Otay Mesa Travel Guide

Tourist Guide

Popular places to visit

San Diego Zoo which includes a pond, zoo animals and landscape views

San Diego Zoo

4.5/5(26 reviews)

One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.

San Diego Zoo
San Diego Convention Center

San Diego Convention Center

4.5/5(13 reviews)

During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's acclaimed art galleries and entertainment choices.

San Diego Convention Center
Mission Bay showing a beach

Mission Bay

4/5(10 reviews)

Mission Bay is San Diego’s vast and beautiful outdoor playground with great weather and calm waters that seem made for watersports.

Mission Bay
SeaWorld

SeaWorld

4/5(12 reviews)

A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.

SeaWorld
Balboa Park

Balboa Park

4.5/5(20 reviews)

One of America’s largest urban green spaces, Balboa Park is an exciting spot packed with art, culture, and a world-renowned zoo.

Balboa Park
Port of San Diego

Port of San Diego

4.5/5(19 reviews)

Explore the waterfront in San Diego with a trip to Port of San Diego. Wander the seaside and beautiful beaches in the area.

Port of San Diego

Activities

Crossing Borders: Tijuana Day Trip from San Diego

Crossing Borders: Tijuana Day Trip from San Diego

AU$150
per adult
100% of travellers recommend
Crossing Borders: Tijuana Day Trip from San Diego
Las Americas outlet entrance

San Diego Shopping Tour to Las Amercias Outlet

AU$67
per adult
San Diego Shopping Tour to Las Amercias Outlet
Tour from San Diego to Rosarito / Portales / Puerto Nuevo Lobster

Tour from San Diego to Rosarito / Portales / Puerto Nuevo Lobster

AU$159
per adult
Tour from San Diego to Rosarito / Portales / Puerto Nuevo Lobster
San Diego USS Midway with Waterfront Walking Tour

San Diego USS Midway with Waterfront Walking Tour

AU$105
per adult
San Diego USS Midway with Waterfront Walking Tour
From Tijuana: Valle de Guadalupe Shared Winery Tour

From Tijuana: Valle de Guadalupe Shared Winery Tour

AU$115
per adult
From Tijuana: Valle de Guadalupe Shared Winery Tour
Kayak on the San Diego Bay

Kayak on the San Diego Bay

AU$32
per adult
Kayak on the San Diego Bay
See all activities in San Diego

Our pick of the best Otay Mesa Hotel Deals

Paradise Point Resort & Spa
Paradise Point Resort & Spa
4 out of 5
1404 Vacation Rd, San Diego, CA
The price is AU$382 per night from 5 Jan to 6 Jan
AU$382
includes taxes & fees
5 Jan - 6 Jan 2025
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.4/10 Very Good! (1,972 reviews)
"Always enjoy how peaceful this place is"

Reviewed on 23 Dec. 2024

Paradise Point Resort & Spa
Manchester Grand Hyatt San Diego
Manchester Grand Hyatt San Diego
4 out of 5
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is AU$399 per night from 29 Dec to 30 Dec
AU$399
includes taxes & fees
29 Dec - 30 Dec
Book a stay at this eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
8.8/10 Excellent! (2,818 reviews)
Fabulous view of the harbor
"We recently stayed at the Manchester Grand Hyatt and had an incredible experience. Our corner room offered breathtaking views that made our stay feel truly special. The expansive windows showcased stunning city and waterfront panoramas, creating a perfect backdrop for relaxation. The staff at the ..."

Reviewed on 24 Dec. 2024

Manchester Grand Hyatt San Diego
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is AU$275 per night from 6 Jan to 7 Jan
AU$275
includes taxes & fees
6 Jan - 7 Jan 2025
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,521 reviews)
"Great location and clean! Would absolutely stay here again."

Reviewed on 24 Dec. 2024

Wyndham San Diego Bayside
The Dana on Mission Bay
The Dana on Mission Bay
3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
The price is AU$269 per night from 5 Jan to 6 Jan
AU$269
includes taxes & fees
5 Jan - 6 Jan 2025
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 spa tubs. Our guests praise the pool and the restaurant in ...
8.6/10 Excellent! (2,962 reviews)
"They really thought if everything answered the phone right sway housekeeping came and hit the spider in the wall right away plenty of plush towels and nice shampoos and body wash fluffy pillows clean sheets my temperature setting was perfect when we arrived my husband and I has beach view ..."

Reviewed on 24 Dec. 2024

The Dana on Mission Bay
Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld
3 out of 5
3737 Sports Arena Blvd, San Diego, CA
The price is AU$170 per night from 6 Jan to 7 Jan
AU$170
includes taxes & fees
6 Jan - 7 Jan 2025
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, parking (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
7.2/10 Good! (3,652 reviews)
"It was good for our 1 night stay"

Reviewed on 22 Dec. 2024

Wyndham Garden San Diego Near SeaWorld
Comfort Inn Sea World Area
Comfort Inn Sea World Area
3.5 out of 5
3880 Greenwood St, San Diego, CA
The price is AU$170 per night from 6 Jan to 7 Jan
AU$170
includes taxes & fees
6 Jan - 7 Jan 2025
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,296 reviews)
"The advertisement of this property was false. Nothing like the pictures. Dirty floors, shower no pressure, bad area lots of homeless, nasty smell in the rooms. Not very happy with this place."

Reviewed on 23 Dec. 2024

Comfort Inn Sea World Area
See all 4,483 properties in Otay Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Otay Mesa

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Mid-City

While you're in Mid-City, take in top sights like Viejas Arena or San Diego State University Art Gallery, and hop on the metro to see more of the city at SDSU Transit Center Station or Alvarado Station.

Mid-City
Gaslamp Quarter featuring a bar, night scenes and street scenes

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

Gaslamp Quarter
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Downtown San Diego

4.5/5(100 area reviews)

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Balboa Park and San Diego Civic Theatre are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Downtown San Diego
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North Park

North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and Balboa Park if you have time to explore the area.

North Park
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Little Italy

Visitors to Little Italy love its captivating waterfront views, and you can check out Waterfront Park and Maritime Museum of San Diego. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.

Little Italy
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Hillcrest

Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.

Hillcrest

Otay Mesa Travel Guide

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