Search Santa Ana hotels

  • Plan, book, stay with confidence
  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check Santa Ana hotel prices

Tomorrow night
This weekend
Next weekend

Filter by

Guest rating
Guest rating
Property class

Top hotels and accommodation in Santa Ana

Save an average of 15% on thousands of hotels when you're signed in
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

Where is the best place to stay in Santa Ana?

Portal de la Marquesa, located 18.3 mi (29.4 km) from the heart of Santa Ana, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Bioma Boutique Hotel and La Casa Amarilla. See all available top hotels, or vacation rentals in Santa Ana.

What are some of the best holiday rentals that Santa Ana has to offer?

Encantador Apartamento Diseñado Para ti!: This holiday home rental outside of Santa Ana has air conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Santa Ana.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a reservation that's non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Ana.

What are some accommodation options with pools in Santa Ana?

Portal de la Marquesa: Features free cooked-to-order breakfast, 2 outdoor swimming pools and free WiFi. San Rafael and Bioma Boutique Hotel are two additional hotels that feature an on-site pool. View all hotels with pools in Santa Ana.

What's it like to stay in Santa Ana?

Visitors will definitely enjoy all that Santa Ana has to offer. There are 35 hotels and other accommodation options in the surrounding area. Find out more about Santa Ana.

What should I do while I'm visiting Santa Ana?

A favourite place to visit is Magdalena River. You'll also find Church of St. Francis and Church of the Immaculate Conception in the area. Take a look at what more there is to see and do in Expedia's Santa Ana guide.

What's the seasonal weather like in Santa Ana?

The hottest months are usually February and March, with an average temperature of 29°C, while the coldest months are November and December, with an average of 27°C. The rainiest months in Santa Ana are May, August, October and September, with each month seeing an average of 346 mm of rainfall.