Photo by Linda Cronan

Medical Center District Hotels, San Antonio

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

4220 Cheap Hotels in Medical Center District - Specials, Reviews, & Last Minute Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

2.5 star property
8.6 out of 10, Excellent, (2147)
"We had an issue with our first room but the front desk was very helpful in coordinating a room change. Our stay went great! Nice continental breakfast, just wish there was a little more variety for main entrees as we stayed for a week. Overall, it was a good stay!"
The price is AU$168
includes taxes & fees
23 Dec - 24 Dec
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 star property
9.0 out of 10, Wonderful, (712)
"Loud music from beer bar nearby till 2am. Hotel service and condition is great."
The price is AU$165
includes taxes & fees
29 Dec - 30 Dec
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

3.0 star property
9.2 out of 10, Wonderful, (1174)
"Its a very decent hotel for the price and very close to many restaurants and H-E-B."
The price is AU$189
includes taxes & fees
26 Dec - 27 Dec
Drury Inn & Suites San Antonio Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 star property
8.2 out of 10, Very good, (1006)
"The rooms and staff were very nice. The complementary cucumber and lemon water was very good as was the coffee in the morning. We stayed for the night with our future sailor. God bless our men and women of the armed forces. "
The price is AU$160
includes taxes & fees
26 Dec - 27 Dec
San Antonio Marriott Northwest Medical Center

SpringHill Suites by Marriott San Antonio Medical Center/NW

3.0 star property
8.8 out of 10, Excellent, (1002)
"Room was nice, clean, and spacious, but the bathroom was on the smaller side. Over all is was comfortable. Love the location easy to jump on the freeway. "
The price is AU$167
includes taxes & fees
30 Dec - 31 Dec
SpringHill Suites by Marriott San Antonio Medical Center/NW

Courtyard by Marriott Medical Center San Antonio

3.0 star property
8.6 out of 10, Excellent, (1002)
"My check in was at almost 2am. I was well received and taken care of quickly. Front desk staff was super friendly. "
The price is AU$167
includes taxes & fees
5 Jan - 6 Jan 2025
Courtyard by Marriott Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio

2.0 star property
7.2 out of 10, Good, (190)
"It was comfortable "
The price is AU$117
includes taxes & fees
24 Dec - 25 Dec
OYO Inn & Suites Medical Center San Antonio

Clarion Pointe near Medical Center

2.5 star property
7.0 out of 10, Good, (1491)
"El CUARTO esta muy limpio"
The price is AU$89
includes taxes & fees
5 Jan - 6 Jan 2025
Clarion Pointe near Medical Center

Atria Inn & Suites

2.0 star property
8.0 out of 10, Very good, (163)
"Easy to get to parking is a breeze check in fast I enjoyed my stay👍"
The price is AU$93
includes taxes & fees
23 Dec - 24 Dec
Atria Inn & Suites

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

3.0 star property
6.6 out of 10, (1007)
"Great service "
The price is AU$102
includes taxes & fees
5 Jan - 6 Jan 2025
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Studio 6 San Antonio, Tx - Northwest Medical Center

2.0 star property
7.2 out of 10, Good, (100)
"The facility is clean, accesible and the staff is kind and helpful. Near to the medical center. "
The price is AU$101
includes taxes & fees
23 Dec - 24 Dec
Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, TX - Medical Center

2.0 star property
6.6 out of 10, (642)
"O"
The price is AU$107
includes taxes & fees
23 Dec - 24 Dec
Studio 6 San Antonio, TX - Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center

2.0 star property
6.0 out of 10, (1002)
"I was happy with my stay here! I was able to relax and refresh for my stay here! I’m glad there are restaurants near by! Thank you for my guest experience!"
The price is AU$93
includes taxes & fees
23 Dec - 24 Dec
Motel 6 San Antonio, TX - Northwest Medical Center

Flex Studios

2.5 star property
5.8 out of 10, (436)
"Awesomeeee everything was great"
The price is AU$98
includes taxes & fees
23 Dec - 24 Dec
Flex Studios

La Quinta Inn and Suites by Wyndham Schertz-San Antonio-Selma

2.5 star property
8.0 out of 10, Very good, (934)
"Great"
The price is AU$145
includes taxes & fees
29 Dec - 30 Dec
La Quinta Inn and Suites by Wyndham Schertz-San Antonio-Selma

Best Western Plus Atrium Inn

2.5 star property
8.6 out of 10, Excellent, (972)
"Inside atrium pool and hot tub is clean and working and fabulous. Our room is clean and nice. We arrived early and were able to check in— check in guy was wonderful. Overnight check in guy was abrupt. We have two beds and we sleep cold. I asked for two extra blankets and he was adamant at only giving one — I guess I’ll sleep cold tonight since I will give my kids the one extra blanket. Cash only for little store in lobby if you need toiletries or a snack. Overall our stay is great and will...
The price is AU$166
includes taxes & fees
24 Dec - 25 Dec
Best Western Plus Atrium Inn

Super 8 by Wyndham Universal City

2.0 star property
6.4 out of 10, (1004)
"Found cockroachs in the bathroom. Door to the outside could not completely shut. I could still see outside. Almost every night it sounded like movers above us moving stuff and dropping it. My mother had a do not disturb sign on her door and yet house cleaning tried to come in almost everyday "
The price is AU$84
includes taxes & fees
29 Dec - 30 Dec
Super 8 by Wyndham Universal City

Best Western Plus San Antonio East Inn & Suites

2.5 star property
9.0 out of 10, Wonderful, (550)
"WIFI service was down most of our stay."
The price is AU$193
includes taxes & fees
5 Jan - 6 Jan 2025
Best Western Plus San Antonio East Inn & Suites

stayAPT Suites San Antonio-Randolph

2.5 star property
8.8 out of 10, Excellent, (262)
"The property manager was excellent. "
The price is AU$182
includes taxes & fees
26 Dec - 27 Dec
stayAPT Suites San Antonio-Randolph

WoodSpring Suites San Antonio North Live Oak I-35

2.5 star property
5.8 out of 10, (927)
"My stay was not bad at all. Easy check-in,room was like a mini apartment (had stove top,fridge,micro, etc.. Very quiet and really close to shopping centers and restaurants. "
The price is AU$86
includes taxes & fees
23 Dec - 24 Dec
WoodSpring Suites San Antonio North Live Oak I-35
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Medical Center District
Save an average of 15% on thousands of hotels when you're signed in

Frequently asked questions

What is Medical Center District like?

Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Are you looking for Medical Center District travel tips? Make sure that you visit USAA Corporate Office Headquarters and The San Antonio Art Institute while you're in the neighbourhood.

What's a favourite hotel to stay in Medical Center District?

Based on Expedia customer reviews, Drury Inn & Suites San Antonio Northwest Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and an indoor pool. Other favourite options in the area include SpringHill Suites by Marriott San Antonio Medical Center/NW and Fairfield Inn & Suites by Marriott San Antonio Medical Center.

How many hotels will I be able to find in Medical Center District?

Expedia has 124 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.

If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.

What can I see and do in this San Antonio neighbourhood?

A few attractions you might want to check out while you're in Medical Center District are USAA Corporate Office Headquarters and The San Antonio Art Institute. Wonderland of the Americas Mall and First Unitarian Universalist Church are also worth a visit when you're out sightseeing in San Antonio.