Mesopotamia Holidays

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Your Mesopotamia Holiday

Known for its diversity and cultural experiences, Mesopotamia promises a truly unforgettable travel adventure. Book one of our Mesopotamia holiday packages and spend a few exciting weeks or more discovering all the cool things this destination has to offer. The best and easiest way to organise your trip to Mesopotamia is to start with its leading cities, which include Gualeguaychú, Parana and Colon. Find some travel buddies and start packing, because your Mesopotamia holiday is just clicks away with Expedia.

Mesopotamia Holiday

Mesopotamia Essential Information

Language
Spanish
Currency
Argentine pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Ministro Pistarini Intl. Airport (EZE)
Top Sights
Termas De Colón, Termas Del Ayui and Termas Concepcion Entrerios

Our pick of the best Mesopotamia Hotel Deals

Hathor Concordia
Hathor Concordia
3 out of 5
Ruta Nacional 14-km 264.5, Concordia, Entre Rios
Fully refundableReserve now, pay when you stay
The price is AU$120 per night from 12 Feb to 13 Feb
AU$120
includes taxes & fees
12 Feb - 13 Feb
8.6/10 Excellent! (333 reviews)
"Very clean room at affordable price. The dinning is of excellent quality at very reasonable price. The staff are quite friendly and helpful."

Reviewed on 31 Dec. 2024

Hathor Concordia
O2 Hotel Gualeguaychú
O2 Hotel Gualeguaychú
2.5 out of 5
115 3 de Febrero, Gualeguaychú, Entre Ríos
Fully refundableReserve now, pay when you stay
The price is AU$70 per night from 9 Feb to 10 Feb
AU$70
includes taxes & fees
9 Feb - 10 Feb
7.4/10 Good! (52 reviews)
"Hotel is very comfortable and clean. There is no breakfast or hotel parking, and the wifi does not work properly in most floors and rooms. Other than that, the staff is very friendly and nice."

Reviewed on 2 Jan. 2025

O2 Hotel Gualeguaychú
Totoras Apart Federacion
Totoras Apart Federacion
2.5 out of 5
Ñandubay (ex Hermanas Betancourt) 2610, Federacion, Entre Rios
The price is AU$93 per night from 11 Feb to 12 Feb
AU$93
includes taxes & fees
11 Feb - 12 Feb
7.2/10 Good! (25 reviews)
"Buena estadia para unos dias .todo muy limpio a pesar de que estan aun terminando dptos.tal vez deben cuidar más los horarios de descanso del turista con los ruidos de la obra . Pocos utensilios de cocina si se quiere cocinar ahi mismo.Pero tranquilo y suficiente"

Reviewed on 8 Mar. 2023

Totoras Apart Federacion
See all 487 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays

All Inclusive Holidays

All Inclusive Holidays
Cheap Holidays

Cheap Holidays

Cheap Holidays

Frequently asked questions

How much does a Mesopotamia holiday package cost?
Maybe less than you might think — from only , actually! By combining hotels, flights and car rentals into your own tailor-made package, your Mesopotamia escape is just a few clicks away.
How do I get a cheap travel package to Mesopotamia?
Crafting your own Mesopotamia holiday package with Expedia is a great way to save. We offer more than 550 partner airlines and 1 000 000 hotels across the globe. With such a broad range to choose from, you’ll have no worries creating your next dream adventure.
What are the top hotels in Mesopotamia?
Costarenas Hotel & Spa and Hotel Queguay know how to make their guests feel welcome in Colon. If your itinerary also includes Parana, check out Mayim Hotel Termal & Spa and Costarenas Hotel & Spa. Both are very popular with travellers.
How far in advance should I book my Mesopotamia holiday?
It all depends on the airline, but you can usually compare international fares on Expedia nearly a year in advance. While it’s generally a good idea to book ahead of time, lucky travellers occasionally nab a cheaper ticket just weeks before departure dates.
What does an Expedia Mesopotamia travel package include?
You can choose from a combination of hotels, rental cars and flights. Once you’ve made your booking, you can add the fun stuff like experiences and activities. Want to pick your fare class? That’s also easy to do. The choice is all yours when it comes to arranging your perfect Mesopotamia trip.
What should I know before booking a Mesopotamia travel package?
Booking all the parts of your getaway together is a smart way to save. Bundle your flights, car rentals and hotels into a convenient package. But it’s not just hotels. Expedia has all types of properties, including holiday homes such as mountain cabins and serviced residences. The list is almost endless!
Can I choose my airline with a Mesopotamia Expedia holiday package?
Yes, and with over 550 airlines to select from worldwide, you’re not short on choice. Search the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Mesopotamia holiday package?
Don’t worry if you’re rethinking your Mesopotamia holiday package — you can cancel or amend your booking. And if you’ve booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We realise life can throw the occasional spanner in the works, so head to our Customer Service Portal if that occurs. When you’re ready to make changes, we’ll take care of it.

Discover the most popular places to visit in Mesopotamia

Basilica Nuestra Senora De Itati

Learn about the local history of Municipo de Itatí when you take a trip to Basilica Nuestra Senora De Itati.

Basilica Nuestra Senora De Itati