Search Santiago Sur hotels

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Property class

Top hotels and accommodation in Santiago Sur

Cabañas Palma Real

3.0 star property
The price is AU$116
includes taxes & fees
21 July - 22 July
Cabañas Palma Real

Hotel Mykonos Panama

3.5 star property
8.8 out of 10, Excellent, (520)
"Great location and service."
The price is AU$144
includes taxes & fees
21 July - 22 July
Hotel Mykonos Panama

Casa Morrillo

2.5 star property
6.0 out of 10, (2)
"Amazing location. Great staff and owners."
The price is AU$163
includes taxes & fees
21 July - 22 July
Casa Morrillo

Punta Duarte Garden Inn

3.0 star property
9.2 out of 10, Wonderful, (35)
"The hotel is located on a beautiful bluff overlooking the ocean. Our only negative review is the 2 mile dirt road to get to the beautiful location. "
The price is AU$167
includes taxes & fees
21 July - 22 July
Punta Duarte Garden Inn

Hotel Galería

3.0 star property
8.4 out of 10, Very good, (189)
"SC"
The price is AU$108
includes taxes & fees
22 July - 23 July
Hotel Galería

Hotel Gran David

3.5 star property
8.4 out of 10, Very good, (313)
"Great place to stay for the night on the way to Boquete from Panama City. "
Hotel Gran David

Hotel Hibiscus Garden / Jardin De Papos

2.5 star property
6.4 out of 10, (14)
"The online 1-star rating is not really justified. Although basic, this place is worth the $55 fee. The Hotels.com experience is to be avoided, they overcharged on the rate. The room was basic, the bed below average, but seeing the many species and number of sea birds in the early morning is a treat. The dirt driveway to the site is a biet of a pain."
The price is AU$68
includes taxes & fees
21 July - 22 July
Hotel Hibiscus Garden / Jardin De Papos

Kooteja Santa Catalina KAÏSA

3.0 star property
8.0 out of 10, Very good, (1)
"The system to get in the cabin is pretty clever, and the place looked nice. Yet, I would have appreciated instructions on where to leave the money and also if the grass around the cabin was lower or cut. "
The price is AU$134
includes taxes & fees
29 July - 30 July
Kooteja Santa Catalina KAÏSA

Hotel y Restaurante Mama Ines

3.0 star property
8.6 out of 10, Excellent, (15)
"Location is everything here. Property is quaint but lovely. Staff are very nice and helpful. Close to everything. Dining options in the area (walkable) are awesome. Wi-Fi and water pressure could both be better. Water pressure is the thing that lowered the review. But I would go back in a heartbeat. "
Hotel y Restaurante Mama Ines

Bambuda Santa Catalina

2.5 star property
9.4 out of 10, Exceptional, (39)
"Great place to stay while visiting area and Coiba National Park"
Bambuda Santa Catalina

Hotel Santa Catalina Panama

3.0 star property
9.0 out of 10, Wonderful, (124)
"The best and friendliest staff, excellent food, beautiful pool!!"
The price is AU$219
includes taxes & fees
2 Aug - 3 Aug
Hotel Santa Catalina Panama

Villa Coco

2.5 star property
9.2 out of 10, Wonderful, (47)
"Great customer service - beautiful property "
The price is AU$220
includes taxes & fees
17 Aug - 18 Aug
Villa Coco

La Chamba Surf House

3.0 star property
The price is AU$59
includes taxes & fees
25 July - 26 July
La Chamba Surf House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Santiago Sur

Check out Mariato Beach—just one of the sights to explore around Santiago Sur.

Top Santiago Sur Hotel Reviews

Frequently asked questions

What's the best place to stay in Santiago Sur?

Based on our traveller data, Cabañas Palma Real is one of the top choices for your stay. This cabin offers an outdoor pool and free parking. Other good choices for your visit to the area are Hotel Gran David and Hotel Mykonos Panama. See all available top hotels, or vacation rentals in Santiago Sur.

What are some of the best holiday rentals that Santiago Sur has to offer?

Charming 1-Bedroom Beachfront Hotel With Pool: This holiday home rental outside of Santiago Sur has air conditioning and WiFi to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Santiago Sur.

If I need to cancel my hotel reservation in Santiago Sur, will I receive a refund?

Yes! Most hotel room reservations are fully refundable if you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santiago Sur.

What is staying in Santiago Sur like?

Travellers to Santiago Sur will find plenty to explore and enjoy. There are 54 hotels and other accommodation options in the surrounding area. Find out more about Santiago Sur.

What should I see while I'm in Santiago Sur?

Places to visit in the wider area include Mariato Beach, Torio Beach and Lagartero Beach. Additionally, you'll find Torio Falls in the area. Take a look at what more there is to see and do in Expedia's Santiago Sur guide.

What's the seasonal weather like in Santiago Sur?

The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and December, with an average of 25°C. The rainiest months in Santiago Sur are October, August, June and November, with each month seeing an average of 447 mm of rainfall.