Search Mytilene hotels

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Filter by

Guest rating
Guest rating
Property class

Top hotels and accommodation in Mytilene

Heliotrope Hotels

4.0 star property
8.6 out of 10, Excellent, (176)
"The staff was very responsive to all requests. The breakfast buffet is abundant and good. "
The price is AU$169
includes taxes & fees
15 Apr - 16 Apr
Heliotrope Hotels

Theofilos Paradise Boutique Hotel

4.0 star property
9.6 out of 10, Exceptional, (136)
"Recommended for me by friends. Very comfortable and a warm and helpful receptio, which was welcome after a transatlantic flight. Staff were fluent in English. Breakfast had a good range of choices, and with a good but not overwhelming Greekpresence"
The price is AU$207
includes taxes & fees
15 Apr - 16 Apr
Theofilos Paradise Boutique Hotel

The Loriet

4.0 star property
8.0 out of 10, Very good, (55)
"Very good excellent hotel"
The price is AU$133
includes taxes & fees
15 Apr - 16 Apr
The Loriet

Elysion Hotel

5.0 star property
9.2 out of 10, Wonderful, (41)
"."
The price is AU$271
includes taxes & fees
27 Apr - 28 Apr
Elysion Hotel

Mythical Coast Wellness Retreat

5.0 star property
8.6 out of 10, Excellent, (24)
"Great property with lovely views and friendly staff. Only issue is that the upper floors of some buildings are not handicapped accessible and you will have to carry luggage’s up the stairs. To avoid stay on one of the main buildings"
The price is AU$257
includes taxes & fees
15 Apr - 16 Apr
Mythical Coast Wellness Retreat

Lasia Hotel

3.0 star property
9.2 out of 10, Wonderful, (11)
"Enjoyed our stay. Clean and friendly staff!"
The price is AU$155
includes taxes & fees
15 Apr - 16 Apr
Lasia Hotel

Elies Residences

10.0 out of 10, Exceptional, (24)
"This hotel definitely deserves the points given. Everything in the villa was very attentive. The bed was incredibly comfortable. I loved the furniture and design of the room and the landscaping around the villas was great. Breakfast was a different experience. You are given a list of what you want for breakfast. You tick what you want off the list and write down what time you want your breakfast delivered. A member of staff will bring your breakfast to your door at that time and it will be...
The price is AU$245
includes taxes & fees
21 Apr - 22 Apr
Elies Residences

Porto Lesvos

2.0 star property
8.4 out of 10, Very good, (21)
"A very welcoming owner& also helped me reunite with a Camera I left behind. Thankyou again. The breakfast was 1st class with a variety of fruit available.I am returning to the Hotel next month."
The price is AU$107
includes taxes & fees
15 Apr - 16 Apr
Porto Lesvos

Oikies Small Elegant Houses

9.4 out of 10, Exceptional, (25)
"Our stay here was beyond enjoyable with the help of the staff (especially Katerina’s suggestions of the island!). Everyone knew English and was beyond helpful. What a great location and what a great hotel. Will be definitely coming back to stay. Thank you for everything that made this stay and vacation so much better"
The price is AU$184
includes taxes & fees
15 Apr - 16 Apr
Oikies Small Elegant Houses

Heliotrope The Studios

8.8 out of 10, Excellent, (44)
"Staff was friendly especially Maria went out of her way to assist. The place was having some renovations done new sensor lighting and furniture cabinet upgrades. All in all the stay was pleasant and comfortable."
The price is AU$129
includes taxes & fees
17 Apr - 18 Apr
Heliotrope The Studios

ISSA Lesvos

The price is AU$181
includes taxes & fees
25 Apr - 26 Apr
ISSA Lesvos

Olive Green Studios and Apartments

10.0 out of 10, Exceptional, (1)
The price is AU$232
includes taxes & fees
27 Apr - 28 Apr
Olive Green Studios and Apartments

Pebble Beach Hotel

6.0 out of 10, (5)
"The hotel was a bit dated but the AC works and the staff was very friendly and helpful. It seems very popular with Germans as all of the books in the free library were German🤓 Great hotel for the price, would definitely recommend. "
The price is AU$108
includes taxes & fees
15 Apr - 16 Apr
Pebble Beach Hotel

Maria Plomari Apartments

9.4 out of 10, Exceptional, (8)
"Location and room comfort was very nice."
The price is AU$112
includes taxes & fees
10 May - 11 May
Maria Plomari Apartments

Kaloni village apartments

8.0 out of 10, Very good, (6)
"I used it as a base for a bird watching holiday. Set in countryside, you can walk out of the bungalow and straight into it. Easy access to the main road 600 metres if you hire a car, 2.5km to the village shops and tavernas"
The price is AU$157
includes taxes & fees
15 Apr - 16 Apr
Kaloni village apartments

Aeolian Gaea Hotel

4.0 star property
9.6 out of 10, Exceptional, (7)
"Centrally located, beautiful premises- rooms and pool, great breakfast -a lovely family owned hotel. This is our 2nd summer staying here"
Aeolian Gaea Hotel

Shine Studios

9.8 out of 10, Exceptional, (8)
"We had a fantastic studio one of only four set in a beautiful area .The owners Vasso and Vangelis were wonderful people they made us very welcome and the feeling was homely.Vasso made us home cooked food pressies everyday and our room cleaned every day abd we had fresh towel s and linen daily.we had access to a small garden with sun beds back and front of the studios with a swinging hammock in the trees.We had free WiFi and free car parking area.The studios were easy to find just off a country...
The price is AU$110
includes taxes & fees
2 May - 3 May
Shine Studios
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Mytilene
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Mytilene

Mytilene is calling! Discover its museums, castle, island views and more.

Frequently asked questions

Where is the best place for a stay in Mytilene?

Theofilos Paradise Boutique Hotel is ranked highly by Expedia customers. This hotel offers a full-service spa and free breakfast. Heliotrope Hotels is another favourite option for your stay based on traveller reviews. See all available top hotels, or vacation rentals in Mytilene.

What are some of the best holiday rentals that Mytilene has to offer?

Private Modern Cozy House at the Center: This highly rated holiday home rental in Mytilene has air conditioning and Netflix to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, an oven and kitchenware. Some other homes for rent in Mytilene include Industrial Design Bungalow – 2 min to Center, Wifi and Townhouse in a quiet neighborhood-1 min from the center of the Mitilini. See all vacation rentals in Mytilene.

If I need to cancel my hotel reservation in Mytilene, will I receive a refund?

Yes, the majority of hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Mytilene.

What's the best family accommodation in Mytilene?

Heliotrope The Studios is a guesthouse with laundry facilities and free WiFi, and it's a top choice on Expedia for families. Galazio Asteri I is another good choice for your stay with the kids. Also, attractions in the area such as Vrisa Natural History Museum are fun for the whole family. Find more child-friendly accommodations in Mytilene.

What's the best hotel for a couple going to Mytilene?

Mythical Coast Wellness Retreat is a favourite hotel for couples, and features rainfall showerheads and private balconies. Other good choices for a stay with your sweetheart include Elysion Hotel and Zaira Hotel. See all romantic hotels in Mytilene.

What's the best dog-friendly hotel in Mytilene?

Theofilos Paradise Boutique Hotel is a top hotel for people travelling with their pets, and offers a full-service spa and a seasonal outdoor pool for its human guests. Other good choices for you and your pet's trip include Heliotrope Hotels and Heliotrope The Studios. See more pet-friendly hotel accommodations in Mytilene.

What's the best place to stay to stay near the beach in Mytilene?

Mythical Coast Wellness Retreat is a top beachfront hotel with 3 indoor pools and 5 restaurants, and it's located close to Kochylia . Other good choices for your stay near the beach include Heliotrope Hotels and Elysion Hotel. See more stays near the beach in Mytilene.

What's the best high-end hotel in Mytilene?

Theofilos Paradise Boutique Hotel is a luxury hotel with a full-service spa and a seasonal outdoor pool, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Mythical Coast Wellness Retreat and Elysion Hotel are two other upscale options for your stay. Find more luxury hotels in Mytilene.

What's the best boutique-style accommodation in Mytilene?

Theofilos Paradise Boutique Hotel is a favourite hotel with our travellers looking for stylish accommodation, and features 24 guestrooms, a full-service spa and a seasonal outdoor pool. See all boutique hotels in Mytilene.

What are some accommodation options with pools in Mytilene?

Theofilos Paradise Boutique Hotel: Features a children's pool, a seasonal outdoor pool and a full-service spa. Mythical Coast Wellness Retreat and Heliotrope Hotels are two additional hotels with an on-site pool. View all hotels with pools in Mytilene.

What is the best spa hotel in Mytilene?

Theofilos Paradise Boutique Hotel is a highly recommended luxury spa hotel featuring a rooftop terrace and a bar. Treat yourself to a massage at the on-site spa. Another popular spa hotel in Mytilene is Mythical Coast Wellness Retreat. See all spa hotels in Mytilene.

How is it staying in Mytilene?

Visitors to Mytilene will definitely enjoy the seaside. Tourists can also enjoy the city's museums, monuments and churches. In Mytilene, there are 70 hotels and other accommodation options to choose from. Find out more about Mytilene.

What is there to see in Mytilene?

Cultural venues include Museum of the Memorial of the Refugees of 1922, Ecclesiastical Byzantine Museum and Theriade Library and Museum of Modern Art. Landmarks like Mytilini Castle, Roman Aqueduct at Moria and St Hermogenes Charamida Lesvos might be worth a visit. The picturesque setting of Thermi Beach and Thermes Gera Hot Springs exemplify the area's natural beauty. Take a look at what more there is to see and do in Expedia's Mytilene guide.

What's the weather like in Mytilene?

The hottest months are usually August and July, with an average temperature of 25°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Mytilene is 873 mm.