Santo Spirito Holidays from AU$3,075

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Your Santo Spirito Holiday

Walking, views and culture are just some of the things waiting for you when you book a Santo Spirito holiday package. Whether you're chasing relaxation, adventure or something else, this residential neighbourhood is where you can find it. Your trip to Santo Spirito wouldn't be complete without stopping by leading attractions nearby such as Piazza Santo Spirito, Santo Spirito Basilica and Brancacci Chapel. No matter what your dream Santo Spirito holiday looks like, you can make it a reality with Expedia.

Top Holiday Package Deals in Santo Spirito

Price found within the past 48 hours. Click for updated prices.
Eurostars Florence Boutique

Eurostars Florence Boutique

4 out of 5
Historic Centre of Florence
per person
5 Sept - 11 Sept
found 1 day ago
Return flight included
Melbourne (MEL) to Florence (FLR)
8.6/10 Excellent! (464 reviews)
Nice hotel, very clean, a little far from main attractions, but in general I really like it

Reviewed on 14 Jul. 2025

The Moon Boutique Hotel & Spa

The Moon Boutique Hotel & Spa

4 out of 5
Historic Centre of Florence
per person
5 Sept - 11 Sept
found 1 day ago
Return flight included
Melbourne (MEL) to Florence (FLR)
9.6/10 Exceptional! (462 reviews)
Hands down the best place we have stayed. They accommodated to go breakfasts for our tours, arranged taxis, made cappuccino when we were heading out the door. Wonderful experience

Reviewed on 6 Jun. 2025

LHP River Club

LHP River Club

5 out of 5
Santa Croce
per person
30 Sept - 6 Oct
found 23 hours ago
Return direct flight included
Sydney (SYD) to Florence (FLR)
No reviews
Villa Tolomei Hotel & Resort

Villa Tolomei Hotel & Resort

5 out of 5
Oltrarno
per person
30 Sept - 6 Oct
found 23 hours ago
Return direct flight included
Sydney (SYD) to Florence (FLR)
8.8/10 Excellent! (382 reviews)
It is such a beautiful property and our apartment was clean and comfortable. Ate at the lovely restaurant one nigh and had take out the second. The breakfast was fantastic, so delicious with many options. The staff were so friendly and helpful.

Reviewed on 21 Jul. 2025

Dimora Palanca Boutique & SPA

Dimora Palanca Boutique & SPA

5 out of 5
Historic Centre of Florence
per person
5 Sept - 11 Sept
found 1 day ago
Return flight included
Melbourne (MEL) to Florence (FLR)
9.4/10 Exceptional! (42 reviews)
The staff went out of their way to be helpful with all queries

Reviewed on 21 Jun. 2025

Our guide on where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
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Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

Our pick of the best Santo Spirito Hotel Deals

UNA HOTELS Vittoria Firenze

UNA HOTELS Vittoria Firenze

4 out of 5
Via Pisana 59, Florence, FI
Fully refundableReserve now, pay when you stay
The price is AU$206 per night from 27 July to 28 July
AU$206
27 July - 28 July
includes taxes & fees
8.4/10 Very Good! (986 reviews)
"It was average really. Needs to be updated in the rooms blobby area and outside was very nice"

Reviewed on 31 May 2025

UNA HOTELS Vittoria Firenze
Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13, Florence, FI
Fully refundableReserve now, pay when you stay
The price is AU$278 per night from 21 Aug to 22 Aug
AU$278
21 Aug - 22 Aug
includes taxes & fees
9.6/10 Exceptional! (541 reviews)
"Staff were very helpful and professional. Speaking English was not a problem. The breakfast buffet had a lot fresh food, fruit and pastries to choose from"

Reviewed on 7 Jul. 2025

Hotel Horto Convento
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r, Florence, FI
9.2/10 Wonderful! (1,005 reviews)
"Great little place in the middle of old town. Nice to have a kitchen. Very walkable location. Staff was wonderful, with recommendations and very helpful with taxi transportation."

Reviewed on 23 Jul. 2025

Get rates
Palazzo Mannaioni Suites
See all 469 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

How much does a Santo Spirito holiday package cost?
From just AU$3,075. Yes, you read that right. Our Santo Spirito packages are the best way to make your dollar go further. Bundle your favourite hotels, flights and rental car and explore this wonderful destination.
How do I get a cheap travel package to Santo Spirito?
If you love scoring a bargain, bundle your bookings into a Santo Spirito holiday package. Whether you need hotels, flights, activities or rental cars, you can book everything in one place. You'll have endless choice at your fingertips as well. Expedia has more than 550 partner airlines and 1 000 000 hotels across the globe to choose from. Fly with who you want, stay in a place you like and save precious dollars — now that's the ideal getaway!
What are the top hotels in Santo Spirito?
Reserve a room at Sweet Home Campuccio, 2 Double Bedrooms In San Frediano. It's one of this area's most sought-after hotels. Another well-known option in Santo Spirito is Residenza Oltrarno, An Elegant Apartment In The Historic Centre Of Florence.
How far in advance should I book my Santo Spirito holiday?
To score cheap prices, book as soon as you can. Airlines typically release tickets, along with some of the lowest fares, up to a year in advance. Hotels, activities and car rental should also be booked early to avoid disappointment. If you were hoping for a last-minute getaway in Santo Spirito, there are always lots of great deals on Expedia. Check them out now!
What does an Expedia Santo Spirito travel package include?
Rental cars, flights and hotels, or any combination of the three — it's totally up to you. Whether you're headed to Santo Spirito with the entire family or enjoying a solo break, there's a bundle to match every budget and style. Once you've made your booking, why not add on a couple of tours as well?
What should I know before booking a Santo Spirito travel package?
Locking in all the parts of your trip together is one of the best ways to save. Combine car rentals, airfares and hotels into a neat little package. But you're not restricted to hotels. Expedia features all sorts of properties, including holiday homes like oceanfront condos and city residences. The list goes on!
Can I choose my airline with a Santo Spirito Expedia holiday package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines all over the world. Our holiday packages give you the freedom to pick from available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Santo Spirito holiday package?
If your holiday plans in Santo Spirito have been upended, it's a relief to know that it is possible to cancel your booking. If you made your booking within the last 24 hours, you may be eligible for a refund. If your booking is older than that, your airline, hotel or car rental company may charge a fee. For more details, check our Customer Service Portal.

Discover the most popular places to visit in Santo Spirito

Piazza del Carmine

You can learn about the history of Florence with a trip to Piazza del Carmine. Amble around this vibrant area's riverfront or experience its acclaimed art galleries.

Piazza del Carmine

Activities

Florence: Santa Monaca Church Italian Opera Concert Ticket

Florence: Santa Monaca Church Italian Opera Concert Ticket

AU$53
per adult
100% of travellers recommend
Florence: Santa Monaca Church Italian Opera Concert Ticket
Pastamania - Florence Pasta Making Class

Pastamania - Florence Pasta Making Class

AU$126
per adult
100% of travellers recommend
Pastamania - Florence Pasta Making Class
Florence Sunset Wine & Food Tour

Florence Sunset Wine & Food Tour

AU$187
per adult
100% of travellers recommend
Florence Sunset Wine & Food Tour
See all activities in Florence
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.