Holiday Homes in Depew

  • Plan, book, stay with confidence
  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Featured Holiday Homes in Depew

Beautiful furnished 2 bdr great location Elmwood

9.4 out of 10, Exceptional, (26)
"Great clean place close to everything! I’ll be back…"
Beautiful furnished 2 bdr great location Elmwood

Spacious Buffalo Home Near Niagara Falls/Bills Stadium

9.6 out of 10, Exceptional, (15)
"We were at this property for an NFL game . Location and other stores were very accessible easily. Our host was so easily accessible and helpful and made our stay amazing "
The price is AU$608
includes taxes & fees
26 Nov - 27 Nov
Spacious Buffalo Home Near Niagara Falls/Bills Stadium

Gorgeous Williamsville Home in Central Location

10.0 out of 10, Exceptional, (1)
"We enjoyed our stay. My brother in law had to have surgery so we drove up from Florida and rented this home for a week to be close for his recovery. Fantastic home with everything we needed. Loved the neighborhood was very quiet. Great backyard with a place to sit and enjoy the beautiful summer weather."
Gorgeous Williamsville Home in Central Location

Delightful, newly renovated, 3 bedroom cape in a charming country setting

2.0 star property
10.0 out of 10, Exceptional, (2)
"Really enjoyed our stay for the Bills game ! 6 adults had plenty of room to relax , house was well stocked! Sandy was a great host and communicator!"
Delightful, newly renovated, 3 bedroom cape in a charming country setting

4BR 1.5BA Electric Vehicle Charger~25min Falls

2.0 star property
2.0 out of 10, (1)
The price is AU$342
includes taxes & fees
26 Nov - 27 Nov
4BR 1.5BA Electric Vehicle Charger~25min Falls

4 bedrooms & 3 bathrooms | Entire Home For Families 🏠

9.6 out of 10, Exceptional, (40)
"Clean, Well Appointed and Comfortable. Exactly what we were looking for! "
The price is AU$508
includes taxes & fees
26 Nov - 27 Nov
4 bedrooms & 3 bathrooms | Entire Home For Families 🏠

No Chores, 10min downtown and 25 min Niagara falls

9.2 out of 10, Wonderful, (25)
"Very nice stay highly recommend "
The price is AU$345
includes taxes & fees
9 Dec - 10 Dec
No Chores, 10min downtown and 25 min Niagara falls

Magazine featured townhome steps from Elmwood Village 25mins from Niagara Falls

9.6 out of 10, Exceptional, (45)
"This property was amazing! Just as listed, super cozy/cute and clean property! Easy to highways and close to the Falls! Absolutely loved this place."
Magazine featured townhome steps from Elmwood Village 25mins from Niagara Falls

Buffalo Getaway w/ Charcoal Grill & Patio!

9.2 out of 10, Wonderful, (25)
"My family and I stay hear for the bills dolphins game. It was perfect. 1/2 hour away from stadia"
Buffalo Getaway w/ Charcoal Grill & Patio!

Cute n spacious Westbrook home very close to Buffalo Int Airport and everywhere!

2.0 star property
Cute n spacious Westbrook home very close to Buffalo Int Airport and everywhere!

Snug 1st Floor|25 Mins to Falls!

2.0 star property
The price is AU$293
includes taxes & fees
2 Dec - 3 Dec
Snug 1st Floor|25 Mins to Falls!

This spacious, pristine 3 bedroom retreat is ideal for families & larger groups

10.0 out of 10, Exceptional, (10)
"We were in town for a family wedding and this place was perfect for young kids and adults as well! Would highly recommend "
The price is AU$831
includes taxes & fees
26 Nov - 27 Nov
This spacious, pristine 3 bedroom retreat is ideal for families & larger groups

Adorable West Side Cottage w Free Onsite Parking!

9.6 out of 10, Exceptional, (10)
"Overall, this was a lovely place to stay. It's easy to find, and check-in/check-out was simple. It's in a beautiful part of town. I would stay here again. There are two things that kept me from giving a 5-star rating. First, parking was very cramped. Getting in was easy, but getting out takes some fancy footwork. If the little lawn area in front of the cabin was halved, so a car could pull further in, it would make backing up and turning around SO much easier. Second, the mattress and pillows...
Adorable West Side Cottage w Free Onsite Parking!

Clean Modern Home,Cozy MINUTES to Airport and Downtown

10.0 out of 10, Exceptional, (89)
"Nice quiet neighborhood. Home is very clean and adequately stocked with essentials for your stay. "
Clean Modern Home,Cozy MINUTES to Airport and Downtown

Newly Renovated, Charming Downtown Buffalo Home + Free Parking

9.6 out of 10, Exceptional, (47)
"My family was visiting Buffalo for our nephew's wedding. The reason we chose this house was the two bathrooms. It was a very nice stay in a beautiful home. My elderly parents stayed in the downstairs bedroom and used the downstairs bath. My family had the two bedrooms and bath upstairs. My pre-teen slept on the futon downstairs. The street was absolutely gorgeous with the fall colors. We felt safe in the neighborhood. The host was very responsive and fast with communication. I would...
Newly Renovated, Charming Downtown Buffalo Home + Free Parking

Live on the Lake! 3 Bdr, huge living room, fire pit, cabana, SUNSETS and FUN!

9.8 out of 10, Exceptional, (21)
"It was awesome! Nothing like a home on the lake. Host and experience was amazing. Will definitely stay again plus I have already told my friends about it. "
Live on the Lake! 3 Bdr, huge living room, fire pit, cabana, SUNSETS and FUN!

Entire Home 3 Bedroom 1 Bath 6 Guests - Convenient Location close to Airport

10.0 out of 10, Exceptional, (4)
"Great location and easy access to get around with a nice quiet neighborhood. Owners were very prompt with answering any questions we had."
Entire Home 3 Bedroom 1 Bath 6 Guests - Convenient Location close to Airport

Serene Buffalo Dwelling w/ Backyard BBQ Patio

8.2 out of 10, Very good, (10)
"Quiet, clean place that met our needs for a wedding and a family reunion. Beds are a bit firm, the bathroom is small, stairs to the front door are steep, and the TV didn’t have YouTubeTV. These are the only negatives I had. I’ll be using this location for future visits. "
Serene Buffalo Dwelling w/ Backyard BBQ Patio

Down Town Buffalo, 20 Minutes From The Niagara Falls

9.6 out of 10, Exceptional, (30)
"This property was very unique, we really loved our stay. It was just like if you’re in your own house having a great time resting. The only issue is the second floor neighbor he walks all night long and doesn’t let you rest. Very noisy both days of our stay until 3 am. "
The price is AU$307
includes taxes & fees
26 Nov - 27 Nov
Down Town Buffalo, 20 Minutes From The Niagara Falls

Brand new furniture with parking

10.0 out of 10, Exceptional, (3)
"The property was very nice and clean, and the owner, Sajjad, was wonderful. Would stay there again. VRBO however is terrible. Poor communication, hidden fees, and overall lousy organization. Just awful. "
The price is AU$391
includes taxes & fees
10 Dec - 11 Dec
Brand new furniture with parking
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Depew
Save an average of 15% on thousands of hotels when you're signed in

Other property types in Depew

Beautiful furnished 2 bdr great location Elmwood

9.4 out of 10, Exceptional, (26)
"Great clean place close to everything! I’ll be back…"
Beautiful furnished 2 bdr great location Elmwood

4 bedrooms & 3 bathrooms | Entire Home For Families 🏠

9.6 out of 10, Exceptional, (40)
"Clean, Well Appointed and Comfortable. Exactly what we were looking for! "
The price is AU$508
includes taxes & fees
26 Nov - 27 Nov
4 bedrooms & 3 bathrooms | Entire Home For Families 🏠

Spacious 1st Floor. Entire Apartment

7.4 out of 10, Good, (28)
"Good for budget stay for family "
The price is AU$188
includes taxes & fees
26 Nov - 27 Nov
Spacious 1st Floor. Entire Apartment
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.