Perryville Holiday Rentals

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Holiday Rentals in Perryville

Urban Lofts

3.0 star property
9.2 out of 10, Wonderful, (17)
"Great place to stay! "
Urban Lofts

'The Brewer Guesthouse' Tiny Home w/ Patio & Yard!

10.0 out of 10, Exceptional, (8)
"As always a great place to relax and enjoy the country sitting. Always very clean, all the pots & pans you need, and towels. "
'The Brewer Guesthouse' Tiny Home w/ Patio & Yard!

Gorgeous, downtown house!

The price is AU$1,177
includes taxes & fees
24 Nov - 25 Nov
Gorgeous, downtown house!

'the Brewer Guesthouse' Tiny Home w/ Patio & Yard!

3.0 star property
10.0 out of 10, Exceptional, (2)
"It was a very neat cottage to stay in. We would definitely stay again. So much nicer than staying a hotel. "
'the Brewer Guesthouse' Tiny Home w/ Patio & Yard!

Downtown Loft w/ Amazing Bath Tub & Shower

10.0 out of 10, Exceptional, (2)
"The location and room is absolutely awesome. It will be my default place to stay every time I come to Perryville. The disclaimer on the website says it may be noisy because of the restaurant and bar below. But we were there over a weekend and heard nothing from below. Huge upgrade compared to local hotels and the best restaurant in town with a huge beer selection is right below you. You will not be disappointed with this choice!"
The price is AU$373
includes taxes & fees
1 Dec - 2 Dec
Downtown Loft w/ Amazing Bath Tub & Shower

Urban Loft #1 RED · Urban Loft Downtown above BrewCo & Restaurant

The price is AU$377
includes taxes & fees
10 Dec - 11 Dec
Urban Loft #1 RED · Urban Loft Downtown above BrewCo & Restaurant

Entire Private Home in Perryville, MO

10.0 out of 10, Exceptional, (2)
"Very clean house with everything you would need for a short or long stay. There is a seating area out back where you can enjoy watching the wild life in the woods. The owner is supper nice."
Entire Private Home in Perryville, MO

Urban Lofts

4.0 star property
Urban Lofts

Rated#1 Big Sky Cabin! 🍷 On the Wine Trail Hot Tub 🔥 FirePit Pool 🎱 Table

9.8 out of 10, Exceptional, (155)
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Rated#1 Big Sky Cabin! 🍷 On the Wine Trail Hot Tub 🔥 FirePit Pool 🎱 Table

Downtown historic main street

9.6 out of 10, Exceptional, (176)
"The area was very eclectic and fun. Very unique area. Needs a little work yet but was informed of that from the get go. "
The price is AU$222
includes taxes & fees
26 Nov - 27 Nov
Downtown historic main street

Cozy Three bedroom home in Central Farmington

9.6 out of 10, Exceptional, (15)
"We came into town for opening weekend of deer season and need a convenient place to stay. We found this listing and reserved the home for the weekend. The home was clean and very welcoming and met all of our expectations. The owner was very accommodating and eager to help however needed. We enjoyed our stay!"
The price is AU$402
includes taxes & fees
29 Nov - 30 Nov
Cozy Three bedroom home in Central Farmington

Micro house cabin located near Silver Mines Recreation Area.

10.0 out of 10, Exceptional, (57)
"Very relaxing and unique, very clean with almost everything ! Lots of trails within 20 minutes. Great stay !"
Micro house cabin located near Silver Mines Recreation Area.

Romantic renovated country cabin with views.

9.6 out of 10, Exceptional, (5)
"This is the perfect place for a girl’s trip or family getaway! The property is gorgeous with lots of room for outdoor activities. If the weather doesn’t permit, the house is spacious and filled with activities such as board games, instruments if your family or friends are musically inclined, books, and television. The check in and checkout process was smooth, and the host was very responsive when we had questions. We left with all 11 in our group wanting to return each year to this perfect...
Romantic renovated country cabin with views.

Your home away from home in downtown, historic Farmington!

10.0 out of 10, Exceptional, (19)
"The carriage house was just as described. Very nice and very clean. Lena was quick to respond and extremely helpful. Would definitely stay here again. "
The price is AU$327
includes taxes & fees
27 Nov - 28 Nov
Your home away from home in downtown, historic Farmington!

Secluded Private Cabin with Pool, hot tub, fireplace & so much more

10.0 out of 10, Exceptional, (121)
"We came in town for a short weekend, as a group of 14. Plenty of room for all of us and lots of activities for all ages. The kitchen is very well stocked with everything you could need. We are already talking about returning to this property, or the neighboring one. Thanks, Emma for your hospitality! "
Secluded Private Cabin with Pool, hot tub, fireplace & so much more

Newly remodeled house close to downtown and minutes away from golf courses

2.0 star property
9.8 out of 10, Exceptional, (8)
"This property worked well for our needs. Very convenient location to gas, food and golf course. "
The price is AU$276
includes taxes & fees
1 Dec - 2 Dec
Newly remodeled house close to downtown and minutes away from golf courses

Murphysboro Retreat w/ Deck Near Kinkaid Lake!

10.0 out of 10, Exceptional, (14)
"Great spot close to some family local. "
Murphysboro Retreat w/ Deck Near Kinkaid Lake!

Hilltop Retreat 2: Spacious, pond-front home for 12 near wine trail!

9.8 out of 10, Exceptional, (21)
"We absolutely loved the property. It sits right on a pond that my two sons fished on everyday. They caught bass crappie and blue gill. The house was very spacious and clean. I was shocked to not see ANY bugs since it is in a wooded area. Major plus!!! The kitchen had everything we needed. The host very responsive when we needed her. The lakes were about 15 min away, shopping was about 25 min away. There are plenty of wineries and hikes. I do recommend going to giant city and eating at the lodge...
Hilltop Retreat 2: Spacious, pond-front home for 12 near wine trail!

Ste. Genevieve Co. House w/ HOT TUB!

9.6 out of 10, Exceptional, (5)
"The property could use an update but it was good for what we needed"
Ste. Genevieve Co. House w/ HOT TUB!

Cozy Haven Little Hidden Gem Sleeps 4

10.0 out of 10, Exceptional, (36)
"I will absolutely be returning! "
Cozy Haven Little Hidden Gem Sleeps 4
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other types of properties in Perryville you may be interested in

Holiday Inn Express & Suites Perryville, an IHG Hotel

2.5 star property
9.4 out of 10, Exceptional, (422)
"Very clean property the rooms were very clean and like new. The breakfast was your typical hotel breakfast. I would recommend staying here if you come to Perryville"
The price is AU$174
includes taxes & fees
28 Nov - 29 Nov
Holiday Inn Express & Suites Perryville, an IHG Hotel

Super 8 by Wyndham Perryville

2.0 star property
8.6 out of 10, Excellent, (801)
"Great"
The price is AU$114
includes taxes & fees
8 Dec - 9 Dec
Super 8 by Wyndham Perryville

Days Inn by Wyndham Perryville

2.0 star property
6.8 out of 10, (381)
"No"
The price is AU$123
includes taxes & fees
24 Nov - 25 Nov
Days Inn by Wyndham Perryville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

Can I find a holiday rental in Perryville?

Yes, there are holiday rentals close to the most popular sights in Perryville, or you can select a more secluded option if you're looking for a relaxing stay. Perryville is known for its wineries and golf courses. Make sure you have time to check out the coffee shops and festivals during your trip.

What are some of the best holiday rentals that Perryville has to offer?

'The Brewer Guesthouse' Tiny Home w/ Patio & Yard!: This highly rated holiday home rental in Perryville offers a patio, a private garden and air conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. You and your friends and family can relax into your holiday with amenities such as a selection of books.

How many holiday rentals will I find in Perryville?

With 5 Expedia holiday rentals, you're guaranteed to find just the right place for your Perryville stay.

What’s there to see and do in Perryville?

Mark Twain National Forest and Mississippi River are a couple of lovely local spots to get outside and enjoy nature. While here, National Shrine of Our Lady of the Miraculous Medal and Perryville Country Club are other places worth a visit.

What’s a holiday rental in Perryville like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Perryville. Holiday rentals provide amenities such as WiFi and washers and dryers so you'll feel just like you're at home. If you're concerned about cleanliness, a holiday rental can provide a sense of security away from public hotel lifts and busy concierge desks while still allowing you to travel. You'll also get more space in a holiday rental than in a traditional hotel, which is another reason why a holiday rental is a great option for a family trip.