Otay Mesa Travel Guide
Tourist Guide
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's fascinating museums and entertainment choices.
Mission Bay
Mission Bay is San Diego’s vast and beautiful outdoor playground with great weather and calm waters that seem made for watersports.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Balboa Park
One of America’s largest urban green spaces, Balboa Park is an exciting spot packed with art, culture, and a world-renowned zoo.
Mission Beach
A seaside village and a popular spot for holiday-makers for over a century, which today still retains its antique charm.
Activities
Crossing Borders: Tijuana Day Trip from San Diego
San Diego USS Midway with Waterfront Walking Tour
Tour from San Diego to Rosarito / Portales / Puerto Nuevo Lobster
Crossing Borders: Tijuana Day Trip from San Diego
From Tijuana: Valle de Guadalupe Private Winery Tour
Our pick of the best Otay Mesa Hotel Deals
Reviewed on 15 Feb. 2025
Reviewed on 14 Feb. 2025
Reviewed on 15 Feb. 2025
Reviewed on 13 Feb. 2025
Reviewed on 17 Feb. 2025
Reviewed on 15 Feb. 2025
Other neighbourhoods around Otay Mesa
Mid-City
While you're in Mid-City, take in top sights like Cal Coast Credit Union Open Air Theater or Viejas Arena, and hop on the metro to see more of the city at SDSU Transit Center Station or Alvarado Station.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and USS Midway Museum are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and Balboa Park if you have time to explore the area.
Little Italy
Visitors to Little Italy love its captivating waterfront views, and you can check out Waterfront Park and Maritime Museum of San Diego. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.