Otay Mesa Travel Guide

Tourist Guide


Popular places to visit

Activities


Our pick of the best Otay Mesa Hotel Deals

The Dana on Mission Bay
The Dana on Mission Bay
3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
The price is AU$303 per night from 20 Apr to 21 Apr
AU$303
includes taxes & fees
20 Apr - 21 Apr
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (3,296 reviews)
"Very clean room and hotel. Convenient restaurant on the 5th floor of the building. Walking distance to Belize water taxi"

Reviewed on 23 Mar. 2025

The Dana on Mission Bay
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is AU$272 per night from 18 Apr to 19 Apr
AU$272
includes taxes & fees
18 Apr - 19 Apr
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,649 reviews)
"Lili at front desk amazing please give an raise....and the lovely lady who checked us in.... wonderful....all staff and room .... incredible ❤️❤️❤️"

Reviewed on 24 Mar. 2025

Wyndham San Diego Bayside
San Diego Mission Bay Resort
San Diego Mission Bay Resort
4 out of 5
1775 E Mission Bay Dr, San Diego, CA
The price is AU$427 per night from 21 Apr to 22 Apr
AU$427
includes taxes & fees
21 Apr - 22 Apr
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
8.2/10 Very Good! (1,149 reviews)
"Great relaxing place to spend a weekend."

Reviewed on 24 Mar. 2025

San Diego Mission Bay Resort
Best Western Seven Seas
Best Western Seven Seas
3 out of 5
411 Hotel Circle South, San Diego, CA
The price is AU$163 per night from 27 Mar to 28 Mar
AU$163
includes taxes & fees
27 Mar - 28 Mar
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
7.6/10 Good! (2,642 reviews)
5 STARS
"Staff were super amazing. I actually had to leave another room due to the conditions and best western accommodated me to the best of their ability. The room was clean and close to everything. Will definitely be booking again every time I visit San Diego."

Reviewed on 25 Mar. 2025

Best Western Seven Seas
Comfort Inn Sea World Area
Comfort Inn Sea World Area
3.5 out of 5
3880 Greenwood St, San Diego, CA
The price is AU$201 per night from 21 Apr to 22 Apr
AU$201
includes taxes & fees
21 Apr - 22 Apr
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,820 reviews)
"Great location, close to lots of shopping, sea world, and old town. Very clean. Breakfast is hot and delicious."

Reviewed on 25 Mar. 2025

Comfort Inn Sea World Area
Legacy Resort Hotel & Spa
Legacy Resort Hotel & Spa
4 out of 5
875 Hotel Circle South, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is AU$356 per night from 30 Mar to 31 Mar
AU$356
includes taxes & fees
30 Mar - 31 Mar
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
9/10 Wonderful! (2,859 reviews)
"I picked this place because it was central but also pretty new. It is well taken care of and the lobby is gorgeous."

Reviewed on 23 Mar. 2025

Legacy Resort Hotel & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Otay Mesa

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Mid-City

While you're in Mid-City, take in top sights like Cal Coast Credit Union Open Air Theater or Viejas Arena, and hop on the metro to see more of the city at SDSU Transit Center Station or Alvarado Station.

Mid-City
Gaslamp Quarter featuring a bar, night scenes and street scenes

Gaslamp Quarter

Cosy bars interesting history and top sights from Lyceum Theatre to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

Gaslamp Quarter
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Downtown San Diego

4.5/5(100 area reviews)

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Downtown San Diego
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North Park

North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.

North Park
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Little Italy

Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.

Little Italy
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Del Cerro

While there might not be top attractions in Del Cerro, you can explore the larger area and discover places like Cal Coast Credit Union Open Air Theater and Viejas Arena.

Del Cerro

Otay Mesa Travel Guide

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