Otay Mesa Travel Guide
Tourist Guide
Popular places to visit
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's fascinating museums and acclaimed art galleries.
Mission Bay
Mission Bay is San Diego’s vast and beautiful outdoor playground with great weather and calm waters that seem made for watersports.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Mission Beach
A seaside village and a popular spot for holiday-makers for over a century, which today still retains its antique charm.
SeaWorld
A fun family favourite, where you can get up close to the local marine life, enjoy fun rides and be wowed by the performances.
Activities
Tour from San Diego to Rosarito / Portales / Puerto Nuevo Lobster
Crossing Borders: Tijuana Day Trip from San Diego
Introduction Rosarito Day Tour from San Diego
Our pick of the best Otay Mesa Hotel Deals
Wyndham San Diego Bayside
Reviewed on 1 Oct 2025
Manchester Grand Hyatt San Diego
Reviewed on 29 Sept 2025
The DEXTRO Little Italy, BW Premier Collection
Reviewed on 1 Oct 2025
Handlery Hotel
Reviewed on 1 Oct 2025
The Dana on Mission Bay
Reviewed on 30 Sept 2025
Palihotel San Diego Gaslamp Quarter
Reviewed on 29 Sept 2025
Other neighbourhoods around Otay Mesa
East Village
Travellers choose East Village for its great bars. Hop aboard the metro at City College Trolley Station or Park and Market Trolley Station and check out top sights like Petco Park.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.
Little Italy
Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.
Del Cerro
While there might not be top attractions in Del Cerro, you can explore the larger area and discover places like Cal Coast Credit Union Open Air Theater and Viejas Arena.
Otay Mesa Travel Guide
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