Search Quebrada San Isidro hotels

  • Plan, book, stay with confidence
    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check Quebrada San Isidro hotel prices

Tonight
25 Nov - 26 Nov
Tomorrow night
26 Nov - 27 Nov
This weekend
29 Nov - 1 Dec
Next weekend
6 Dec - 8 Dec

Filter by

Guest rating
Guest rating
Property class

Top hotels and accommodation in Quebrada San Isidro

Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.
Unlock Black Friday deals

Frequently asked questions

If I need to cancel my hotel reservation in Quebrada San Isidro, will I receive a refund?

Yes! The majority of hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Quebrada San Isidro.

What is there to see in Quebrada San Isidro?

Places to visit in the wider area include Darien National Park and Río Sambú. Take a look at what more there is to see and do in Expedia's Quebrada San Isidro guide.

What's the seasonal weather in Quebrada San Isidro?

The hottest months are usually February and April, with an average temperature of 26°C, while the coldest months are October and November, with an average of 26°C. The rainiest months in Quebrada San Isidro are August, May, July and October, with each month seeing an average of 354 mm of rainfall.