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Check Santa Isabel do Rio Negro hotel prices

Tonight
25 Nov - 26 Nov
Tomorrow night
26 Nov - 27 Nov
This weekend
29 Nov - 1 Dec
Next weekend
6 Dec - 8 Dec

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Top hotels and accommodation in Santa Isabel do Rio Negro

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Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.
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Frequently asked questions

If I need to cancel my hotel reservation in Santa Isabel do Rio Negro, will I receive a refund?

Yes! The majority of room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If your reservation is non-refundable, you might be able to still cancel and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Isabel do Rio Negro.

What should I do while I'm visiting Santa Isabel do Rio Negro?

A favourite place to visit is Pico da Neblina. Take a look at what more there is to see and do in Expedia's Santa Isabel do Rio Negro guide.

What's the seasonal weather in Santa Isabel do Rio Negro?

The hottest months are usually September and October, with an average temperature of 27°C, while the coldest months are July and June, with an average of 26°C. The rainiest months in Santa Isabel do Rio Negro are May, April, March and June, with each month seeing an average of 407 mm of rainfall.