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Your Santo Spirito Holiday
Walking, views and culture are just some of the things waiting for you when you book a Santo Spirito holiday package. Whether you're chasing relaxation, adventure or something else, this residential neighbourhood is where you can find it. Your trip to Santo Spirito wouldn't be complete without stopping by leading attractions nearby such as Piazza Santo Spirito, Santo Spirito Basilica and Brancacci Chapel. No matter what your dream Santo Spirito holiday looks like, you can make it a reality with Expedia.
Our guide on where to stay in Santo Spirito
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Via de' Calzaiuoli while you're exploring the neighbourhood.
Our pick of the best Santo Spirito Hotel Deals
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Discover the most popular places to visit in Santo Spirito
Piazza del Carmine
You can learn about the history of San Frediano with a trip to Piazza del Carmine. Amble around this vibrant area's riverfront or experience its acclaimed art galleries.