
Isolotto Holidays
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Your Isolotto Holiday
Reserving a tailor-made Isolotto holiday package is a good way to know the ins and outs of this unique neighbourhood. From its must-see spots to its lesser-known delights, there's a lot to delve into. When it's time to head out and explore, you'll find plenty of popular attractions nearby including Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Visit one, two or more during your trip to Isolotto. Stop dreaming and start doing. When it's time to book your next holiday to Isolotto, Expedia is here to help.
Our guide on where to stay in Isolotto

Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Uffizi Gallery while you're exploring the neighbourhood.
Our pick of the best Isolotto Hotel Deals

Reviewed on 8 Apr. 2025

Reviewed on 9 Apr. 2025

Reviewed on 10 Apr. 2025
Frequently asked questions
Discover the most popular places to visit in Isolotto

Historic Centre of Florence
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Piazza di Santa Maria Novella
After visiting Piazza di Santa Maria Novella, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or experience the fascinating museums in this vibrant area.

Cathedral of Santa Maria del Fiore
The magnificent dome of Santa Maria del Fiore provides the Florentine skyline with one of its most iconic outlines.
Activities

Cinque Terre and Pisa Day Trip from Florence

Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine
