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Check prices for these dates

Tonight
16 Feb - 17 Feb
Tomorrow
17 Feb - 18 Feb
Next weekend
21 Feb - 23 Feb
In two weeks
28 Feb - 2 Mar

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Top hotels and accommodation in Santa Cruz

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Learn more about Santa Cruz

Head to sights like Pacaya-Samiria National Reserve and Huallaga River as you discover Santa Cruz.

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Frequently asked questions

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

What should I see while I'm in Santa Cruz?

The picturesque setting of Pacaya-Samiria National Reserve and Huallaga River exemplify the area's natural beauty. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.

What's the seasonal weather like in Santa Cruz?

The hottest months are usually September and October, with an average temperature of 26°C, while the coldest months are July and June, with an average of 25°C. The rainiest months in Santa Cruz are March, April, February and May, with each month seeing an average of 337 mm of rainfall.