Santa Cruz Travel Guide

Tourist Guide

San Lorenzo Cathedral showing a garden
Santa Cruz which includes a city
San Lorenzo Cathedral featuring heritage architecture and heritage elements
Santa Cruz featuring a city
San Lorenzo Cathedral
Experience Bolivia as the locals see it in the country’s busiest city, where the museums, public squares and churches give you a glimpse into their everyday lives.

Although Santa Cruz de la Sierra, more commonly known as Santa Cruz, is the most populous city in Bolivia, it is still relatively unknown by tourists. Sample an authentic Bolivian lifestyle in this busy city. Visit Santa Cruz’s churches and museums for an insight into the region’s history or simply soak up the atmosphere over a drink with the friendly locals.

Explore a city that started out in a totally different location. Santa Cruz was founded in 1561, but had to move west after several decades of fending off attacks. Visit the historic heart of the city in Plaza 24 de SeptiembreOpens in a new window, which is more than 400 years old, to relax with the locals, who are known as “cruceños.”

The most distinctive attraction in the city is San Lorenzo CathedralOpens in a new window, which is immediately recognizable for its red-brick frontage featuring two clock towers standing on either side of a pediment. The cathedral hosts the Museum of Sacred Art, with exhibits that display religious icons and Jesuit relics. Climb to the top of the clock tower for panoramic views of the city.

Wander around the Parque Arenal, a green space in the middle of the city. The park has a boating lagoon and the Museo Etnofolklorico (Santa Cruz Ethnographic Museum). Other museums in the city include the Guarani Museum, which examines the culture of the indigenous Guarani people, and the National History Museum.

Take children to the Zoological Gardens, where they can meet animals from around Bolivia. The zoo’s llamas and sloths are always popular with younger visitors.

Fly into the busiest airport in Bolivia, Viru Viru International Airport. Flights arrive here from destinations in both Bolivia and cities in North and South America. Some operators even fly here from cities in Europe, such as Madrid.

Santa Cruz de la Sierra is located in the lowlands of Bolivia in the east of the country, which means that rainfall is high during the summer months around January. Come during the high season, between May and October, for more dependable weather but higher prices.

Where to stay in Santa Cruz

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Hamacas

When in Hamacas, you can plan a visit to Las Brisas Shopping Center and Santa Cruz Zoo, some noteworthy sights in the nearby area.

Hamacas
Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra Hotel
5 out of 5
4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz
The price is AU$177 per night from 20 Apr to 21 Apr
AU$177
includes taxes & fees
20 Apr - 21 Apr
Stay at this 5-star luxury hotel in Santa Cruz. Enjoy free parking, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff and the property ...
9/10 Wonderful! (187 reviews)
"Everything was amazing! Great staff and amazing service!"

Reviewed on 25 Mar. 2025

Marriott Santa Cruz de la Sierra Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 out of 5
Ave. San Martin, #455, Santa Cruz
Fully refundable
The price is AU$191 per night from 27 Apr to 28 Apr
AU$191
includes taxes & fees
27 Apr - 28 Apr
Stay at this 3.5-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (312 reviews)
"Amazing"

Reviewed on 30 Mar. 2025

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Sun Hotel
Sun Hotel
3.5 out of 5
Av. Banzer Km 13, Aeropuerto Internacional Viru Viru, Santa Cruz, Santa Cruz
The price is AU$171 per night from 16 Apr to 17 Apr
AU$171
includes taxes & fees
16 Apr - 17 Apr
Stay at this 3.5-star business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Play Land Amusement Park is ...
8.2/10 Very Good! (288 reviews)
"Great place"

Reviewed on 13 Apr. 2025

Sun Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Apart Hotel Premium Suites Santa Cruz
Apart Hotel Premium Suites Santa Cruz
3.5 out of 5
Calle Las Begonias Nro 45, a 1 cuadra de la Av. San Martin, Santa Cruz
Stay at this 3.5-star business-friendly aparthotel in Santa Cruz. Enjoy free WiFi, free parking, and room service. Popular attractions Patio Design LifeStyle ...
8.6/10 Excellent! (84 reviews)
"Good location, spacious apartment, good stay overall"

Reviewed on 12 Oct. 2020

Apart Hotel Premium Suites Santa Cruz
Premium Suites Deluxe Aparthotel Equipetrol
Premium Suites Deluxe Aparthotel Equipetrol
3.5 out of 5
Calle Las Azucenas No. 127, 1 block from San Martin Avenue, Santa Cruz, Santa Cruz
Stay at this 3.5-star business-friendly aparthotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Patio Design ...
9/10 Wonderful! (69 reviews)
"Very clean!"

Reviewed on 12 Jan. 2025

Premium Suites Deluxe Aparthotel Equipetrol
Buena Vista Rental House
Buena Vista Rental House
3 out of 5
Santa Cruz
Stay at this 3-star apartment in Santa Cruz. Enjoy parking (surcharge), a garden, and air conditioning. Popular attractions Patio Design LifeStyle Center and ...
Buena Vista Rental House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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