
Eastern Panama Holidays from AU$858
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Your Eastern Panama Holiday
Leave all the planning to us with an Eastern Panama holiday package. With everything organised before you jet off, all you need to do is sit back, chill out and experience this destination's many wonders. Where to start your journey? In the most popular cities, of course. Isla Tigre and Palenque are two great places to kick off your itinerary during your trip to Eastern Panama. When it's time to stop daydreaming and start doing, Expedia will help turn your Eastern Panama holiday into reality.
The Latest Eastern Panama Holiday Deals
Price found within the past 48 hours. Click for updated prices.

MARINN Tropical Vibes Hotel
Amador
Price was AU$982, price is now AU$858 per person
AU$858
per person
5 Nov - 8 Nov
found 1 day ago
Return flight included
Medellín (MDE) to Panama City (PTY)
8.2/10 Very Good! (128 reviews)
This is an excellent little hotel not too far from the “city centre”. All stays include buffet breakfast (630-930am). Rooms were clean, spacious and had a great view of the ocean / marina. A/C, cable tv and WiFi were all standard (WiFi password & QR code are at the front desk). There is also no resort fee or “incidental hold” on my card. I simply walked in with my passport, signed the booking form and collected my keys.
There are small snacks and drinks available for purchase at the front desk. Credit card is widely accepted here (and across Panama in general). You’ll rarely find a “cash only” place. That being said, ATMs are abundant and they all spit out USD. Foreign cards are limited to $250usd per withdrawal but there’s nothing stopping you from doing more than 1 transaction.
The location is great for a simple stay. You have a great view of the ocean, the entire causeway has a walkway littered with a vast array of foods, snacks and adult dining. Transport to/from the area is a breeze. I’ve gotten Ubers in seconds because they’re always in the area. Cheap transport to places like Biomuseo, Bridge of Americas, Multiplaza Mall, Casco Viejo (<$10 but most averaged $2-4usd)
The front desk is versed in both English and Spanish and you can get by just fine if you know little to no Spanish.
My only issue was:
1. My room had only a fridge. No microwave. No coffeemaker
Reviewed on 15 Sept 2025

Central Hotel Panama Casco Viejo
Casco Viejo
Price was AU$1,787, price is now AU$1,279 per person
AU$1,279
per person
5 Nov - 8 Nov
found 1 day ago
Return flight included
Medellín (MDE) to Panama City (PTY)
9/10 Wonderful! (986 reviews)
The jacuzzi in the room was terrible. Many, many times I tried but could not get it to work. Maintenance came multiple times, but they too had a hard time getting it to work.
Reviewed on 9 Sept 2025

Megapolis Hotel Panamá
San Francisco
Price was AU$1,222, price is now AU$982 per person
AU$982
per person
5 Nov - 8 Nov
found 1 day ago
Return flight included
Medellín (MDE) to Panama City (PTY)
8.4/10 Very Good! (1,056 reviews)
Nice Staff, convenient, Excellent Breafast, need to be restored! I have visiting since was HRH
Reviewed on 14 Sept 2025

Eastern Panama Holiday
Eastern Panama Essential Information
Language | Spanish |
---|---|
Currency | Panamanian balboas |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Tocumen Intl. Airport (PTY) |
Top Sights | Portobelo National Park, Isla Mamey and Cayos Holandeses |
Our pick of the best Eastern Panama Hotel Deals

Hotel Cocotal
La Guaira, Isla Grande, Provincia de Colón
Fully refundableReserve now, pay when you stay
The price is AU$147 per night from 16 Sept to 17 Sept
AU$147
16 Sept - 17 Sept
includes taxes & fees
10/10 Exceptional! (2 reviews)
"It was old, quaint interesting, would recommend"
Reviewed on 5 Sept 2025

Ciel y Miel
Caillle Principale, Cacique, Provincia de Colón
10/10 Exceptional! (9 reviews)
"All was good"
Reviewed on 14 July 2025

Ordovician Beach Resort
Isla Grande, Isla Grande, Colon
10/10 Exceptional! (3 reviews)
"Amazing piece of Caribbean paradise! The staff went above and beyond to make us feel special."
Reviewed on 5 Sept 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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