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Top hotels and accommodation in San Francisco

Hotel Mykonos Panama

3.5 star property
8.8 out of 10, Excellent, (464)
"great"
The price is AU$220
includes taxes & fees
1 Jan - 2 Jan 2025
Hotel Mykonos Panama

HOTEL PLAZA COROTÚ

3.0 star property
The price is AU$77
includes taxes & fees
24 Dec - 25 Dec
HOTEL PLAZA COROTÚ

Hotel Galería

3.0 star property
8.2 out of 10, Very good, (173)
"Very nice beds "
The price is AU$120
includes taxes & fees
1 Jan - 2 Jan 2025
Hotel Galería

Hotel Gran David

3.5 star property
8.4 out of 10, Very good, (281)
"I stayed here several times. I have always enjoyed staying here. However, I’ve noticed the food quality slipping this trip. I alerted the staff to my dissatisfaction regarding food that I ordered"
The price is AU$171
includes taxes & fees
24 Dec - 25 Dec
Hotel Gran David

HOTEL VISTA LAGO

3.0 star property
8.8 out of 10, Excellent, (16)
"Nice property. I liked it. "
The price is AU$150
includes taxes & fees
24 Dec - 25 Dec
HOTEL VISTA LAGO

Hotel Anachoreo

3.0 star property
9.4 out of 10, Exceptional, (26)
"The view from the hotel is amazing. There is a beautiful garden you can walk through and see various floral and fauna. A very tasty and filling breakfast is served in the morning. You can easily walk to several restaurants, the bus station, and a market. Graciela brought tea most evenings to my room. The only negative for me is that the room did get quite hot some days. I will return though."
The price is AU$157
includes taxes & fees
25 Dec - 26 Dec
Hotel Anachoreo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place for a stay in San Francisco?

Hotel Mykonos Panama, located 10.4 mi (16.8 km) from the heart of San Francisco, is a top choice for your stay, based on our traveller data. Other good options for your stay in the area are Hotel Gran David and Hotel Galería. See all available top hotels, or vacation rentals in San Francisco.

What are some of the best holiday rentals that San Francisco has to offer?

Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone: This holiday home rental outside of San Francisco has air conditioning and a Smart TV to help you feel perfectly comfortable in your new surroundings. Kitchen amenities such as a stovetop and a microwave can make your holiday run smoothly. See all vacation rentals in San Francisco.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! You'll find that most room reservations are refundable if you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in San Francisco.

What is staying in San Francisco like?

Visitors to San Francisco will definitely find plenty to explore and enjoy. There are 19 hotels and other accommodation options in the surrounding area. Find out more about San Francisco.

What should I see while I'm in San Francisco?

Places to visit in the wider area include Parque Acuatico Italia Guadalupe Panama, Laguna de La Yeguada and Los Pozos Termales. You'll also find Parque Nacional Cerro Hoya and Cerámica La Peña in the area. Take a look at what more there is to see and do in Expedia's San Francisco guide.

What's the seasonal weather like in San Francisco?

The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and December, with an average of 25°C. The rainiest months in San Francisco are October, August, June and November, with each month seeing an average of 447 mm of rainfall.