Otay Mesa Travel Guide

Tourist Guide


Popular places to visit

Activities


Our pick of the best Otay Mesa Hotel Deals

The Dana on Mission Bay
The Dana on Mission Bay
3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
The price is AU$319 per night from 26 Mar to 27 Mar
AU$319
includes taxes & fees
26 Mar - 27 Mar
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
8.6/10 Excellent! (3,250 reviews)
"The excellent ratings are well-deserved!"

Reviewed on 12 Mar. 2025

The Dana on Mission Bay
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2.5 out of 5
2485 Hotel Circle Place, San Diego, CA
The price is AU$216 per night from 25 Mar to 26 Mar
AU$216
includes taxes & fees
25 Mar - 26 Mar
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,333 reviews)
"Didn't like the 25.00 day for parking"

Reviewed on 12 Mar. 2025

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
San Diego Mission Bay Resort
San Diego Mission Bay Resort
4 out of 5
1775 E Mission Bay Dr, San Diego, CA
The price is AU$444 per night from 18 Mar to 19 Mar
AU$444
includes taxes & fees
18 Mar - 19 Mar
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
8.2/10 Very Good! (1,115 reviews)
"Staff members were above expectations. Food was AMAZING! Room was clean and spacious. We got the room with a view and the view was so cute. Our waiter Omar was so patient and friendly we had to give him a wonderful tip! Allie and Ginger and mika were all so delightful! The food service manager was ..."

Reviewed on 6 Mar. 2025

San Diego Mission Bay Resort
Comfort Inn Sea World Area
Comfort Inn Sea World Area
3.5 out of 5
3880 Greenwood St, San Diego, CA
The price is AU$192 per night from 26 Mar to 27 Mar
AU$192
includes taxes & fees
26 Mar - 27 Mar
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,737 reviews)
"Very comfortable room, everything was clean and the beds were great as well. It’s very close to old town, sea world, San Diego zoo, and many other attractions San Diego has to offer. The area around the property isn’t the greatest, but the hotel is gated and the underground parking is secure. We ..."

Reviewed on 13 Mar. 2025

Comfort Inn Sea World Area
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is AU$287 per night from 16 Mar to 17 Mar
AU$287
includes taxes & fees
16 Mar - 17 Mar
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,591 reviews)
"Great location, customer service, and clean!"

Reviewed on 12 Mar. 2025

Wyndham San Diego Bayside
Humphreys Half Moon Inn
Humphreys Half Moon Inn
3.5 out of 5
2303 Shelter Island Dr, San Diego, CA
The price is AU$318 per night from 17 Mar to 18 Mar
AU$318
includes taxes & fees
17 Mar - 18 Mar
Book a stay at this business-friendly hotel in San Diego. Enjoy a marina, a nightclub, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
9/10 Wonderful! (2,181 reviews)
"Location"

Reviewed on 12 Mar. 2025

Humphreys Half Moon Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Otay Mesa

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Mid-City

While you're in Mid-City, take in top sights like Cal Coast Credit Union Open Air Theater or Viejas Arena, and hop on the metro to see more of the city at SDSU Transit Center Station or Alvarado Station.

Mid-City
Gaslamp Quarter featuring a bar, night scenes and street scenes

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

Gaslamp Quarter
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Downtown San Diego

4.5/5(100 area reviews)

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Downtown San Diego
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North Park

North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.

North Park
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Little Italy

Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.

Little Italy
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Del Cerro

While there might not be top attractions in Del Cerro, you can explore the larger area and discover places like Cal Coast Credit Union Open Air Theater and Viejas Arena.

Del Cerro

Otay Mesa Travel Guide

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