Guana Tolomato Matanzas National Estuarine Research Reserve Tours and Activities
Visit Guana Tolomato Matanzas National Estuarine Research Reserve
Plan a trip to see Guana Tolomato Matanzas National Estuarine Research Reserve
![Beach Place Guesthouses](https://images.trvl-media.com/lodging/3000000/2990000/2985300/2985218/b2c632f9_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Beach Place Guesthouses
Reviewed on 25 Jan. 2025
![Harbor Island Beach Club by Villatel](https://images.trvl-media.com/lodging/92000000/91110000/91103400/91103347/8ca40509_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Tours & day trips
See all 125 activities![St Augustine Old Town Trolley Hop-on Hop-off City Tour](https://mediaim.expedia.com/localexpert/179839/012cfb63-4ec8-424e-9a36-7e5cbbf3bb9b.jpg?impolicy=resizecrop&rw=500&rh=280)
St Augustine Old Town Trolley Hop-on Hop-off City Tour
Food, drink & nightlife
See all 24 activities![St. Augustine: Treasure Hunt Cruise with Onboard Show](https://mediaim.expedia.com/localexpert/4511437/cd2fa1e7-fe13-4968-b2b8-21a605024238.jpg?impolicy=resizecrop&rw=500&rh=280)
St. Augustine: Treasure Hunt Cruise with Onboard Show
Private & custom tours
See all 22 activities![Arcimoto Electric Vehicle Adventure Rental in St. Augustine](https://mediaim.expedia.com/localexpert/46276246/3464fd29-7cf7-49e1-ac41-415ab9aa17f6.jpg?impolicy=resizecrop&rw=500&rh=280)
Arcimoto Electric Vehicle Adventure Rental in St. Augustine
Holiday & seasonal tours
See all 14 activities![St. Augustine: Tour Pass with over 27 Attractions](https://mediaim.expedia.com/localexpert/48275477/35bf87aa-0078-4aba-835e-8b42927946cd.jpg?impolicy=resizecrop&rw=500&rh=280)
St. Augustine: Tour Pass with over 27 Attractions
Water activities
See all 5 activities![St. Augustine: St. Johns River Airboat Safari with a Guide](https://mediaim.expedia.com/localexpert/47871058/c12e1458-01a0-407f-8590-f0c60921a6b7.jpg?impolicy=resizecrop&rw=500&rh=280)
St. Augustine: St. Johns River Airboat Safari with a Guide
Popular places to visit
![Fort Mose Historic State Park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/498000/498248-fort-mose-historic-state-park.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Fort Mose Historic State Park
Learn about the local history of St. Augustine with a stop at Fort Mose Historic State Park. Stroll along the area's beautiful beaches or experience its fascinating museums.
![Vilano Beach](https://mediaim.expedia.com/destination/1/4867b551c7e9995e506a8fc35f91d55a.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)
Vilano Beach
Why not spend a care-free afternoon at Vilano Beach during your travels in St. Augustine? Amble around this family-friendly area's seaside and enjoy its top-notch restaurants.
Guana Pine State Park and Wildlife Management Area
Explore the lovely green spaces of Guana Pine State Park and Wildlife Management Area and enjoy the golf courses in Ponte Vedra Beach. Wander the beautiful beaches and seaside in the area.
South Ponte Vedra Beach
Why not spend a lazy afternoon at South Ponte Vedra Beach during your trip to Ponte Vedra Beach?
Guana River Wildlife Management Area
You can take time to visit Guana River Wildlife Management Area during your travels to Ponte Vedra Beach.
Water + Stone Gallery
You can browse the exhibits at Water + Stone Gallery, a museum with a storied past, during your travels to St. Augustine. Wander the beautiful beaches and seaside in the area.
Top Guana Tolomato Matanzas National Estuarine Research Reserve Hotel & Accommodation Deals
Check availability on hotels close to Guana Tolomato Matanzas National Estuarine Research Reserve
![LUXURY BEACHFRONT MANSION 6 BEDROOM](https://images.trvl-media.com/lodging/64000000/63510000/63502300/63502260/075387b9_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
![Dolphin View | Wren Beach Rentals by Portoro](https://images.trvl-media.com/lodging/104000000/103420000/103412300/103412277/cf50c9c5_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
![Beachfront with Grill, Hammocks & Endless Views
Pet Friendly](https://images.trvl-media.com/lodging/74000000/73410000/73401200/73401175/7e05f17e_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
![New Ponte Vedra 9 bedroom Estate home!](https://images.trvl-media.com/lodging/68000000/67680000/67671200/67671175/2eef3276_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
![Seaside South Ponte Vedra Beach Haven](https://images.trvl-media.com/lodging/97000000/96450000/96443100/96443063/53c279f8_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
![Oceanfront House with Private Beach, Patio, and Gameroom](https://images.trvl-media.com/lodging/34000000/33280000/33276400/33276363/6b5a81fd_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
![The Great Escape Oceanfront on Ponte Vedra Beach!](https://images.trvl-media.com/lodging/37000000/36370000/36367800/36367771/c7f83c1b_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
![Wonderful Daytime Temps and Cool Pricing Blue Gem for January & February](https://images.trvl-media.com/lodging/102000000/101360000/101355900/101355899/d832adaf_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
![Beachfront house in Ponte Vedra Beach with beach views & deck](https://images.trvl-media.com/lodging/97000000/96400000/96393400/96393376/e4bc40c5_y.jpg?impolicy=fcrop&w=420&h=224&q=medium)
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