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4 Nov - 5 Nov
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5 Nov - 6 Nov
This weekend
8 Nov - 10 Nov
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15 Nov - 17 Nov

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Top hotels and accommodation in Defiance

Holiday Inn Express & Suites Wentzville St Louis West, an IHG Hotel
Exterior
Holiday Inn Express & Suites Wentzville St Louis West, an IHG Hotel
2.5 star property
9.4 out of 10, Exceptional, (670)
"Great location. The room was very spacious and clean. The staff at check-in was friendly. I really enjoyed my stsy. "
The price is AU$217
includes taxes & fees
17 Nov - 18 Nov
Holiday Inn Express & Suites Wentzville St Louis West, an IHG Hotel
Baymont by Wyndham Warrenton
Exterior
Baymont by Wyndham Warrenton
2.5 star property
7.2 out of 10, Good, (872)
"The room was clean and comfortable. When dealing with staff they were pleasant."
The price is AU$134
includes taxes & fees
10 Nov - 11 Nov
Baymont by Wyndham Warrenton
Quality Inn
Lobby
Quality Inn
2.5 star property
8.2 out of 10, Very good, (674)
"Very friendly and clean, nice people good value"
The price is AU$138
includes taxes & fees
19 Nov - 20 Nov
Quality Inn
Economy Inn Wentzville
Lobby
Economy Inn Wentzville
2.0 star property
6.4 out of 10, (392)
"Great inexpensive hotel. Comfortable beds and clean shower, its all we needed for a 1 night rest on the way thru. I didn’t see much for food nearby. "
The price is AU$121
includes taxes & fees
5 Nov - 6 Nov
Economy Inn Wentzville
Best Western Plus Washington Hotel
Lobby
Best Western Plus Washington Hotel
2.5 star property
9.0 out of 10, Wonderful, (504)
"Lady at front desk very helpful "
The price is AU$224
includes taxes & fees
10 Nov - 11 Nov
Best Western Plus Washington Hotel
Super 8 by Wyndham Warrenton
In-room safe, desk, laptop workspace, blackout curtains
Super 8 by Wyndham Warrenton
2.0 star property
7.4 out of 10, Good, (505)
"Robert was veey nice when we checked in at midnight. He was great at brealfast at 6. Clean, quiet rooom. Wonderful breakfast "
The price is AU$101
includes taxes & fees
10 Nov - 11 Nov
Super 8 by Wyndham Warrenton
Hampton Inn St. Louis Wentzville
Exterior
Hampton Inn St. Louis Wentzville
2.5 star property
9.0 out of 10, Wonderful, (552)
"There was nothing we didn't like. It was a great place to stay for 3 nights in Wentzville, Missouri!"
The price is AU$236
includes taxes & fees
17 Nov - 18 Nov
Hampton Inn St. Louis Wentzville
Fairfield Inn & Suites Wentzville
Reception
Fairfield Inn & Suites Wentzville
2.5 star property
9.0 out of 10, Wonderful, (541)
"Very clean rooms and a lot of food options close "
The price is AU$239
includes taxes & fees
11 Nov - 12 Nov
Fairfield Inn & Suites Wentzville
Super 8 by Wyndham Washington
Room, 2 Queen Beds, Non Smoking
Super 8 by Wyndham Washington
2.0 star property
8.4 out of 10, Very good, (596)
"We have stayed at a few Super 8's in our travels around this country, they are NOT our first choice by a long shot! but sometimes you don't have any other options, so I was a little Leary booking this one in Washington. MO., again not a lot of options, BUT we were pleasantly surprised! SAFE (no transients), CLEAN, FRIENDLY STAFF AND CONVIENENT to anything around the Washington area. "
The price is AU$143
includes taxes & fees
24 Nov - 25 Nov
Super 8 by Wyndham Washington
Holiday Inn Express Warrenton, an IHG Hotel
Lobby
Holiday Inn Express Warrenton, an IHG Hotel
2.5 star property
9.2 out of 10, Wonderful, (466)
"Clean, comfortable bed, friendly staff."
The price is AU$218
includes taxes & fees
2 Dec - 3 Dec
Holiday Inn Express Warrenton, an IHG Hotel
TownePlace Suites by Marriott Wentzville
In-room safe, desk, laptop workspace, blackout curtains
TownePlace Suites by Marriott Wentzville
3.0 star property
9.6 out of 10, Exceptional, (14)
"Very Clean, easy, no problems!"
The price is AU$286
includes taxes & fees
10 Nov - 11 Nov
TownePlace Suites by Marriott Wentzville
The Inn at Elijah McLeans
Balcony view
The Inn at Elijah McLeans
4.0 star property
9.2 out of 10, Wonderful, (98)
"The Inn itself is beautiful with a great view of river. The bed itself was so comfortable, but the pillows were too hard and flat. Would definitely come back!"
The price is AU$250
includes taxes & fees
5 Nov - 6 Nov
The Inn at Elijah McLeans
Central Hotel
Front of property
Central Hotel
3.5 star property
9.8 out of 10, Exceptional, (102)
"We really enjoyed our stay. "
The price is AU$258
includes taxes & fees
5 Nov - 6 Nov
Central Hotel
Pinckney Bend Bed & Breakfast
Property grounds
Pinckney Bend Bed & Breakfast
3.0 star property
9.4 out of 10, Exceptional, (96)
"Beautiful view and such a relaxing setting! Tricia and Tom were awesome hosts! Breakfast was delicious !"
The price is AU$242
includes taxes & fees
5 Nov - 6 Nov
Pinckney Bend Bed & Breakfast
Wine Haus: charming cottage with breathtaking views of the Missouri River!!
Bed sheets
Wine Haus: charming cottage with breathtaking views of the Missouri River!!
2.0 star property
10.0 out of 10, Exceptional, (1)
"Lived the scenery and decor. Hosts were lovely!! Vern nice breakfast!!"
The price is AU$301
includes taxes & fees
5 Nov - 6 Nov
Wine Haus: charming cottage with breathtaking views of the Missouri River!!
TheOutPostInn Bed&Breakfast - The Blue Victorian
Aerial view
TheOutPostInn Bed&Breakfast - The Blue Victorian
10.0 out of 10, Exceptional, (3)
"Place was clean "
The price is AU$285
includes taxes & fees
5 Nov - 6 Nov
TheOutPostInn Bed&Breakfast - The Blue Victorian
Fish Haus: charming cottage with breathtaking views of the Missouri River!!
Terrace/patio
Fish Haus: charming cottage with breathtaking views of the Missouri River!!
10.0 out of 10, Exceptional, (4)
"Everything was great. The hot breakfast and friendliness of the hosts were great. The view of the Missouri River was breathtaking."
The price is AU$301
includes taxes & fees
5 Nov - 6 Nov
Fish Haus: charming cottage with breathtaking views of the Missouri River!!
Private entry, lower area only with gameRoom, living room, bedroom and bathroom.
Terrace/patio
Private entry, lower area only with gameRoom, living room, bedroom and bathroom.
10.0 out of 10, Exceptional, (2)
"Not much available for cooking but we made it work. Boiled crab legs n baked biscuits on the grill! Beautiful weekend with the snow storm and views"
Private entry, lower area only with gameRoom, living room, bedroom and bathroom.
TheHistorian! Daniel Boone Country-Marthasville,MO
Interior
TheHistorian! Daniel Boone Country-Marthasville,MO
9.4 out of 10, Exceptional, (11)
"Lovely and comfortable place to stay"
The price is AU$316
includes taxes & fees
5 Nov - 6 Nov
TheHistorian! Daniel Boone Country-Marthasville,MO
Lakefront Studio Condo
Bar (on property)
Lakefront Studio Condo
2.0 star property
10.0 out of 10, Exceptional, (6)
"Very cute condo it maximizes the space well, in addition the view is awesome! Highly recommend to anyone thinking of staying here"
The price is AU$404
includes taxes & fees
5 Nov - 6 Nov
Lakefront Studio Condo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place to stay in Defiance?

Hollywood Casino & Hotel St. Louis, located 18.1 mi (29.2 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Sonesta ES Suites St. Louis - Chesterfield and La Quinta Inn & Suites by Wyndham St. Louis Westport. See all available top hotels, or vacation rentals in Defiance.

What are some of the best holiday rentals that Defiance has to offer?

The St. Charles Guest House, lovely historic home, fun for families and groups: This holiday home rental outside of Defiance is located on a river, and offers a fireplace, air conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. See all vacation rentals in Defiance.

If I need to cancel my hotel reservation in Defiance, will I receive a refund?

Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.

What are some accommodation options with pools in Defiance?

Sonesta ES Suites St. Louis - Chesterfield: Offers daily, a seasonal outdoor pool and free self parking. La Quinta Inn & Suites by Wyndham St. Louis Westport and The Wildwood Hotel are two additional hotels with an on-site pool. View all hotels with pools in Defiance.

How is it staying in Defiance?

Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station, Busch Stadium and Gateway Arch. In Defiance, there are 18 hotels and other accommodation options to choose from. Find out more about Defiance.

What should I do while I'm visiting Defiance?

Natural beauty is on display at Missouri River, August A. Busch Memorial Conservation Area and Broemmelsiek Park. A couple of additional sights to add to your itinerary are Chandler Hill Vineyards and Sugar Creek Winery. Take a look at what more there is to see and do in Expedia's Defiance guide.

What's the weather like in Defiance?

The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.