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Top hotels and accommodation in Old Appleton

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1015)
"This was my first time staying at this property. I will be back. I was surprised from the moment I walked in and was greeted, my room and supper and cocktail. Wow"
Drury Inn & Suites Jackson MO

Holiday Inn Express & Suites Perryville, an IHG Hotel

2.5 star property
9.4 out of 10, Exceptional, (422)
"Needs updates. Not as clean as expected to be a Holiday Inn Express. Breakfast was tasty. "
Holiday Inn Express & Suites Perryville, an IHG Hotel

Super 8 by Wyndham Perryville

2.0 star property
8.6 out of 10, Excellent, (801)
"Great"
Super 8 by Wyndham Perryville

Quality Inn

2.5 star property
6.6 out of 10, (87)
"They only issue with the room was the sink stopper wouldn't stay put so the water ran more than it needed to "
Quality Inn

Days Inn by Wyndham Perryville

2.0 star property
6.8 out of 10, (381)
"No"
Days Inn by Wyndham Perryville

Relax in the country at Countryside Villas! - Villa A

10.0 out of 10, Exceptional, (22)
"We had a great stay! "
Relax in the country at Countryside Villas! - Villa A

The Weber Farm - Enjoy a beautiful 100 acre farm!

10.0 out of 10, Exceptional, (29)
"The Weber Farm and Family are amazing. We were in area for a family reunion. We really wanted to stay and relax at the farmhouse with Aussie( the Weber family dog). Definitely want to return. It was very clean and inviting. Communication was great. "
The Weber Farm - Enjoy a beautiful 100 acre farm!

Urban Lofts

3.0 star property
9.2 out of 10, Wonderful, (17)
"Great place to stay! "
Urban Lofts

Downtown Loft w/ Amazing Bath Tub & Shower

10.0 out of 10, Exceptional, (2)
"The location and room is absolutely awesome. It will be my default place to stay every time I come to Perryville. The disclaimer on the website says it may be noisy because of the restaurant and bar below. But we were there over a weekend and heard nothing from below. Huge upgrade compared to local hotels and the best restaurant in town with a huge beer selection is right below you. You will not be disappointed with this choice!"
Downtown Loft w/ Amazing Bath Tub & Shower

Villa B offers peace and quiet with beautiful views of the countryside.

10.0 out of 10, Exceptional, (7)
"Our stay was amazing. Everything was so clean organized, and anything you would possibly need was in the room. We will definitely be staying there again when in the area!!"
Villa B offers peace and quiet with beautiful views of the countryside.

Downtown Urban Loft above Restaurants

Downtown Urban Loft above Restaurants

Urban Loft #1 RED · Urban Loft Downtown above BrewCo & Restaurant

Urban Loft #1 RED · Urban Loft Downtown above BrewCo & Restaurant

Downtown Urban Loft above Restaurant

"One of the most incredible places i've stayed on VRBO. "
Downtown Urban Loft above Restaurant

Gorgeous, downtown house!

Gorgeous, downtown house!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

What's the best place to stay in Old Appleton?

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, located 17.7 mi (28.5 km) from the heart of Old Appleton, is a top choice for your stay, based on our traveller data. Two other choices for your visit to the area are Holiday Inn Express & Suites Perryville, an IHG Hotel and Quality Inn. See all available top hotels, or vacation rentals in Old Appleton.

What are some of the best holiday rentals that Old Appleton has to offer?

Notting Hill Cottage: This holiday home rental outside of Old Appleton offers a patio, a private garden and a BBQ to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. You and your friends and family can relax into your holiday with amenities such as 1 hot tub. See all vacation rentals in Old Appleton.

If I need to cancel my hotel reservation in Old Appleton, will I receive a refund?

Yes, you'll find most hotel room reservations are refundable if you cancel before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Old Appleton.

What are some accommodation options with pools in Old Appleton?

Auburn Place Hotel And Suites: Offers free buffet breakfast, an indoor pool and free Internet. Drury Plaza Hotel Cape Girardeau Conference Center and Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel are two additional hotels that offer an on-site pool. View all hotels with pools in Old Appleton.

What is staying in Old Appleton like?

Visitors to Old Appleton will definitely find plenty to explore and enjoy. There are 45 hotels and other accommodation options in the surrounding area. Find out more about Old Appleton.

What should I see while I'm in Old Appleton?

Places to visit in the wider area include Perryville Country Club, National Shrine of Our Lady of the Miraculous Medal and Trail of Tears State Park. You'll also find Steele Crest Winery and Missouri's National Veterans Memorial in the area. Take a look at what more there is to see and do in Expedia's Old Appleton guide.

What's the weather like in Old Appleton?

The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 4°C. Average annual precipitation for Old Appleton is 1435 mm.