Antofagasta Region Holidays

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Your Antofagasta Region Holiday

Answer the call of adventure with a tailor-made holiday package to Antofagasta Region. Wherever your travels take you and whatever you plan to do, prepare to experience a destination that'll make you truly feel alive. The easiest way to organise your trip to Antofagasta Region is to begin with its most popular cities, which include San Pedro de Atacama, Antofagasta and Historical District. Expedia has flights, hotels, car rentals and more to help you organise your very own customised Antofagasta Region holiday today.

Top destinations in Antofagasta Region

San Pedro de Atacama as well as a small group of people
FlightsFlightsHotelsHotels

San Pedro de Atacama

San Pedro de Atacama
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.
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Antofagasta Region Essential Information

Language
Spanish
Currency
Chilean pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Calama Airport (CJC)
Population
309,800
Top Sights
Valley of the Moon, Piedra del Coyote Overlook and Arco Iris Valley

Our pick of the best Antofagasta Region Hotel Deals

Diego de Almagro San Pedro de Atacama
Diego de Almagro San Pedro de Atacama
3 out of 5
Toconao 460, San Pedro de Atacama, Antofagasta
Fully refundableReserve now, pay when you stay
The price is AU$200 per night from 25 Nov to 26 Nov
AU$200
includes taxes & fees
25 Nov - 26 Nov
8/10 Very Good! (236 reviews)
"Can’t make my mind up about this hotel. There is a great pool - definitely nice to enjoy after early starts on various tours. Staff were super friendly and helpful too. However facilities in the room were quite basic. Having a fridge was a bonus however there was no safe in the room which is pretty ..."

Reviewed on 31 Oct. 2024

Diego de Almagro San Pedro de Atacama
Hotel La Casa de Don Tomas
Hotel La Casa de Don Tomas
3 out of 5
Calle Tocopilla Sitio 18, San Pedro de Atacama
Fully refundableReserve now, pay when you stay
The price is AU$291 per night from 8 Dec to 9 Dec
AU$291
includes taxes & fees
8 Dec - 9 Dec
9/10 Wonderful! (259 reviews)
"We greatly appreciated the whole ambience - clean modern room with adjoining outdoor areas for relaxing, safe parking, inclusive 24 hour hot drinks (inc. good coffee) , breakfast spread, good quality restaurant, and attentive, helpful staff. All within easy walking to the centre of town. Not the ..."

Reviewed on 14 Nov. 2024

Hotel La Casa de Don Tomas
Our Habitas Atacama
Our Habitas Atacama
4 out of 5
Domingo Atienza 282, San Pedro de Atacama, Antofagasta
The price is AU$288 per night from 1 Dec to 2 Dec
AU$288
includes taxes & fees
1 Dec - 2 Dec
8.6/10 Excellent! (250 reviews)
"Hotel muito confortável, comida refinada (vale a pena a meia-pensão), funcionários atenciosos e ambientes muito agradáveis. Tivemos uma observação e palestra noturna gratuita sobre astros muito interessante no hotel."

Reviewed on 19 Sep. 2024

Our Habitas Atacama
See all 271 properties in Antofagasta Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Beach Holidays

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Frequently asked questions

How much does an Antofagasta Region holiday package cost?
From as low as . Yes, you read that right. Our Antofagasta Region packages are the best way to stretch your budget. Combine your hotels, flights and car rentals and discover this lively destination.
How do I get a cheap travel package to Antofagasta Region?
Our Antofagasta Region holiday packages promise plenty of savings for the savvy traveller. For the best deals, simply bundle your hotel, flights and activities into an affordable package. But impressive bargains are only the start of your next unforgettable adventure. Book with Expedia and you’ll have more than 550 airlines and 1 000 000 properties throughout the world to pick from. Whatever your budget, there’s a package that’s perfect for you.
What are the top hotels in Antofagasta Region?
Have a look at ibis Antofagasta and NH Antofagasta. They’re the first choice for lots of travellers to Antofagasta. If San Pedro de Atacama is on your travel itinerary, Park Hotel Calama and Noi Casa Atacama are cosy options.
How far in advance should I book my Antofagasta Region holiday?
It can be tricky to know when is the ideal time to book your trip to Antofagasta Region. But typically the earlier you book, the better the prices. Sometimes, you can reserve your flights and hotels up to a year before your departure date. If you’re considering a last-minute getaway, no need to stress! There are fabulous deals featured on Expedia every single day.
What does an Expedia Antofagasta Region travel package include?
From hotels and airfares to rental cars, Expedia can help you shape an Antofagasta Region package that’s perfect for you. Holidaying for a week or two? Consider a rental car, hotel and flight bundle. If you’re taking a short break, a flight and hotel deal could be more your style. Activities can also be added once you’ve made your booking. Our holiday packages make it simple to save and plan.
What should I know before booking an Antofagasta Region travel package?
Tailor deals to suit your budget with an Expedia package. Airfares, hotels, rental cars — we’re a one-stop shop for all of them. You’ll save precious dollars just for bundling your bookings. Whether you’re embarking on a skiing adventure or drinking cocktails on a beach, your perfect getaway is just clicks away.
Can I choose my airline with an Antofagasta Region Expedia holiday package?
Expedia has access to more than 550 airline partners worldwide, so you sure can! Simply select your preferred carrier and put together the perfect Antofagasta Region trip.
If I'm not able to travel, can I cancel my Antofagasta Region holiday package?
Whether it’s your flight or hotel, you can cancel and rebook it. Locked in your Antofagasta Region holiday package in the last 24 hours? You may be able to make changes at no cost. For bookings older than that, you may be charged a fee by your hotel, airline or car rental company. For further information, visit our Customer Service Portal. We’ll help you every step of the way.

Discover the most popular places to visit in Antofagasta Region

Cerro Paranal Observatory

You can find out about the history of Antofagasta with a trip to Cerro Paranal Observatory. Amble around the area's seaside or visit its shops.

Cerro Paranal Observatory

What to do in Antofagasta Region

Altiplanic Lagoons

4 Tours to Discover Atacama (3 days)

AU$385
Per adult
4 Tours to Discover Atacama (3 days)
San Pedro de Atacama: 3-Day Activity Combo with 4 Tours

San Pedro de Atacama: 3-Day Activity Combo with 4 Tours

AU$330
Per adult
San Pedro de Atacama: 3-Day Activity Combo with 4 Tours
Astronomical Tour in San Pedro de Atacama

Private San Pedro de Atacama Astronomical Tour

AU$614
Per adult
Private San Pedro de Atacama Astronomical Tour
See all activities in Antofagasta Region
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.