Otay Mesa Hotels, San Diego

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Our top choices for Otay Mesa hotels

Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.0 out of 10, Good, (1,000 reviews)
"Great staff.. location close to the airport!"
United States
Vivian
The price is AU$158
includes taxes & fees
27 Feb - 28 Feb
Quality Suites San Diego Otay Mesa

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.0 out of 10, Very good, (1,652 reviews)
"Clean, great breakfast, good service."
United States
Sara
The price is AU$206
includes taxes & fees
8 Mar - 9 Mar
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Berkshire Motor Hotel

Berkshire Motor Hotel
2.5 star property
North Park, 26.7 km from Otay Mesa
8.4 out of 10, Very good, (1,002 reviews)
"Clean, very chill easy check in"
United States
Susana
The price is AU$142
includes taxes & fees
1 Mar - 2 Mar
Berkshire Motor Hotel

Courtyard by Marriott Old Town

Courtyard by Marriott Old Town
3.0 star property
Old Town San Diego, 29.7 km from Otay Mesa
8.6 out of 10, Excellent, (1,000 reviews)
"Great place!!!"
United States
Hannah
The price is AU$273
includes taxes & fees
8 Mar - 9 Mar
Courtyard by Marriott Old Town

Westgate Hotel

Westgate Hotel
4.5 star property
24.9 km from Otay Mesa
9.0 out of 10, Wonderful, (1,002 reviews)
"Great stay"
United States
ESMERALDA
Westgate Hotel

Ocean Villa Inn

Ocean Villa Inn
2.5 star property
Ocean Beach, 33.7 km from Otay Mesa
8.0 out of 10, Very good, (1,180 reviews)
"Beds are super comfy clean and renovated"
United States
Esmeralda
Ocean Villa Inn

Sea Harbor Hotel

Sea Harbor Hotel
2.0 star property
30.1 km from Otay Mesa
8.6 out of 10, Excellent, (1,001 reviews)
"Super clean rooms and a great location "
United States
Mark
Sea Harbor Hotel

Super 8 by Wyndham San Diego Hotel Circle

Super 8 by Wyndham San Diego Hotel Circle
2.0 star property
28.8 km from Otay Mesa
7.2 out of 10, Good, (709 reviews)
"Staff was great, the room was very clean."
Canada
Jennifer
The price is AU$126
includes taxes & fees
1 Mar - 2 Mar
Super 8 by Wyndham San Diego Hotel Circle

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 24.2 km from Otay Mesa
9.4 out of 10, Exceptional, (1,001 reviews)
"Great location and stay. "
United States
Simran
The price is AU$260
includes taxes & fees
2 Mar - 3 Mar
Staypineapple, Hotel Z, Gaslamp San Diego

Fairfield Inn & Suites San Diego Old Town

Fairfield Inn & Suites San Diego Old Town
3.0 star property
Old Town San Diego, 29.4 km from Otay Mesa
8.8 out of 10, Excellent, (1,006 reviews)
"Great location, clean rooms, good breakfast"
United States
Jingyi
The price is AU$218
includes taxes & fees
15 Mar - 16 Mar
Fairfield Inn & Suites San Diego Old Town

Old Town Western Inn & Suites

Old Town Western Inn & Suites
2.5 star property
Old Town San Diego, 29.6 km from Otay Mesa
7.6 out of 10, Good, (1,004 reviews)
"Clean, good staff, quiet, good location "
United States
Raul
Old Town Western Inn & Suites

Heritage Inn San Diego

Heritage Inn San Diego
2.0 star property
31.8 km from Otay Mesa
7.4 out of 10, Good, (1,281 reviews)
"Clean room, staff was great during check in and checking out. "
United States
Amber
The price is AU$100
includes taxes & fees
24 Mar - 25 Mar
Heritage Inn San Diego

Ash&9th

Ash&9th
2.0 star property
24.7 km from Otay Mesa
8.4 out of 10, Very good, (370 reviews)
"Great location… stuff was really friendly "
United States
Aurora
The price is AU$125
includes taxes & fees
12 Mar - 13 Mar
Ash&9th

Best Western Plus Bayside Inn

Best Western Plus Bayside Inn
3.0 star property
25.4 km from Otay Mesa
9.0 out of 10, Wonderful, (1,000 reviews)
"Clean rooms, friendly staff, hotel close to eateries "
United States
Debbie
The price is AU$233
includes taxes & fees
29 Mar - 30 Mar
Best Western Plus Bayside Inn

Porto Vista Hotel Downtown

Porto Vista Hotel Downtown
3.5 star property
Little Italy, 25.8 km from Otay Mesa
7.0 out of 10, Good, (1,227 reviews)
"Great location, friendly staff, dog friendly and nice rooms! "
United States
Chelsea
Porto Vista Hotel Downtown

The Inn at Sunset Cliffs

The Inn at Sunset Cliffs
2.5 star property
Ocean Beach, 32.9 km from Otay Mesa
9.2 out of 10, Wonderful, (1,001 reviews)
"Great location, staff was so friendly and courteous, and amazing views!"
United States
Katrina
The price is AU$341
includes taxes & fees
8 Mar - 9 Mar
The Inn at Sunset Cliffs

Ocean Beach Hotel

Ocean Beach Hotel
3.0 star property
Ocean Beach, 33.5 km from Otay Mesa
8.8 out of 10, Excellent, (1,273 reviews)
"The hotel was a great environment and felt very safe and comfortable. "
United States
Charity
Ocean Beach Hotel

Comfort Inn San Diego Airport At The Harbor

Comfort Inn San Diego Airport At The Harbor
3.5 star property
30.1 km from Otay Mesa
7.8 out of 10, Good, (1,322 reviews)
"Spotless! Very kind and attentive staff at checkin! Very impressed and will be back! "
United States
Michelle
The price is AU$174
includes taxes & fees
10 Mar - 11 Mar
Comfort Inn San Diego Airport At The Harbor

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
Gaslamp Quarter, 24.6 km from Otay Mesa
9.0 out of 10, Wonderful, (1,024 reviews)
"Clean quiet friendly helpful staff convenient location will stay there again"
United States
David
The price is AU$220
includes taxes & fees
8 Mar - 9 Mar
Gaslamp Plaza Suites

Urban Boutique Hotel

Urban Boutique Hotel
3.0 star property
Little Italy, 25.7 km from Otay Mesa
8.6 out of 10, Excellent, (1,268 reviews)
"Great location, clean rooms, friendly staff"
United States
Beth
Urban Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Pacific Beach

Get to Pacific Beach after the sun goes down because this is the place to be in San Diego for partying.

Gaslamp Quarter

The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.

Ocean Beach

With a secluded sunbathing beach, swimming-only beach, special surf beach, volleyball beach and dog beach, San Diego’s “OB” sure takes beaches seriously.

Top Otay Mesa Hotel Reviews

Frequently asked questions

What's it like in Otay Mesa?
Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.
Where is the best hotel for a stay in Otay Mesa?
Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.
If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?
Yes! Most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.
What is there to do in this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.

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