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Top hotels and accommodation in Santa Ana

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Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! Most hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Ana.

What is there to see in Santa Ana?

Places to visit in the wider area include Calilegua National Park, Hornocal Mountain Range and Hornocal Mountain Range Viewpoint. Take a look at what more there is to see and do in Expedia's Santa Ana guide.

What's the weather like in Santa Ana?

The hottest months are usually December and January, with an average temperature of 22°C, while the coldest months are July and June, with an average of 14°C. The rainiest months in Santa Ana are February, January, December and March, with each month seeing an average of 253 mm of rainfall.