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Top hotels and accommodation in Santa Clara

Gran Evenia Panama

4.5 star property
9.2 out of 10, Wonderful, (167)
"This was a great Boutique Hotel in the Downtown area of Panama city. The suite was large, renovated nicely, with a comfortable bed and high pressure shower with steaming hot water."
Gran Evenia Panama

American Trade Hotel

4.5 star property
9.4 out of 10, Exceptional, (536)
"Such a gorgeous heritage property in a quaint historic area. Staff were amazing too. Will definitely return for a longer stay. "
The price is AU$370
includes taxes & fees
4 Aug - 5 Aug
American Trade Hotel

Las Americas Golden Tower Panama

4.0 star property
8.8 out of 10, Excellent, (1003)
"Great stay"
The price is AU$231
includes taxes & fees
2 Aug - 3 Aug
Las Americas Golden Tower Panama

Hotel Milan

3.0 star property
9.0 out of 10, Wonderful, (367)
"Nice hotel to stay. Very convenient with shopping, restaurants within walking distance."
The price is AU$67
includes taxes & fees
16 July - 17 July
Hotel Milan

Hotel San Felipe

4.0 star property
9.4 out of 10, Exceptional, (171)
"Great location, walkable to tourists attractions and restaurants, excellent staff "
The price is AU$223
includes taxes & fees
13 July - 14 July
Hotel San Felipe

Plaza Paitilla Inn Hotel

3.5 star property
9.4 out of 10, Exceptional, (2071)
"Great stay!"
The price is AU$252
includes taxes & fees
31 July - 1 Aug
Plaza Paitilla Inn Hotel

Principe Hotel and Suites

3.0 star property
9.0 out of 10, Wonderful, (1396)
"Good place to stay. "
The price is AU$98
includes taxes & fees
13 July - 14 July
Principe Hotel and Suites

Radisson Hotel Panama Canal

4.5 star property
8.4 out of 10, Very good, (1002)
"It's a very peaceful and easy place to get to from the west"
The price is AU$135
includes taxes & fees
19 July - 20 July
Radisson Hotel Panama Canal

Best Western El Dorado Panama Hotel

3.0 star property
9.0 out of 10, Wonderful, (574)
"Great stay"
The price is AU$132
includes taxes & fees
2 Aug - 3 Aug
Best Western El Dorado Panama Hotel

Hotel Plaza Herrera

3.0 star property
10.0 out of 10, Exceptional, (3)
"I’ve stayed in boutique hotels across Europe and Latin America — and this one tops the list. Hotel Herrera blends elegance, story, and soul. It feels like the kind of place you want to stumble upon — and then never leave. Plaza Herrera out your door. Rooftops, ruins, and real culture at your feet. There’s no better base for exploring Panama City’s heart than this hotel. You’re in it — part of the rhythm, the flavor, and the magic. I will be back and bringing friends!!"
The price is AU$328
includes taxes & fees
1 Aug - 2 Aug
Hotel Plaza Herrera

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
9.6 out of 10, Exceptional, (589)
"The staff was very friendly. "
The price is AU$341
includes taxes & fees
1 Aug - 2 Aug
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Toscana Inn

3.5 star property
9.0 out of 10, Wonderful, (713)
"Clean rooms, friendly and helpful staff Close to City, outlet stores and Metro"
Toscana Inn

Marriott Executive Apartments Panama City, Finisterre

4.0 star property
8.8 out of 10, Excellent, (613)
"The staff was super friendly and accommodating!"
The price is AU$169
includes taxes & fees
26 July - 27 July
Marriott Executive Apartments Panama City, Finisterre

TRYP by Wyndham Panamá Centro

3.5 star property
9.0 out of 10, Wonderful, (1007)
"Hotel very clean and the staff was excellent "
The price is AU$144
includes taxes & fees
27 July - 28 July
TRYP by Wyndham Panamá Centro

Renaissance Panama City Hotel

5.0 star property
8.8 out of 10, Excellent, (28)
"Everything was nice clean friendly staff"
The price is AU$172
includes taxes & fees
18 July - 19 July
Renaissance Panama City Hotel

Nomada Container Hotel Panama City

3.0 star property
8.8 out of 10, Excellent, (140)
"I loved this place- great location, friendly staff, clean and comfy for a nice price. I've already booked my next stay!"
The price is AU$107
includes taxes & fees
13 July - 14 July
Nomada Container Hotel Panama City

Waymore Hotel Spa & Casino

4.0 star property
9.2 out of 10, Wonderful, (333)
"This place was awesome"
The price is AU$134
includes taxes & fees
18 July - 19 July
Waymore Hotel Spa & Casino

Hotel Ojos del Rio

3.5 star property
8.2 out of 10, Very good, (807)
"Clean hotel with fantastic staff & management. We loved our stay and really enjoyed the time.. Excellent experience. "
The price is AU$76
includes taxes & fees
13 July - 14 July
Hotel Ojos del Rio

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1012)
"We truly enjoyed our stay at this hotel and will be back in future! "
The price is AU$339
includes taxes & fees
1 Aug - 2 Aug
JW Marriott Panama

Residence Inn by Marriott Panama City

4.0 star property
9.0 out of 10, Wonderful, (482)
"Great location clean "
The price is AU$226
includes taxes & fees
19 July - 20 July
Residence Inn by Marriott Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa Clara

Santa Clara awaits: its natural setting, monuments, history and more!

Frequently asked questions

What's the best place to stay in Santa Clara?

Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Dreams Playa Bonita Panama - All Inclusive and Sheraton Grand Panama. See all available top hotels, or vacation rentals in Santa Clara.

What are some of the best holiday rentals that Santa Clara has to offer?

Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces: This holiday home rental outside of Santa Clara offers a balcony, a selection of games and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 6 bedrooms, as well as a kitchen with a fridge, a stovetop and a microwave, so that you can cook with friends or family. See all vacation rentals in Santa Clara.

If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.

What are some accommodation options with pools in Santa Clara?

Hotel Riu Plaza Panama: 4-star hotel located near Avenida Balboa. Features 3 restaurants, an outdoor pool and free Internet. JW Marriott Panama and Aloft Panama are two additional hotels that offer an on-site pool. View all hotels with pools in Santa Clara.

What is staying in Santa Clara like?

Visitors can enjoy all that Santa Clara has to offer, including its monuments. A top sight in the area is Albrook Shopping Mall. There are 1453 hotels and other accommodation options in the surrounding area. Find out more about Santa Clara.

What should I do while I'm visiting Santa Clara?

A favourite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall in the area. Take a look at what more there is to see and do in Expedia's Santa Clara guide.

What's the weather like in Santa Clara?

The hottest months are usually April and March, with an average temperature of 26°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Santa Clara are July, August, November and October, with each month seeing an average of 283 mm of rainfall.