Hotel
Baymont by Wyndham Warrenton
2.5 star property
7.2 out of 10, Good, (879)
"Check was quick and easy, the staff was polite and professional. Overall nice hotel for the price"
The price is AU$134
includes taxes & fees
7 Dec - 8 Dec
Baymont by Wyndham Warrenton
Quality Inn
2.5 star property
8.2 out of 10, Very good, (682)
"Very friendly and clean, nice people good value"
The price is AU$139
includes taxes & fees
22 Dec - 23 Dec
Quality Inn
Economy Inn Wentzville
2.0 star property
6.4 out of 10, (394)
"All good "
The price is AU$122
includes taxes & fees
23 Nov - 24 Nov
Economy Inn Wentzville
Best Western Plus Washington Hotel
2.5 star property
9.0 out of 10, Wonderful, (507)
"The staff were very friendly, professional and helpful at check in. We are meeting up with other family members and the staff went out of their way to accommodate our group."
The price is AU$226
includes taxes & fees
1 Dec - 2 Dec
Best Western Plus Washington Hotel
Super 8 by Wyndham Warrenton
2.0 star property
7.4 out of 10, Good, (507)
"We stayed on the weekend of Diwali (the beginning of the Hindu fiscal year), so we understood the hotel was short staffed due to the celebration. On our 3rd attempt at a clean room, we got one. The woman working at check in was very kind. Later that evening when we returned, our TV didn't work. Another lady at the front desk came up and called the owner who walked her through fixing it. The room was clean, the beds were comfortable, and we slept well. The next morning my biggest issue was there...
The price is AU$102
includes taxes & fees
7 Dec - 8 Dec
Super 8 by Wyndham Warrenton
Fairfield Inn & Suites Wentzville
2.5 star property
9.0 out of 10, Wonderful, (542)
"The staff was very helpful. I had a family emergency and couldn't stay the following night. Booked through Expedia but the front desk person was helping me to resolve the issue."
The price is AU$241
includes taxes & fees
26 Nov - 27 Nov
Fairfield Inn & Suites Wentzville
Hampton Inn St. Louis Wentzville
2.5 star property
9.0 out of 10, Wonderful, (554)
"Very easy check in process. A lot of the parking was in front of the hotel which in my opinion is amazing. The young lady I dealt with during check in was very friendly and easy to work with. "
The price is AU$238
includes taxes & fees
5 Dec - 6 Dec
Hampton Inn St. Louis Wentzville
TownePlace Suites by Marriott Wentzville
3.0 star property
9.6 out of 10, Exceptional, (16)
"Very relaxing, clean, inviting, quiet and the staff were awesome!! Thank you!"
The price is AU$288
includes taxes & fees
24 Nov - 25 Nov
TownePlace Suites by Marriott Wentzville
Holiday Inn Express Warrenton, an IHG Hotel
2.5 star property
9.2 out of 10, Wonderful, (471)
"Great location, friendly staff, quiet room, clean and comfortable bed. Hot, delicious breakfast."
The price is AU$203
includes taxes & fees
8 Dec - 9 Dec
Holiday Inn Express Warrenton, an IHG Hotel
Super 8 by Wyndham Washington
2.0 star property
8.4 out of 10, Very good, (598)
"Weird key issue- they stopped working when we went to breakfast. We didn’t check out yet but the card keys stopped working. Our friends had the same issue. "
The price is AU$146
includes taxes & fees
3 Dec - 4 Dec
Super 8 by Wyndham Washington
The Inn at Elijah McLeans
4.0 star property
9.2 out of 10, Wonderful, (99)
"Very clean and customer service was great. We needed an early check in and they made it happen for us!"
The price is AU$236
includes taxes & fees
24 Nov - 25 Nov
The Inn at Elijah McLeans
Central Hotel
3.5 star property
9.8 out of 10, Exceptional, (102)
"We really enjoyed our stay. "
The price is AU$260
includes taxes & fees
23 Nov - 24 Nov
Central Hotel
Pinckney Bend Bed & Breakfast
3.0 star property
9.6 out of 10, Exceptional, (98)
"The breakfast was wonderful and view was tremendous. "
The price is AU$246
includes taxes & fees
8 Dec - 9 Dec
Pinckney Bend Bed & Breakfast
TheOutPostInn Bed&Breakfast - The Blue Victorian
10.0 out of 10, Exceptional, (3)
"Place was clean "
The price is AU$286
includes taxes & fees
23 Nov - 24 Nov
TheOutPostInn Bed&Breakfast - The Blue Victorian
Wine Haus: charming cottage with breathtaking views of the Missouri River!!
2.0 star property
10.0 out of 10, Exceptional, (1)
"Lived the scenery and decor. Hosts were lovely!! Vern nice breakfast!!"
The price is AU$307
includes taxes & fees
8 Dec - 9 Dec
Wine Haus: charming cottage with breathtaking views of the Missouri River!!
Private entry, lower area only with gameRoom, living room, bedroom and bathroom.
10.0 out of 10, Exceptional, (2)
"Not much available for cooking but we made it work. Boiled crab legs n baked biscuits on the grill! Beautiful weekend with the snow storm and views"
Private entry, lower area only with gameRoom, living room, bedroom and bathroom.
Lakefront Studio Condo
2.0 star property
10.0 out of 10, Exceptional, (6)
"Very cute condo it maximizes the space well, in addition the view is awesome! Highly recommend to anyone thinking of staying here"
The price is AU$406
includes taxes & fees
24 Nov - 25 Nov
Lakefront Studio Condo
TheOutPostInn Bed&Breakfast - The Purple Victorian
6.0 out of 10, (1)
"It was a small room and had to squeeze between the bed and wall to get in. Almost had to use the foot stool to get in the bed secondary to being so high up and the mattress was extremely firm. The pillows were super soft which did not go with the firm bed, woke up several times in the night to re fluff the pillows and still woke up with a sore neck. The thing that bothered me the most was the curtain in the bathroom was screwed to the wall and you could not close them for privacy. The building...
The price is AU$317
includes taxes & fees
23 Nov - 24 Nov
TheOutPostInn Bed&Breakfast - The Purple Victorian
Fish Haus: charming cottage with breathtaking views of the Missouri River!!
10.0 out of 10, Exceptional, (4)
"Everything was great. The hot breakfast and friendliness of the hosts were great. The view of the Missouri River was breathtaking."
The price is AU$307
includes taxes & fees
8 Dec - 9 Dec
Fish Haus: charming cottage with breathtaking views of the Missouri River!!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place to stay in Defiance?

Hollywood Casino & Hotel St. Louis, located 18.1 mi (29.2 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are La Quinta Inn & Suites by Wyndham St. Louis Westport and Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham. See all available top hotels, or vacation rentals in Defiance.

What are some of the best holiday rentals that Defiance has to offer?

The robin nest a cozy cottage on historic main street; pet Friendly: This holiday home rental outside of Defiance is equipped with a selection of games, air conditioning and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a fridge and a stovetop. See all vacation rentals in Defiance.

If I need to cancel my hotel reservation in Defiance, will I receive a refund?

Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.

What are some accommodation options with pools in Defiance?

La Quinta Inn & Suites by Wyndham St. Louis Westport: Offers free self parking, an outdoor pool and complimentary wireless Internet access. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham and The Wildwood Hotel are two additional hotels with an on-site pool. View all hotels with pools in Defiance.

How is it staying in Defiance?

Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station and Enterprise Center. In Defiance, there are 20 hotels and other accommodation options to choose from. Find out more about Defiance.

What should I do while I'm visiting Defiance?

Natural beauty is on display at August A. Busch Memorial Conservation Area, Broemmelsiek Park and Missouri River. A couple of additional sights to add to your itinerary are Chandler Hill Vineyards and Sugar Creek Winery. Take a look at what more there is to see and do in Expedia's Defiance guide.

What's the weather like in Defiance?

The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.