
Uptown - Upper Duval Holidays
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Your Uptown - Upper Duval Holiday
Take the hassle out of planning your next escape by booking an Uptown - Upper Duval holiday package. Immerse yourself in the sights and sounds of this unique neighbourhood and enjoy what it has to offer. Some leading nearby attractions to check out during your trip to Uptown - Upper Duval include Ernest Hemingway Home and Museum, Audubon House and Tropical Gardens and Mallory Square. No matter your travel plans or the size of your budget, booking the ultimate Uptown - Upper Duval holiday is simple with Expedia.
Our guide on where to stay in Uptown - Upper Duval

Old Town Key West
While visiting Old Town Key West, you might make a stop by sights like Duval Street and Saint Mary Star of the Sea.
Our pick of the best Uptown - Upper Duval Hotel Deals

Southernmost Beach Resort and Guesthouses
Reviewed on 18 Aug. 2025

The Reach Key West, Curio Collection by Hilton
Reviewed on 10 Aug. 2025

The Southernmost Inn - Adults Only
Reviewed on 16 Aug. 2025
Frequently asked questions
Discover the most popular places to visit in Uptown - Upper Duval

Southernmost Point
Snap a memorable photograph from the edge of North America at this monumental landmark.

Key West Butterfly and Nature Conservatory
Encounter hundreds of butterflies in a tropical rainforest setting, butterfly-friendly birds and an indoor waterfall at this popular Key West attraction.
Activities

Florida: Key West Overseas Highway App-Based Driving Audio Tour
