Calle 50 Tours and Activities

Photo by Fabiola Tile
Photo by Fabiola Tile
Photo by Fabiola Tile
Photo by Fabiola Tile
Photo by Journey Of A Nomadic Family
Photo by Journey Of A Nomadic Family
Photo by Simon Gerald
Photo by Simon Gerald
Photo by Stefan Messing
Photo by Stefan Messing

Tours & day trips

See all 372 activities
Full Day Fishing at South Pearl Islands on Private Yacht

Full Day Fishing at South Pearl Islands on Private Yacht

Activity duration is 10 hours
Free cancellation available
Price is AU$6,978 per traveller*
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History & culture

See all 182 activities
Stopover in Panama 6 days Nature in Panama

Stopover in Panama 6 days Nature in Panama

Activity duration is 6 days
Free cancellation available
Price is AU$2,186 per adult*
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Adventure & outdoor

See all 95 activities
Full Day Fishing at South Pearl Islands on Private Yacht

Full Day Fishing at South Pearl Islands on Private Yacht

Activity duration is 10 hours
Free cancellation available
Price is AU$6,978 per traveller*
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Food, drink & nightlife

See all 32 activities
Full Day Private Taboga Boat Tour with Fishing and Barbeque

Full Day Private Taboga Boat Tour with Fishing and Barbeque

Activity duration is 8 hours
Free cancellation available
Price is AU$709 per adult*
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Classes & workshops

See all 11 activities
10-Recipe Boozy Panamanian Eat-as-you-Cook Class

10-Recipe Boozy Panamanian Eat-as-you-Cook Class

Activity duration is 4 hours
10.0 out of 10 with 2 reviews
Free cancellation available
Price is AU$151 per adult*
10-Recipe Boozy Panamanian Eat-as-you-Cook ClassOpens in new tab

Popular places to visit

Soho City Center

Soho City Center

You can enjoy retail therapy at Soho City Center during your trip to Panama City. Discover the area's shops or seek out its local tours.

Soho City Center
Multiplaza Pacific Mall

Multiplaza Pacific Mall

You can find the perfect gifts to bring home when you visit Multiplaza Pacific Mall, a popular shopping spot in Panama City. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Avenida Balboa

Avenida Balboa

You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa
Uruguay Street

Uruguay Street

During your visit to Panama City, you can search for that perfect souvenir at Uruguay Street. While in this family-friendly area, you can savour the top-notch restaurants.

Uruguay Street

Bingo 90

Why not roll the dice with a visit to Bingo 90 during your travels in Panama City? Visit the shops and casinos in this vibrant area.

Bingo 90

National Shrine of the Heart of Mary

You can learn about the history of Panama City with a trip to National Shrine of the Heart of Mary. Stroll along the seaside or visit the shops in this vibrant area.

National Shrine of the Heart of Mary

Top Calle 50 Hotel & Accommodation Deals

Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Hotel Riu Plaza Panama
Decapolis Hotel Panama City
Decapolis Hotel Panama City
4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
Decapolis Hotel Panama City
Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
Plaza Paitilla Inn Hotel
W Panama
W Panama
5 out of 5
Calle Aquilino de la Guardia & Calle 50, Bella Vista, Panama City
W Panama
Principe Hotel and Suites
Principe Hotel and Suites
3 out of 5
Via Argentina, Panama City, Panama
Principe Hotel and Suites
Hospedium Princess Hotel Panama
Hospedium Princess Hotel Panama
3.5 out of 5
Calle 53 Marbella y Avenida 5a B sur, World Trade Center building, Panama City, Panama
Hospedium Princess Hotel Panama
Ramada Plaza By Wyndham Panama Punta Pacífica
Ramada Plaza By Wyndham Panama Punta Pacífica
4 out of 5
Via Israel y Calle 71, San Francisco, Panama City, Panama
Ramada Plaza By Wyndham Panama Punta Pacífica
Novotel Panama City
Novotel Panama City
4 out of 5
Calle Jose I. Fabrega y Thais de Pons, El Cangre, Bella Vista, Panama City, Panama
Novotel Panama City
Megapolis Hotel Panamá
Megapolis Hotel Panamá
4.5 out of 5
Avenida Balboa, Panama City
Megapolis Hotel Panamá
See all 1,364 properties in Calle 50
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.