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Top hotels and accommodation in Santana

N Guembú Nature Resort
3.0 star property
8.0 out of 10, Very good, (5)
"Tolle Unterkunft, leider jedoch ein wenig in die Jahre gekommen. Bitte nehmt ausreichend Kleingeld mit, da nach jeder Mahlzeit bezahlt wird und nicht gewechselt werden kann. "
The price is AU$130
includes taxes & fees
22 Nov - 23 Nov
N Guembú Nature Resort
CAMPISMO PRAIA GRANDE
1.0 star property
The price is AU$97
includes taxes & fees
22 Nov - 23 Nov
CAMPISMO PRAIA GRANDE
Pool and Beach Villa in Santana
Pool and Beach Villa in Santana
Praia Inhame Eco-Lodge
2.0 star property
8.8 out of 10, Excellent, (26)
"We had a great stay at Inhame. After a rather scary drive down south through fog, rain, potholes wet palm plantations at dusk, the lodge’s sign of entering a stress-free zone was only too welcome. Rides to the Ilha Rolas and the walk to Praia Vanha arranged easily. Rhe breakfast excellent and all very clean."
The price is AU$192
includes taxes & fees
7 Dec - 8 Dec
Praia Inhame Eco-Lodge
Jo's Nature Cabin Santana
Jo's Nature Cabin Santana
CHALET 19_ An inclusive tourism, an experience for life!
The price is AU$123
includes taxes & fees
22 Nov - 23 Nov
CHALET 19_ An inclusive tourism, an experience for life!
endless horizon - Cozy house in charming Santana with WiFi
The price is AU$210
includes taxes & fees
7 Dec - 8 Dec
endless horizon - Cozy house in charming Santana with WiFi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Beautiful view of the beach with palm trees

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Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

Where is the best place to stay in Santana?

Based on our traveller data, Roça Santo António Ecolodge Hotel is one of the top choices for your stay. This hotel offers free breakfast and a restaurant. Pool and Beach Villa in Santana is another good choice for your visit. See all available top hotels, or vacation rentals in Santana.

What are some of the best holiday rentals that Santana has to offer?

Endless horizon - Cozy house in charming Santana with WiFi: This highly rated holiday home rental in Santana offers a selection of books and WiFi to help you feel comfortable in your new surroundings. Kitchen amenities include a stovetop, a coffee maker and kitchenware. See all vacation rentals in Santana.

If I need to cancel my hotel reservation in Santana, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santana.

What's the best family accommodation in Santana?

Roça Santo António Ecolodge Hotel is a hotel with a children's pool and a restaurant, and it's a top choice on Expedia for families. Find more child-friendly accommodations in Santana.

What are some accommodation options with pools in Santana?

Roça Santo António Ecolodge Hotel is a top hotel with a children's pool, an outdoor pool and free buffet breakfast. View all hotels with pools in Santana.

How is it to stay in Santana?

Those travelling to Santana will definitely enjoy the sights to see and things to do. In Santana, there are 5 hotels and other accommodation options to choose from. Find out more about Santana.

What are the top places to visit in Santana?

Places to visit in the wider area include Cathedral of São Tomé, Amelia Lagoon and Pico São Tomé. You'll also find Paroquia da Santissima Trindade and Estadio Nacional 12 de Julho in the area. Take a look at what more there is to see and do in Expedia's Santana guide.

What's the weather like in Santana?

The hottest months are usually March and April, with an average temperature of 28°C, while the coldest months are July and August, with an average of 25°C. The rainiest months in Santana are November, October, December and April, with each month seeing an average of 249 mm of rainfall.