Search Santee hotels

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Property class

Top hotels and accommodation in Santee

Fairfield Inn & Suites by Marriott Santee

2.5 star property
9.8 out of 10, Exceptional, (1000)
"Excellent overnight stay"
The price is AU$221
includes taxes & fees
17 Aug - 18 Aug
Fairfield Inn & Suites by Marriott Santee

Hampton Inn Santee-I-95

2.5 star property
9.6 out of 10, Exceptional, (1000)
"Great stay"
The price is AU$225
includes taxes & fees
17 Aug - 18 Aug
Hampton Inn Santee-I-95

SureStay Hotel by Best Western Manning

2.5 star property
8.6 out of 10, Excellent, (1001)
"The hotel was a great stop on our vacation. It was a nice stay.."
The price is AU$194
includes taxes & fees
11 Aug - 12 Aug
SureStay Hotel by Best Western Manning

Holiday Inn Santee by IHG

3.0 star property
8.2 out of 10, Very good, (924)
"The staff were great from checking in to checking out. The room was very clean and well kept. Would highly recommend. "
The price is AU$220
includes taxes & fees
10 Aug - 11 Aug
Holiday Inn Santee by IHG

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very good, (1316)
"Nice room, nice staff, nice breakfast"
The price is AU$128
includes taxes & fees
11 Aug - 12 Aug
Baymont by Wyndham Santee

Tru By Hilton Santee

2.5 star property
9.2 out of 10, Wonderful, (496)
"Staff was wonderful at check-in. Property was well lit."
The price is AU$172
includes taxes & fees
17 Aug - 18 Aug
Tru By Hilton Santee

Hampton Inn & Suites Orangeburg

2.5 star property
9.4 out of 10, Exceptional, (721)
"Bed was comfortable and the front desk staff wonderful "
The price is AU$231
includes taxes & fees
31 Aug - 1 Sept
Hampton Inn & Suites Orangeburg

Best Western Plus Santee Inn

2.5 star property
8.8 out of 10, Excellent, (1001)
"Nice pool and great breakfast. The staff was accommodating to our requests, friendly, and attentive."
The price is AU$195
includes taxes & fees
21 Aug - 22 Aug
Best Western Plus Santee Inn

Hampton Inn Manning

2.5 star property
8.4 out of 10, Very good, (952)
"Room was clean, a nice breakfast was provided each morning which was great. I would stay there again."
The price is AU$188
includes taxes & fees
4 Sept - 5 Sept
Hampton Inn Manning

Comfort Inn & Suites Santee

2.5 star property
8.0 out of 10, Very good, (1000)
"Good place to stay"
The price is AU$172
includes taxes & fees
17 Aug - 18 Aug
Comfort Inn & Suites Santee

Travelodge by Wyndham Santee

2.0 star property
7.0 out of 10, Good, (645)
"Very nice anf clean"
The price is AU$105
includes taxes & fees
21 Aug - 22 Aug
Travelodge by Wyndham Santee

Super 8 by Wyndham Santee

2.0 star property
6.8 out of 10, (428)
"It's a very quiet hotel. My room was very spacious. And the bed was very comfortable."
The price is AU$128
includes taxes & fees
10 Aug - 11 Aug
Super 8 by Wyndham Santee

Red Roof Inn Santee

2.0 star property
6.6 out of 10, (621)
"it was clean and the staff was friendly"
The price is AU$111
includes taxes & fees
10 Aug - 11 Aug
Red Roof Inn Santee

Quality Inn & Suites

2.5 star property
6.0 out of 10, (421)
"The Lobby was beautiful. The atmosphere was very pleasant."
The price is AU$101
includes taxes & fees
17 Aug - 18 Aug
Quality Inn & Suites

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (531)
"Nice clean friendly "
The price is AU$135
includes taxes & fees
10 Aug - 11 Aug
Ramada by Wyndham Santee I-95

Econo Lodge

2.0 star property
6.4 out of 10, (309)
"No towels and dirty sink."
The price is AU$101
includes taxes & fees
21 Aug - 22 Aug
Econo Lodge

Motel 6 Saint George, SC – I-95

2.0 star property
6.6 out of 10, (169)
"great team"
The price is AU$109
includes taxes & fees
12 Aug - 13 Aug
Motel 6 Saint George, SC – I-95

Bells Marina & Resort

2.5 star property
8.6 out of 10, Excellent, (73)
"Had a great stay"
Bells Marina & Resort

Holiday Inn Express & Suites Orangeburg by IHG

2.5 star property
8.6 out of 10, Excellent, (767)
"Staff is always so friendly, very clean and great atmosphere "
The price is AU$179
includes taxes & fees
24 Aug - 25 Aug
Holiday Inn Express & Suites Orangeburg by IHG

Fairfield Inn by Marriott Orangeburg

2.5 star property
8.4 out of 10, Very good, (625)
"It was a little loud due to a family with small children, but other than that good stay"
The price is AU$159
includes taxes & fees
17 Aug - 18 Aug
Fairfield Inn by Marriott Orangeburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near top Santee attractions

Santee State Park

Santee State Park

You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savour the top-notch restaurants.

Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campsites.

Top Santee Hotel Reviews

Frequently asked questions

Where is the best place for a stay in Santee?

Fairfield Inn & Suites by Marriott Santee is a favourite property for Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on traveller reviews include Hampton Inn Santee-I-95 and Holiday Inn Santee by IHG. See all available top hotels, or vacation rentals in Santee.

What are some of the best holiday rentals that Santee has to offer?

Wyndham Vacation Resorts Lake Marion: This highly rated holiday home rental in Santee is equipped with an outdoor pool, free WiFi and a TV to help you feel comfortable during your stay. It has 3 bedrooms, as well as a kitchen with a full-sized fridge, a dishwasher and a stovetop, so that you can cook with friends or family. Some other homes for rent in Santee include Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95! and Private Dock + Pool Table: Lake Marion Getaway. See all vacation rentals in Santee.

If I need to cancel my hotel reservation in Santee, will I receive a refund?

Yes, you'll find most room reservations are fully refundable as long as you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, you might be able to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.

What's the best place to stay on a budget in Santee?

Based on reviews, Baymont by Wyndham Santee is a popular hotel for our travellers who want a more economical choice, and features free breakfast and free Wi-Fi. View all budget hotels in Santee.

What's the best family accommodation in Santee?

Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another good option for your stay with the kids. Find more child-friendly accommodations in Santee.

What is the top LGBTQ-friendly accommodation in Santee?

Fairfield Inn & Suites by Marriott Santee is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn Santee-I-95 and Holiday Inn Santee by IHG are two other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santee.

What's the best dog-friendly hotel in Santee?

Baymont by Wyndham Santee is a top hotel for people travelling with their pets, and offers concierge services and free WiFi for its human guests. Two other good options for you and your pet include Tru By Hilton Santee and Fairfield Inn & Suites by Marriott Santee. See more pet-friendly hotel accommodations in Santee.

What's the best accommodation for a golf trip to Santee?

Holiday Inn Santee by IHG is a top hotel that has an adjacent golf course and features free WiFi. Other good options to stay near a golf course include Ramada by Wyndham Santee I-95 and Super 8 by Wyndham Santee. Visit Santee Cooper Country Club or Santee National Golf Club to perfect your golf swing. See more golf hotels in Santee.

What are some accommodation options with pools in Santee?

Fairfield Inn & Suites by Marriott Santee is a top hotel with a pool, free buffet breakfast and free WiFi. Quality Inn & Suites is an additional hotel with an on-site pool. View all hotels with pools in Santee.

What is the best spa hotel in Santee?

Fairfield Inn & Suites by Marriott Santee is a top spa hotel featuring an outdoor pool and a 24-hour fitness centre. See all spa hotels in Santee.

What is staying in Santee like?

Families will find child-friendly activities in Santee, and visitors give high marks for the top-notch restaurants. This welcoming city also attracts tourists with its golf courses and cafes. In Santee, there are 128 hotels and other accommodation options to choose from. Find out more about Santee.

What are the top places to visit in Santee?

Favourite places to visit include Santee Cooper Country Club, Santee National Golf Club and Santee State Park. A couple of additional sights to add to your itinerary are Lake Marion and Santee Town Hall. Take a look at what more there is to see and do in Expedia's Santee guide.

What's the seasonal weather like in Santee?

The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Santee is 1397 mm.