Unique features of Jerusalem City Centre include the historical sites and museums. Make a stop by Ben Yehuda Street or Jerusalem Great Synagogue while you're exploring the area.
Unique features of Old City include the historical sites and shopping. Make a stop by Via Dolorosa or Convent of the Sisters of Zion while you're exploring the area.
If you're spending some time in Mamilla, Ben Yehuda Street and Mamilla Mall are top sights worth seeing.
While visiting Nachlaot, you might make a stop by sights like Machane Yehuda Market and Ben Yehuda Street.
While Talbieh may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Jerusalem Great Synagogue and The First Station.