Search Mesotopos hotels

  • Plan, book, stay with confidence
    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check Mesotopos hotel prices

Tonight
26 Nov - 27 Nov
Tomorrow night
27 Nov - 28 Nov
This weekend
29 Nov - 1 Dec
Next weekend
6 Dec - 8 Dec

Filter by

Guest rating
Guest rating
Property class

Top hotels and accommodation in Mesotopos

Sappho Hotel
Exterior

Sappho Hotel

2.0 star property
8.8 out of 10, Excellent, (18)
"Great place to stay. Right in the centre of everything. Staff friendly and approachable. "
The price is AU$81
includes taxes & fees
28 Nov - 29 Nov
Sappho Hotel
Eressian Hotel & Hammam Spa
Indoor pool, outdoor pool, pool umbrellas, pool loungers

Eressian Hotel & Hammam Spa

3.0 star property
10.0 out of 10, Exceptional, (2)
"Very friendly and informative welcome. Calm from the minute you walk through the door. Only 4 rooms so felt very special. Such lovely staff."
The price is AU$191
includes taxes & fees
1 Dec - 2 Dec
Eressian Hotel & Hammam Spa
Eressian Lodgings Apartments
Terrace/patio

Eressian Lodgings Apartments

10.0 out of 10, Exceptional, (4)
"Lovely place to stay. Hosts are friendly but not in ur face."
Eressian Lodgings Apartments
'Perivoli' Stone House
Beach

'Perivoli' Stone House

'Perivoli' Stone House
Family-friendly, detached, spacious villa.
Property grounds

Family-friendly, detached, spacious villa.

Family-friendly, detached, spacious villa.
In the 'Perivoli' house B
Beach

In the 'Perivoli' house B

In the 'Perivoli' house B
Seaside Studio with Parking Steps from the Beach
Outdoor dining

Seaside Studio with Parking Steps from the Beach

Seaside Studio with Parking Steps from the Beach
Beautiful Stone House in a Peaceful Village
Beach

Beautiful Stone House in a Peaceful Village

9.0 out of 10, Wonderful, (2)
"It was lovely. We enjoyed walking to the town square to eat. Loved the food! Everyone was so nice in the town. Every day, we went to the beach. The afternoon/evening breezes were welcome as it was very hot. The outdoor patio was wonderful."
Beautiful Stone House in a Peaceful Village
'Perivoli' House A, family friendly spring and summer holidays
Beach

'Perivoli' House A, family friendly spring and summer holidays

10.0 out of 10, Exceptional, (2)
"I stayed here with my wife, 1-year old son, sister and brother in law. The home was new, with washer and electronic blinds. The owner was responsive. We had a little trouble figuring out how to get the washing machine door to open at first, but once we got the hang of it it was fine. It’s a little bit removed from the downtown area compared to other properties we considered, but still a reasonable walk to the center."
'Perivoli' House A, family friendly spring and summer holidays
Seaview Villa
Terrace/patio

Seaview Villa

Seaview Villa
Beach Studio w/ Balcony - Skala Eressos - Parking
Interior

Beach Studio w/ Balcony - Skala Eressos - Parking

Beach Studio w/ Balcony - Skala Eressos - Parking
Magnificent 1850s Heritage Villa
4 bedrooms, iron/ironing board, WiFi, bed sheets

Magnificent 1850s Heritage Villa

Magnificent 1850s Heritage Villa
Magnificent 1850s Eressian Villa Hotel in Lesvos!
Smart TV

Magnificent 1850s Eressian Villa Hotel in Lesvos!

Magnificent 1850s Eressian Villa Hotel in Lesvos!
Seaside 2BD beach apartment, Skala Eressos
2 bedrooms, iron/ironing board, WiFi, bed sheets

Seaside 2BD beach apartment, Skala Eressos

Seaside 2BD beach apartment, Skala Eressos
House 100m from Sea and Square
Outdoor dining

House 100m from Sea and Square

House 100m from Sea and Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Mesotopos
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.
Unlock Black Friday deals

Frequently asked questions

Where is the best place for a stay in Mesotopos?

Delfinia Hotel & Bungalows, located 18.1 mi (29.1 km) from the heart of Mesotopos, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Theofilos Classic Hotel and Sunrise Resort Hotel. See all available top hotels, or vacation rentals in Mesotopos.

What are some of the best holiday rentals that Mesotopos has to offer?

Villa Petri - A beautiful traditional house with a breath-taking view!: This holiday home rental outside of Mesotopos is located in the city centre, and has a fireplace, a balcony and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a fridge, a stovetop and kitchenware, so that you can cook with friends or family. You and your friends and family can relax into your holiday with amenities such as a garden. See all vacation rentals in Mesotopos.

If I need to cancel my hotel reservation in Mesotopos, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Mesotopos.

What are some hotels with pools in Mesotopos?

Pasiphae Hotel: Features a snack bar, a seasonal outdoor pool and free self-parking. Theofilos Superior Resort Hotel & Spa and Akti Hotel & Apartments are two additional hotels that offer an on-site pool. View all hotels with pools in Mesotopos.

What is staying in Mesotopos like?

Those travelling to Mesotopos will definitely enjoy the sights to see and things to do. There are 134 hotels and other accommodation options in the surrounding area. Find out more about Mesotopos.

What are the top places to visit in Mesotopos?

Places to visit in the wider area include Naturist Beach, Petrified Forest of Lesbos and Natural History Museum of the Lesvos Petrified Forest. You'll also find Skala Kallonis Beach and Iera Moni Limonos in the area. Take a look at what more there is to see and do in Expedia's Mesotopos guide.

What's the weather like in Mesotopos?

The hottest months are usually August and July, with an average temperature of 25°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Mesotopos is 715 mm.