Santa Ana Hotels, Antigua Guatemala

  • Plan, book, stay with confidence
    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Filter by

Guest rating
Guest rating
Property class

1048 Cheap Hotels in Santa Ana - Specials, Reviews, & Last Minute Deals

Hotel Museo Spa Casa Santo Domingo
View from property

Hotel Museo Spa Casa Santo Domingo

4.5 star property
9.2 out of 10, Wonderful, (1012)
"Best hotel in Guatemala!"
The price is AU$507
includes taxes & fees
1 Dec - 2 Dec
Hotel Museo Spa Casa Santo Domingo
Hotel Soleil La Antigua
3 outdoor pools, pool umbrellas

Hotel Soleil La Antigua

4.0 star property
8.6 out of 10, Excellent, (1053)
"Overall service was excellent. Breakfast was amazing. But notice that Dollar exchange was lower than what it was going for. It was 1.00Q less. So for example if $1.00 to Q6.30 opposed to what it should be $7.30Q. "
The price is AU$216
includes taxes & fees
2 Dec - 3 Dec
Hotel Soleil La Antigua
Hotel Camino Real Antigua
Bar (on property)

Hotel Camino Real Antigua

4.0 star property
9.6 out of 10, Exceptional, (1019)
"Beatiful hotel"
The price is AU$390
includes taxes & fees
2 Dec - 3 Dec
Hotel Camino Real Antigua
Hotel Posada de Don Rodrigo Antigua
Exterior

Hotel Posada de Don Rodrigo Antigua

3.5 star property
9.4 out of 10, Exceptional, (479)
"The boutique nature of the hotel was very nice."
The price is AU$328
includes taxes & fees
6 Dec - 7 Dec
Hotel Posada de Don Rodrigo Antigua
Porta Hotel Antigua
Property amenity

Porta Hotel Antigua

4.5 star property
9.2 out of 10, Wonderful, (982)
"This is a beautiful hotel with excellent staff and amenities. I highly recommend it!"
The price is AU$320
includes taxes & fees
1 Dec - 2 Dec
Porta Hotel Antigua
Hotel Casa Antigua
Property grounds

Hotel Casa Antigua

3.0 star property
8.0 out of 10, Very good, (389)
"Great location! Minutes from everyplace"
The price is AU$120
includes taxes & fees
24 Dec - 25 Dec
Hotel Casa Antigua
Good Hotel Antigua
Deluxe Room Garden View | Terrace/patio

Good Hotel Antigua

4.0 star property
9.2 out of 10, Wonderful, (434)
"Great stay"
The price is AU$176
includes taxes & fees
3 Dec - 4 Dec
Good Hotel Antigua
Hotel Casa del Parque
Aerial view

Hotel Casa del Parque

3.5 star property
8.2 out of 10, Very good, (362)
"El barrio club no Deja dormir "
The price is AU$189
includes taxes & fees
24 Dec - 25 Dec
Hotel Casa del Parque
Hotel Convento Santa Catalina
Front of property

Hotel Convento Santa Catalina

3.5 star property
7.8 out of 10, Good, (318)
"Place was nice but the bed mattress was old and somewhat uncomfortable. The help and waiter’s were very friendly and the restaurant was delicious. "
The price is AU$160
includes taxes & fees
24 Dec - 25 Dec
Hotel Convento Santa Catalina
Naif Boutique Hotel
Handrails in hallways

Naif Boutique Hotel

3.0 star property
9.0 out of 10, Wonderful, (242)
"We lived our stay and would recommend Naif Boutique Hotel to friends. The staff was friendly, helpful and accommodating!"
The price is AU$223
includes taxes & fees
4 Dec - 5 Dec
Naif Boutique Hotel
Hotel La Catedral
Terrace/patio

Hotel La Catedral

4.0 star property
9.4 out of 10, Exceptional, (500)
"Great location!!! The hotel is located is just off the Centrale Plaza and easy to walk to everywhere within Antigua. The rooms were comfortable and clean at a good rate. The staff were very friendly and helpful. The included breakfast was delicious and set a great start to each day."
The price is AU$337
includes taxes & fees
7 Dec - 8 Dec
Hotel La Catedral
El Convento Boutique Hotel
Premium Suite, 1 King Bed

El Convento Boutique Hotel

4.0 star property
9.4 out of 10, Exceptional, (671)
"Beautiful!"
El Convento Boutique Hotel
Santo Cielo by Casa Santo Domingo
In-room safe, free WiFi, bed sheets

Santo Cielo by Casa Santo Domingo

3.5 star property
9.4 out of 10, Exceptional, (423)
"Great place to relax"
The price is AU$357
includes taxes & fees
26 Nov - 27 Nov
Santo Cielo by Casa Santo Domingo
Hotel Boutique Los Pasos & Spa
Terrace/patio

Hotel Boutique Los Pasos & Spa

4.5 star property
9.4 out of 10, Exceptional, (917)
"Muy comodo y servicio atento"
The price is AU$278
includes taxes & fees
4 Dec - 5 Dec
Hotel Boutique Los Pasos & Spa
Las Camelias Inn
Interior

Las Camelias Inn

3.0 star property
8.6 out of 10, Excellent, (442)
"A beautiful hotel in Antigua, The staff is really friendly, helpful. I would stay here again."
The price is AU$126
includes taxes & fees
1 Dec - 2 Dec
Las Camelias Inn
El Carmen Hotel
Terrace/patio

El Carmen Hotel

3.0 star property
8.8 out of 10, Excellent, (490)
"It was one of our better stays. The rate included breakfast located on the rooftop which was very pleasant and the food was good. very good location near the main central park. The room was a little awkward. It had two full beds that were raised on platforms that were so high that they included a step stool to help with getting onto the bed. Shower and hot water was very good. Because of configuration, the room was very tight."
The price is AU$207
includes taxes & fees
2 Dec - 3 Dec
El Carmen Hotel
Meson Panza Verde
Suite, Non Smoking, Balcony | Terrace/patio

Meson Panza Verde

3.5 star property
9.2 out of 10, Wonderful, (366)
"I stayed here last minute because my flight got canceled. Its a beautiful hotel. The rooms and grounds are beautiful. Very high end. I ate at the restaurant which was great. check in was easy. "
The price is AU$195
includes taxes & fees
19 Dec - 20 Dec
Meson Panza Verde
Nico Hotel
Traditional Single Room, 1 Queen Bed

Nico Hotel

3.0 star property
9.2 out of 10, Wonderful, (164)
"Great place staying herebinnyhe future!!!"
The price is AU$111
includes taxes & fees
9 Dec - 10 Dec
Nico Hotel
Las Cruces Boutique Hotel
Exterior

Las Cruces Boutique Hotel

4.0 star property
9.8 out of 10, Exceptional, (136)
"Stunning accommodations, friendly staff, great location, helped with coordinating transportation. "
The price is AU$401
includes taxes & fees
11 Dec - 12 Dec
Las Cruces Boutique Hotel
Hotel Las Marías
Property entrance

Hotel Las Marías

3.0 star property
9.2 out of 10, Wonderful, (354)
"Las habitaciones son comodas, limpias, algo pequeñas. El personal es atento y amable, el desayuno esta bien. El hotel queda alejado del centro, no lo recomendaria para mujeres que viajan solas "
The price is AU$165
includes taxes & fees
17 Dec - 18 Dec
Hotel Las Marías
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Santa Ana
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.
Unlock Black Friday deals

Frequently asked questions

What's it like in Santa Ana?

Travellers to the Santa Ana neighbourhood in Antigua Guatemala will be sure to enjoy their stay.

What's a favourite place to stay in Santa Ana?

Based on our traveller data, Casa Buho B&B is one of the top choices for your stay in Santa Ana. This hotel offers a restaurant and free parking.

How many hotels will I be able to find in Santa Ana?

If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 10 hotels and other accommodation options in Santa Ana.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view top deals in Santa Ana.

What are the top things to see and do in Santa Ana?

Iglesia de la Escuela de Cristo, Church of San Francisco and House of the Giants are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, make sure that you visit other sights such as Santa Clara Convent or Jade Maya Factory and Museum.