San Antonio Holidays from AU$741

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Your San Antonio Holiday

With a reputation for its rich history and cultural experiences, San Antonio is an ideal getaway destination. Lock in one of our San Antonio holiday packages and immerse yourself in all that this fascinating city has to offer. In the mood to explore the sights but unsure where to start? Every trip to San Antonio should include Metromall Panama. Stop daydreaming and start travelling. Explore the wide range of options on Expedia today and finally put your San Antonio holiday plans into action!

Top Holiday Package Deals in San Antonio

Price found within the past 48 hours. Click for updated prices.
Hotel Casa Panamá

Hotel Casa Panamá

4 out of 5
Casco Viejo
per person
28 Feb - 2 Mar
found 12 hours ago
Return flight included
Medellín (MDE) to Panama City (PTY)
7.4/10 Good! (494 reviews)
Only stayed 1 night. Average stay Good location for price. Room, staff was fine. On 1st floor so if Rooftop was loud didnt hear. Hotel arranged taxi and storaged our luggage while we were out.

Reviewed on 23 Jan. 2025

Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
per person
28 Feb - 2 Mar
found 12 hours ago
Return flight included
Medellín (MDE) to Panama City (PTY)
7.4/10 Good! (1,000 reviews)
It was a little far away from downtown Panama city which to me was great. Everything about this place was beautiful.

Reviewed on 24 Jan. 2025

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
per person
28 Feb - 2 Mar
found 12 hours ago
Return flight included
Medellín (MDE) to Panama City (PTY)
9/10 Wonderful! (792 reviews)
Amazing location, Stafford, friendly on all accounts amazing service as well. Highly recommend hope to come back soon.

Reviewed on 23 Jan. 2025

Hotel La Compania, in the Unbound Collection by Hyatt

Hotel La Compania, in the Unbound Collection by Hyatt

4.5 out of 5
Casco Viejo
per person
28 Feb - 2 Mar
found 12 hours ago
Return flight included
Medellín (MDE) to Panama City (PTY)
9.8/10 Exceptional! (184 reviews)
This is a gorgeous hotel with experienced and professional staff. It makes any trip to Panama City perfect!

Reviewed on 20 Jan. 2025

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
San Francisco
per person
28 Feb - 2 Mar
found 12 hours ago
Return flight included
Medellín (MDE) to Panama City (PTY)
8.8/10 Excellent! (1,000 reviews)
The architectural design was absolutely beautiful! Staff was very friendly. Rooms were clean and well kept. Housekeeping was always on-point with cleaning every day. Breakfast was amazing, loved the daily options. Food at the on property restaurant was really good and they had a variety of options

Reviewed on 16 Jan. 2025

Our guide on where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most. Learn more about San Antonio
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Rufina Alfaro

1 out of top 10 points of interest in this area

Rufina Alfaro might not have many top sights, but Metromall Panama and Los Pueblos Commercial Center are two attractions nearby that you can check out.

Find hotels in Rufina Alfaro

Our pick of the best San Antonio Hotel Deals

Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is AU$219 per night from 28 Jan to 29 Jan
AU$219
includes taxes & fees
28 Jan - 29 Jan
9/10 Wonderful! (3,537 reviews)
"Where to start? We have travelled a lot and yet I believe this is the best hotel at which we have ever stayed. The cleanliness, the linens (ironed and smelled a tiny bit like lavendar), the super employees, the BREAKFAST, the location—perfect!"

Reviewed on 23 Jan. 2025

Hotel Riu Plaza Panama
Waldorf Astoria Panama
Waldorf Astoria Panama
5 out of 5
47th St. & Uruguay Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is AU$321 per night from 23 Feb to 24 Feb
AU$321
includes taxes & fees
23 Feb - 24 Feb
8.8/10 Excellent! (1,000 reviews)
"Loved it and great service . Will return"

Reviewed on 17 Jan. 2025

Waldorf Astoria Panama
Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is AU$157 per night from 19 Feb to 20 Feb
AU$157
includes taxes & fees
19 Feb - 20 Feb
9.2/10 Wonderful! (1,797 reviews)
"Excellent Location in the city! Beautiful view of the city and the waterfront! Convenient location to family friendly play areas and wanks along the water. Breakfast buffet was impressive!"

Reviewed on 24 Jan. 2025

Plaza Paitilla Inn Hotel
See all 1,308 properties in San Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays

All Inclusive Holidays

All Inclusive Holidays
Cheap Holidays

Cheap Holidays

Cheap Holidays
beach holidays

Beach Holidays

Beach Holidays

Frequently asked questions

How much does a San Antonio holiday package cost?
Choose from any combination of car rentals, flights and hotels, and you can be holidaying in San Antonio from just AU$741. And the more you bundle, the more cash you save. The holiday of your dreams has never been more affordable.
How do I get a cheap travel package to San Antonio?
Our San Antonio holiday packages promise plenty of savings for the savvy traveller. For the best deal, simply combine your flights, hotels and extras (including tours) into one neat package. But great bargains are only the start of your next unforgettable adventure. Book with Expedia and and you’ll have over 550 airlines and 1 000 000 hotel options across the globe to pick from. Whatever your budget or style, there’s a holiday package that’s perfect for you.
Where should I stay in San Antonio?
If you’re interested in visiting Metromall Panama, give commuting a miss and book a hotel nearby. It’s one of the best attractions in this neighbourhood.
What are the top hotels in San Antonio?
Dumas Villas is one of San Antonio’s most popular properties. Lock in a room here and you’ll slumber peacefully knowing you’re in capable hands.
How far in advance should I book my San Antonio holiday?
Search Expedia to compare international airfares ASAP. You can usually purchase a seat up to 12 months in advance. If you can’t see your preferred air carrier, or you’ve left things to the last minute, don’t stress. Cheap fares to San Antonio sometimes occur within weeks of the date of departure.
What does an Expedia San Antonio travel package include?
From airfares and hotels to rental cars, Expedia can help you put together a San Antonio package that’s right for you. Holidaying for a few weeks? Check out a rental car, flight and hotel bundle. If your break is short, a hotel and flight deal may be more your style. Experiences can also be added once you’ve made your booking. Our holiday packages make it a cinch to plan and save.
What should I know before booking a San Antonio travel package?
So many places to explore, so many things to do. With a package, you can check more of them off your list. Bundle your hotels, flights and rental cars and get set to save.
Can I choose my airline with a San Antonio Expedia holiday package?
Yes — that’s the beauty of an Expedia holiday package. You’re in control. We have more than 550 airline partners all over the world, so you have lots of choice when putting together your San Antonio getaway.
If I'm not able to travel, can I cancel my San Antonio holiday package?
We totally get it — unexpected stuff happens. If you’ve booked a San Antonio holiday package and need to cancel or amend it, we can help. We recommend browsing our Customer Service Portal first for information. But generally, if you’ve booked your package within 24 hours, you may be able to cancel or amend your itinerary for free. If it’s been longer than 24 hours, your hotel, airline or car rental company may impose a fee.

Activities

Panama city and canal tour's unforgettable.

Panama city and canal tour's unforgettable.

AU$97
per adult
100% of travellers recommend
Panama city and canal tour's unforgettable.
Day Tour

Day Tour in San Blas Islands All Included Visiting 4 Islands

AU$241
per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
Panama City: Poin Glass Observation Deck Ticket with VR Tour

Panama City: Poin Glass Observation Deck Ticket with VR Tour

AU$52
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
See all activities in San Miguelito
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.