Cheap flights from Panama

View AU$268 flight on Thu, 29 Jan 2026Opens in a new window

Popular airlines from Panama

  • Avianca

    Avianca

  • United

    United

  • American Airlines

    American Airlines

  • Copa

    Copa

  • Delta

    Delta

  • Aeromexico

    Aeromexico

  • KLM

    KLM

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • trophy illustration

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheapest flights from Panama

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Sun, 22 Feb - Wed, 25 Feb
PTY
Panama City
MIA
Miami
AU$428 Return, found 4 days ago
AU$428
Return
found 4 days ago
Select Copa flight, departing Sun, 22 Feb from Panama City to Miami, returning Wed, 25 Feb, priced at AU$428 found 4 days ago
Copa
Sun, 22 Feb - Wed, 25 Feb
PTY
Panama City
MIA
Miami
AU$444 Return, found 4 days ago
AU$444
Return
found 4 days ago
Select Copa flight, departing Sun, 22 Feb from Panama City to Miami, returning Wed, 25 Feb, priced at AU$444 found 4 days ago
American Airlines
Fri, 30 Jan - Sun, 8 Feb
PTY
Panama City
MIA
Miami
AU$454 Return, found 2 days ago
AU$454
Return
found 2 days ago
Select American Airlines flight, departing Fri, 30 Jan from Panama City to Miami, returning Sun, 8 Feb, priced at AU$454 found 2 days ago
Copa
Sun, 22 Feb - Wed, 25 Feb
PTY
Panama City
MIA
Miami
AU$460 Return, found 4 days ago
AU$460
Return
found 4 days ago
Select Copa flight, departing Sun, 22 Feb from Panama City to Miami, returning Wed, 25 Feb, priced at AU$460 found 4 days ago
Aeromexico
Sun, 1 Feb - Sun, 8 Feb
PTY
Panama City
CUN
Cancun
AU$499 Return, found 2 days ago
AU$499
Return
found 2 days ago
Select Aeromexico flight, departing Sun, 1 Feb from Panama City to Cancun, returning Sun, 8 Feb, priced at AU$499 found 2 days ago
Copa
Thu, 29 Jan - Thu, 5 Feb
PTY
Panama City
MDE
Medellin
AU$508 Return, found 5 days ago
AU$508
Return
found 5 days ago
Select Copa flight, departing Thu, 29 Jan from Panama City to Medellin, returning Thu, 5 Feb, priced at AU$508 found 5 days ago
Copa
Fri, 23 Jan - Sat, 7 Feb
PTY
Panama City
BOG
Bogotá
AU$508 Return, found 4 days ago
AU$508
Return
found 4 days ago
Select Copa flight, departing Fri, 23 Jan from Panama City to Bogotá, returning Sat, 7 Feb, priced at AU$508 found 4 days ago
Copa
Fri, 16 Jan - Wed, 4 Feb
PTY
Panama City
BOG
Bogotá
AU$509 Return, found 2 days ago
AU$509
Return
found 2 days ago
Select Copa flight, departing Fri, 16 Jan from Panama City to Bogotá, returning Wed, 4 Feb, priced at AU$509 found 2 days ago
avianca
Fri, 23 Jan - Sat, 7 Feb
PTY
Panama City
BOG
Bogotá
AU$591 Return, found 4 days ago
AU$591
Return
found 4 days ago
Select avianca flight, departing Fri, 23 Jan from Panama City to Bogotá, returning Sat, 7 Feb, priced at AU$591 found 4 days ago
United
Sun, 22 Feb - Wed, 25 Feb
PTY
Panama City
MIA
Miami
AU$735 Return, found 4 days ago
AU$735
Return
found 4 days ago
Select United flight, departing Sun, 22 Feb from Panama City to Miami, returning Wed, 25 Feb, priced at AU$735 found 4 days ago
*Available to Expedia members.