Medical Center District Travel Guide

Tourist Guide

Photo by Linda Cronan

Popular places to visit

Activities


Our pick of the best Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
The price is AU$160 per night from 24 July to 25 July
AU$160
24 July - 25 July
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (2,772 reviews)
"Accessible to highway."

Reviewed on 22 Jul. 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410, San Antonio, TX
The price is AU$158 per night from 5 Aug to 6 Aug
AU$158
5 Aug - 6 Aug
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Antonio. Enjoy free parking, a free area shuttle, and room service. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,019 reviews)
Clean, easy, and comfortable
"Check in was quick and efficient. Our room on the first floor was clean and spacious. We bought breakfast with our room reservation. It was fine, but the service was top notch. I'd stay here again should we be back in San Antonio"

Reviewed on 21 Jul. 2025

San Antonio Marriott Northwest Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 out of 5
7203 Wurzbach Road, San Antonio, TX
The price is AU$164 per night from 3 Aug to 4 Aug
AU$164
3 Aug - 4 Aug
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (929 reviews)
"Great no complaints!"

Reviewed on 23 Jul. 2025

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street, Dwyer/Main Plaza, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is AU$177 per night from 29 July to 30 July
AU$177
29 July - 30 July
includes taxes & fees
Stay at this 4-star family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
8/10 Very Good! (5,573 reviews)
"clean room, staff very friendly"

Reviewed on 21 Jul. 2025

Riverwalk Plaza
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

3 out of 5
105 S Saint Marys Street, San Antonio, TX
The price is AU$222 per night from 3 Aug to 4 Aug
AU$222
3 Aug - 4 Aug
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (3,551 reviews)
"Staff was great"

Reviewed on 21 Jul. 2025

Drury Plaza Hotel San Antonio Riverwalk
Crockett Hotel

Crockett Hotel

3 out of 5
320 Bonham, San Antonio, TX
The price is AU$173 per night from 5 Aug to 6 Aug
AU$173
5 Aug - 6 Aug
includes taxes & fees
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, valet parking (surcharge), and a 24-hour front desk. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (2,427 reviews)
"Will definitely be back"

Reviewed on 21 Jul. 2025

Crockett Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Los Angeles Heights

While Northwest Los Angeles Heights may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like San Antonio Zoo and Aquarium and Alamo.

Northwest Los Angeles Heights
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Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Northwest Side
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Shearer Hills - Ridgeview

While visiting Shearer Hills - Ridgeview, you might make a stop by sights like North Star Mall and Blessed Sacrament Catholic Church.

Shearer Hills - Ridgeview
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Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or The DoSeum while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

While visiting Tobin Hill, you might make a stop by sights like San Antonio River and Temple Beth-El.

Tobin Hill

Medical Center District Travel Guide

Choose two or more items and save on your trip: