Santo Spirito Holidays

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Your Santo Spirito Holiday

Walking, views and culture are just some of the things waiting for you when you book a Santo Spirito holiday package. Whether you're chasing relaxation, adventure or something else, this residential neighbourhood is where you can find it. Your trip to Santo Spirito wouldn't be complete without stopping by leading attractions nearby such as Piazza Santo Spirito, Santo Spirito Basilica and Brancacci Chapel. No matter what your dream Santo Spirito holiday looks like, you can make it a reality with Expedia.

Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.
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Our guide on where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
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Duomo

5 out of top 10 points of interest in this area
4.5/5(143 area reviews)

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Via de' Calzaiuoli while you're exploring the neighbourhood.

Find hotel + flight trips in Duomo

Our pick of the best Santo Spirito Hotel Deals

UNAHOTELS Vittoria Firenze
UNAHOTELS Vittoria Firenze
4 out of 5
Via Pisana 59, Florence, FI
Fully refundableReserve now, pay when you stay
The price is AU$164 per night from 13 Dec to 14 Dec
AU$164
includes taxes & fees
13 Dec - 14 Dec
8.4/10 Very Good! (985 reviews)
"Reception"

Reviewed on 13 Nov. 2024

UNAHOTELS Vittoria Firenze
Hotel Horto Convento
Hotel Horto Convento
4 out of 5
Viale Ariosto, 13, Florence
Fully refundableReserve now, pay when you stay
The price is AU$209 per night from 15 Dec to 16 Dec
AU$209
includes taxes & fees
15 Dec - 16 Dec
9.6/10 Exceptional! (455 reviews)
"The hotel was great and clean. Staff were very welcoming, helpful, and kind. We received a couple of restaurant suggestions in the area when we asked for a more local experience. We were also given a quick guide on what to see around the city. Overall great experience."

Reviewed on 20 Nov. 2024

Hotel Horto Convento
Foresteria Valdese di Firenze - Casa per Ferie
Foresteria Valdese di Firenze - Casa per Ferie
Via dei Serragli 49, Florence
Fully refundableReserve now, pay when you stay
The price is AU$150 per night from 1 Dec to 2 Dec
AU$150
includes taxes & fees
1 Dec - 2 Dec
8.6/10 Excellent! (105 reviews)
"Our room was large, and the staff was friendly and helpful. It is a quick walk over the bridge to the heart of Florence, and there are many good dining options nearby."

Reviewed on 31 Oct. 2024

Foresteria Valdese di Firenze - Casa per Ferie
See all 450 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

How much does a Santo Spirito holiday package cost?
From just . Yes, you read that right. Our Santo Spirito packages are the best way to make your dollar go further. Bundle your favourite hotels, flights and rental car and explore this wonderful destination.
How do I get a cheap travel package to Santo Spirito?
If you love scoring a bargain, bundle your bookings into a Santo Spirito holiday package. Whether you need hotels, flights, activities or rental cars, you can book everything in one place. You’ll have endless choice at your fingertips as well. Expedia has more than 550 partner airlines and 1 000 000 hotels across the globe to choose from. Fly with who you want, stay in a place you like and save precious dollars — now that’s the ideal getaway!
What are the top hotels in Santo Spirito?
Reserve a room at Sweet Home Campuccio, 2 Double Bedrooms In San Frediano. It’s one of this area’s most sought-after hotels. Another well-known option in Santo Spirito is Residenza Oltrarno, An Elegant Apartment In The Historic Centre Of Florence.
How far in advance should I book my Santo Spirito holiday?
To score cheap prices, book as soon as you can. Airlines typically release tickets, along with some of the lowest fares, up to a year in advance. Hotels, activities and car rental should also be booked early to avoid disappointment. If you were hoping for a last-minute getaway in Santo Spirito, there are always lots of great deals on Expedia. Check them out now!
What does an Expedia Santo Spirito travel package include?
Rental cars, flights and hotels, or any combination of the three — it’s totally up to you. Whether you’re headed to Santo Spirito with the entire family or enjoying a solo break, there’s a bundle to match every budget and style. Once you’ve made your booking, why not add on a couple of tours as well?
What should I know before booking a Santo Spirito travel package?
Locking in all the parts of your trip together is one of the best ways to save. Combine car rentals, airfares and hotels into a neat little package. But you’re not restricted to hotels. Expedia features all sorts of properties, including holiday homes like oceanfront condos and city residences. The list goes on!
Can I choose my airline with a Santo Spirito Expedia holiday package?
Yes — and it’s simple too. Expedia has access to more than 550 partner airlines all over the world. Our holiday packages give you the freedom to pick from available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Santo Spirito holiday package?
If your holiday plans in Santo Spirito have been upended, it’s a relief to know that it is possible to cancel your booking. If you made your booking within the last 24 hours, you may be eligible for a refund. If your booking is older than that, your airline, hotel or car rental company may charge a fee. For more details, check our Customer Service Portal.

Discover the most popular places to visit in Santo Spirito

Piazza del Carmine

You can learn about the history of San Frediano with a trip to Piazza del Carmine. Amble around this vibrant area's riverfront or experience its acclaimed art galleries.

Piazza del Carmine

Activities

Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine

Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine

AU$53
Per adult
74% of travellers recommend
Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine
Pastamania - Pasta making class

Pastamania - Florence Pasta Making Class

AU$91
Per adult
100% of travellers recommend
Pastamania - Florence Pasta Making Class
Florence: Santa Monaca Church Italian Opera Concert Ticket

Florence: Santa Monaca Church Italian Opera Concert Ticket

AU$41
Per adult
100% of travellers recommend
Florence: Santa Monaca Church Italian Opera Concert Ticket
See all activities in Florence
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.