Unique features of Historical Center include the mountain views and historical sites. Make a stop by Arequipa Plaza de Armas or Arequipa Cathedral while you're exploring the area.
While visiting Yanahuara, you might make a stop by sights like Yanahuara Plaza and Yanahuara Viewpoint.
Though José Luis Bustamante y Rivero may not have many top sights, you can venture to the surrounding area to see attractions like Mall Aventura Porongoche and Parque Lambramani.
You might consider checking out Museo de Arte Contemporaneo Arequipa while you're exploring Mariano Melgar and the larger Arequipa area.
While Cerro Colorado District isn't home to many top sights, Yanahuara Plaza and Monasterio de la Recoleta are some notable places to visit nearby.