Isla Grande Holiday Rentals

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Holiday Rentals in Isla Grande

Brother Sun Villas

3.0 star property
3.0 out of 10, (2)
"This is where advertisement they told me that display have AC Wi-Fi TV and they don’t have to bring a lot of money for this room and he’s not worth it I wanted to cancel the second night and the lady didn’t want to return my money back I call hotels.com and complained about it and they didn’t do nothing about it and that even cackle back from them I will never book with thing again I don’t mind paying the money if the play is right"
Brother Sun Villas

Spacious Beach House on the ocean front with huge pool and patio.

8.4 out of 10, Very good, (5)
"A nice house with ocean view was proposed. We got a house with a huge orange wall right in front of the sea. No view. House was not clean. More than half of the lightbulbs were not working. Stove and oven not working. Could not open the bedroom access to the balcony, door was in bad shape and full of crap. Not at all what we have paid for. Owner should be honest and tell remote his house with the ugly wall blocking the view. We were stolen of our few first days of vacation. We had to go...
Spacious Beach House on the ocean front with huge pool and patio.

Alquiler vacacional en Playa Escondida and Marina /Descuento semanal/mensual

Alquiler vacacional en Playa Escondida and Marina /Descuento semanal/mensual

Casa Dinis - Loft - CON Vistas Bahia DE Portobelo

The price is AU$602
includes taxes & fees
30 Nov - 1 Dec
Casa Dinis - Loft - CON Vistas Bahia DE Portobelo

San Marino Duo, this is casa 36 - Book one or both Casa 36 & 37

9.0 out of 10, Wonderful, (4)
"Great views and a relaxing time was had at this comfortable sea side duplex. We were the only renters so we had the whole yard and pool to ourselves. Bob was an excellent resident owner host and the support staff of Maria and Ilariao were perfect and there when we needed help. Getting to Michi was an adventure especially at night and at the end of Mardi Gras...the road and the citizens were a challenge. After we got the lay of the land driving the area and meeting the residents of the Portobelo...
San Marino Duo, this is casa 36 - Book one or both Casa 36 & 37

Casa Frente al Mar - Isla Grande

10.0 out of 10, Exceptional, (1)
"All perfect "
Casa Frente al Mar - Isla Grande

Casa Anzuelo is an oceanfront home that is all about the water and nature.

10.0 out of 10, Exceptional, (14)
"Jim was a superb host and the accommodation is really nice with everything you need for a comfortable stay. The village is simple and friendly and the wildlife great - monkeys and sloths. The lagoon and reef outside the property is really interesting. Will stay again."
Casa Anzuelo is an oceanfront home that is all about the water and nature.

Caribbean Beach House with Pool

10.0 out of 10, Exceptional, (1)
"This property was well kept and managed, even with a few glitches the property owners were very responsive. It’s a peaceful environment we wouldn’t hesitate to visit again."
Caribbean Beach House with Pool

Paraiso de Ensueño Caribeño

10.0 out of 10, Exceptional, (2)
"If enjoy and appreciate nature this is a wonderful place. You have all the basics necessary for unforgettable stay. The local people are very nice and welcoming. The see is magnificent.! "
Paraiso de Ensueño Caribeño

Piscina Mar en el Paraíso Caribe

10.0 out of 10, Exceptional, (2)
"Muy tranquilo durante la semana. Muy amable en personal"
Piscina Mar en el Paraíso Caribe

BEAUTIFUL APARTMENT IN FRONT OF THE SEA

4.0 out of 10, (1)
"The furnishings are worn. The second bedroom is only suitable for small children. The house is only a few metres from a busy main road with noisy traffic. The beach is unattractive. The water is too shallow for swimming. And the house is NOT in the “historic centre” of Portobelo, which is several kilometres away and consists of the ruins of a fort and a church. We were so disappointed we left after one night."
BEAUTIFUL APARTMENT IN FRONT OF THE SEA

BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

10.0 out of 10, Exceptional, (29)
"A beautiful beachfront property with hammocks, snorkeling, kayaks and a lovely staff to prepare meals made this the ideal location for our family Christmas holiday."
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

A fantastic place between the sea and the jungle

10.0 out of 10, Exceptional, (4)
"La comunicación con los anfitriones siempre fue buena, siempre atentos, recibíamos respuesta inmediata a cualquier consulta. La atencion muy buena, Chente y Laura estaban atentos a todo lo que se necesitara. Lindas vistas y muy cómodas las cabañas. Recomendado!!"
A fantastic place between the sea and the jungle

Cara al mar Cacique

10.0 out of 10, Exceptional, (1)
"Rachel (the property owner) is the BEST! The car I rented couldn’t get up the steep driveway and she was there immediately to offer help. The views from the house are spectacular. We spent most of our time outside because there is a nice breeze off the ocean. I can hear howler monkeys. "
Cara al mar Cacique

Pebos Reef with amazing terrace over the sea - apartment #1

Pebos Reef with amazing terrace over the sea - apartment #1

Cabaña La Punta op het Strand!!

The price is AU$264
includes taxes & fees
3 Dec - 4 Dec
Cabaña La Punta op het Strand!!

Casa Dinis - Casa Grande - Centro DE Portobelo

The price is AU$934
includes taxes & fees
30 Nov - 1 Dec
Casa Dinis - Casa Grande - Centro DE Portobelo

Casa Dinis - Habitación - Centro DE Portobelo

The price is AU$211
includes taxes & fees
1 Dec - 2 Dec
Casa Dinis - Habitación - Centro DE Portobelo

HERMOSA Y COMODA CASA EN LAS COSTAS DEL MAR CARIBE<br><br>IN FRONT OF THE SEA

5.4 out of 10, (3)
"What a fantastic property! You could not ask for more if you plan to stay on the Caribbean side of Panama... Casa Buenaventura was perfect for our troop of 4 adults and 5 children. Clean, well appointed, lots of space... and Gabriel was the best! He met us personally upon check in to show the house, provide us with a full itinerary for 5 days of fun, beaches, private boat tour, short trips along the coast, snorkeling, and more! Additionally, Gabriel was only a quick What'sApp text away with any...
The price is AU$438
includes taxes & fees
2 Dec - 3 Dec
HERMOSA Y COMODA CASA EN LAS COSTAS DEL MAR CARIBE<br><br>IN FRONT OF THE SEA

Nice house in Portobelo, Skybluebyguanche

The price is AU$241
includes taxes & fees
30 Nov - 1 Dec
Nice house in Portobelo, Skybluebyguanche
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other types of properties in Isla Grande you may be interested in

Coconut Grove Lodge

2.5 star property
8.2 out of 10, Very good, (59)
"A very nice place for Panamanian standards. It’s obvious they are in the process of fixing things up but some things still need a little work. The room and beds were very comfortable. The complimentary breakfast and welcome beverage were outstanding. There is a small lagun to swim and snorkel in. Saw lots of small fish but the waves and break made it impossible to go very far. The facility is very isolated from the rest of the island which can be nice but also very isolated. The parking lot has...
Coconut Grove Lodge

Sister Moon Hotel

2.0 star property
6.6 out of 10, (4)
"The hotel is in a beautiful setting overlooking the ocean. The pool and deck are great to relax in and watch the waves. The restaurant food was good (need hour notice for dinner). The rooms are really rustic and ours did not have AC. Also, note that there is not a public beach on Isla Grande. We spent all day at Coconuts on the other side of island at their beach and would probably stay there if we went again. We were traveling with 2 teens. "
Sister Moon Hotel

Brother Sun Villas

3.0 star property
3.0 out of 10, (2)
"This is where advertisement they told me that display have AC Wi-Fi TV and they don’t have to bring a lot of money for this room and he’s not worth it I wanted to cancel the second night and the lady didn’t want to return my money back I call hotels.com and complained about it and they didn’t do nothing about it and that even cackle back from them I will never book with thing again I don’t mind paying the money if the play is right"
Brother Sun Villas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Beautiful view of the beach with palm trees

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Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

Can I find holiday rentals in Isla Grande?

Yes, there are holiday rentals close to the most popular sights in Isla Grande, or you can select a more secluded option if you're looking for a relaxing stay. Isla Grande is known for its parks.

What are some of the best holiday rentals that Isla Grande has to offer?

Brother Sun Villas: This highly rated holiday home rental in Isla Grande is located on the beach, and has an outdoor pool, a balcony and a BBQ to put you at ease in your new surroundings. Kitchen amenities include a full-sized fridge, a stovetop and a microwave. Kick off your shoes and enjoy yourself with a terrace and a garden.

How many holiday rentals will I find in Isla Grande?

With 3 Expedia holiday rentals, you're guaranteed to find just the right place for your Isla Grande stay.

What can I see and do in Isla Grande?

While you're exploring the area, Isla Mamey and Blanca Beach are a couple of picturesque spots to get outside and enjoy nature. In the wider area, you’ll find Portobelo National Park and San Felipe Church.

What are holiday rentals like in Isla Grande?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Isla Grande. Holiday rentals feature extras such as laundry facilities and kitchens so you'll have all the comforts of home. If you're concerned about a sanitised environment, a holiday rental can provide a sense of privacy away from shared hotel lifts and busy lobbies while still allowing you a great travel experience. You'll also get more space in a holiday rental than in a standard hotel, which makes a holiday rental a great choice for family trips or small group gatherings.