East Seneca Hotels, Buffalo

Start date: Check-in selected.
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
8 Sept - 9 Sept
Tomorrow
9 Sept - 10 Sept
This weekend
12 Sept - 14 Sept
Next weekend
19 Sept - 21 Sept

Filter by

Guest rating
Guest rating
Star rating

764 Cheap Hotels in East Seneca - Specials, Reviews, & Last Minute Deals

Our top choices for East Seneca hotels

Buffalo Guesthouse
Exterior

Buffalo Guesthouse

3.0 star property
9.2 out of 10, Wonderful, (65)
"Great place to stay"
The price is AU$264
includes taxes & fees
12 Sept - 13 Sept
Buffalo Guesthouse
Quality Inn Near Walden Galleria Mall
Free daily continental breakfast

Quality Inn Near Walden Galleria Mall

2.5 star property
8.0 out of 10, Very good, (1007)
"This was the best trip ever"
The price is AU$177
includes taxes & fees
15 Sept - 16 Sept
Quality Inn Near Walden Galleria Mall
La Quinta Inn by Wyndham Buffalo Airport
Exterior

La Quinta Inn by Wyndham Buffalo Airport

3.0 star property
7.8 out of 10, Good, (1243)
"Very nice place"
The price is AU$145
includes taxes & fees
29 Sept - 30 Sept
La Quinta Inn by Wyndham Buffalo Airport
La Quinta Inn & Suites by Wyndham Buffalo Amherst
Lobby

La Quinta Inn & Suites by Wyndham Buffalo Amherst

3.0 star property
8.4 out of 10, Very good, (1919)
"Nice place to stay "
The price is AU$179
includes taxes & fees
14 Sept - 15 Sept
La Quinta Inn & Suites by Wyndham Buffalo Amherst
M Hotel Buffalo
Reception hall

M Hotel Buffalo

3.5 star property
7.4 out of 10, Good, (2101)
"Very nice stay- breakfast was amazing "
The price is AU$171
includes taxes & fees
16 Sept - 17 Sept
M Hotel Buffalo
Tru by Hilton Williamsville Buffalo Airport
BBQ/picnic area

Tru by Hilton Williamsville Buffalo Airport

2.5 star property
8.8 out of 10, Excellent, (1005)
"Great location, clean, super friendly staff. "
The price is AU$204
includes taxes & fees
7 Oct - 8 Oct
Tru by Hilton Williamsville Buffalo Airport
Best Western Buffalo Inn & Suites
Lobby

Best Western Buffalo Inn & Suites

2.5 star property
8.8 out of 10, Excellent, (752)
"Great place to stay"
The price is AU$165
includes taxes & fees
16 Sept - 17 Sept
Best Western Buffalo Inn & Suites
Econo Lodge South
Exterior

Econo Lodge South

2.0 star property
7.4 out of 10, Good, (568)
"The room was very spacious and clean. "
The price is AU$123
includes taxes & fees
8 Oct - 9 Oct
Econo Lodge South
Sleep Inn & Suites Buffalo Airport
Lobby

Sleep Inn & Suites Buffalo Airport

2.5 star property
7.8 out of 10, Good, (1716)
"Great property, friendly, clean and comfortable "
The price is AU$119
includes taxes & fees
7 Oct - 8 Oct
Sleep Inn & Suites Buffalo Airport
Hampton Inn Buffalo - Amherst, NY
Exterior

Hampton Inn Buffalo - Amherst, NY

2.5 star property
9.4 out of 10, Exceptional, (1828)
"Friendly, clean, ample breakfast selection, pool was clean and well kept with lots of seating around pool area."
The price is AU$197
includes taxes & fees
21 Sept - 22 Sept
Hampton Inn Buffalo - Amherst, NY
Buffalo Airport Hotel
Courtyard view

Buffalo Airport Hotel

3.0 star property
8.0 out of 10, Very good, (2645)
"Good stay"
The price is AU$166
includes taxes & fees
10 Sept - 11 Sept
Buffalo Airport Hotel
Holiday Inn Express Buffalo NE Lockport by IHG
Exterior

Holiday Inn Express Buffalo NE Lockport by IHG

2.5 star property
9.2 out of 10, Wonderful, (686)
"Really nice "
The price is AU$210
includes taxes & fees
1 Oct - 2 Oct
Holiday Inn Express Buffalo NE Lockport by IHG
CenterWay Hotel Tonawanda
Exterior

CenterWay Hotel Tonawanda

2.0 star property
7.8 out of 10, Good, (1002)
"Very convenient to the places we needed to be during our visit and the staff were very nice. "
The price is AU$131
includes taxes & fees
15 Sept - 16 Sept
CenterWay Hotel Tonawanda
Extended Stay America Suites - Buffalo - Airport
Lobby

Extended Stay America Suites - Buffalo - Airport

2.5 star property
7.2 out of 10, Good, (899)
"Good stay"
The price is AU$128
includes taxes & fees
21 Sept - 22 Sept
Extended Stay America Suites - Buffalo - Airport
Clarence Inn
Front of property

Clarence Inn

2.0 star property
8.0 out of 10, Very good, (271)
"I'd stay here again for that price, really had a good stay"
The price is AU$151
includes taxes & fees
22 Sept - 23 Sept
Clarence Inn
Comfort Inn University
Lobby

Comfort Inn University

2.5 star property
8.0 out of 10, Very good, (1081)
"Great choice for a quick stay. "
The price is AU$185
includes taxes & fees
8 Oct - 9 Oct
Comfort Inn University
Holiday Inn Express Cheektowaga North East by IHG
Exterior

Holiday Inn Express Cheektowaga North East by IHG

2.5 star property
8.4 out of 10, Very good, (1123)
"Good property to stay at in Buffalo "
The price is AU$228
includes taxes & fees
7 Oct - 8 Oct
Holiday Inn Express Cheektowaga North East by IHG
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
Property entrance

Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

2.5 star property
8.2 out of 10, Very good, (1003)
"Very nice hotel near the airport"
The price is AU$194
includes taxes & fees
15 Sept - 16 Sept
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
Red Roof Inn Buffalo - Niagara Airport
Lobby lounge

Red Roof Inn Buffalo - Niagara Airport

2.0 star property
7.4 out of 10, Good, (1001)
"It is close to the busy noisy high way The room was a good size Small bathroom and old toilet and tub "
The price is AU$148
includes taxes & fees
21 Sept - 22 Sept
Red Roof Inn Buffalo - Niagara Airport
Springhill Suites Buffalo Airport
Front of property - evening/night

Springhill Suites Buffalo Airport

2.5 star property
9.0 out of 10, Wonderful, (786)
"Nice hotel "
The price is AU$216
includes taxes & fees
2 Oct - 3 Oct
Springhill Suites Buffalo Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Our guide on where to stay in East Seneca

Find the best East Seneca areas for the activities you enjoy most.
Buffalo showing a city, a high-rise building and a monument

Downtown Buffalo

1 out of top 10 points of interest in this area

Known for its great bars and great live music, there's plenty to explore in Downtown Buffalo. You can visit top attractions like Chippewa District and Statler Tower, and jump on the metro at Fountain Plaza Station or Lafayette Square Station to see more of the city.

Lakeview

If you're looking for some top things to see and do in Lakeview and surrounding area, you can visit Kleinhans Music Hall and Chippewa District.

Delaware Park showing a lake or waterhole

North Buffalo

1 out of top 10 points of interest in this area

North Buffalo is well liked for its live music and zoo. If you're hoping to get in some sightseeing, Buffalo Zoo and Buffalo AKG Art Museum are top spots, and you can jump on the metro at Amherst Street Station or Lasalle Station to get around.

Elmwood Village

Elmwood Village is known for its live music, and you can plan a trip to Blue Sky Mausoleum and Ujima Theatre Company while you're in town.

Allentown

Allentown is noteworthy for its restaurants, and you can make a stop at top attractions like Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site and Theater of Youth.

Top East Seneca Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What is East Seneca like?

Travellers will be sure to enjoy their time in West Seneca's East Seneca neighbourhood.

If I need to cancel my hotel reservation in East Seneca, will I receive a refund?

Yes! Most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to view the best deals in East Seneca.

What is there to do in this West Seneca neighbourhood?

A few places to visit in the area around East Seneca include Southgate Plaza, Harvest Hill Golf Course and Charles E. Burchfield Nature and Art Center. You might also plan a visit to Enjoy The Journey Art Gallery when you're sightseeing in West Seneca.