Photo by Pamela Ekundayo

Luxury Hotels & Resorts in Sant'Antioco

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Best Sant'Antioco Luxury Hotels

Beautiful view of the beach with palm trees

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Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

Are you searching for a luxury hotel for your Sant'Antioco holiday?
Let Expedia help you arrange your flight to Cagliari (CAG-Elmas) airport, and then choose from some places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a trip, so we make it easy to get what you want to make your stay special. If you want a posh hotel with fine dining, a spa or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Sant’Antioco has to offer. Sant’Antioco has some interesting things to see and do including Sant’Antioco Tourist Port and Maladroxia Beach, so you might want to take in the local sights during your visit.
What's the best luxury accommodation option in Sant'Antioco?
Lu’ Hotel Maladroxia is a 4-star hotel with a seasonal outdoor pool and a rooftop terrace, and it’s a popular choice for Expedia travellers looking for an elegant place to stay.
#### When to Visit Sant'Antioco\n
Planning for the weather is a good way to make your trip to Sant’Antioco relaxing and enjoyable, especially when you’re splurging. The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are February and January, with an average of 11°C. Average annual precipitation for Sant’Antioco is 477 mm.
What's there to see and do in Sant'Antioco?
Take in some sights and attractions while you’re in Sant’Antioco by visiting Sant’Antioco Tourist Port, Maladroxia Beach and Cala Sapone. If you have a bit of extra time while you’re in the area, you might want to check out Forte Su Pisu and Former Capo Sperone Signal Station.