Photo by Vivian Rennó

Search Santa Cruz hotels

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check Santa Cruz hotel prices

Tomorrow night
This weekend
Next weekend

Filter by

Guest rating
Guest rating
Property class

Top hotels and accommodation in Santa Cruz

Vik Chile
5.0 star property
9.2 out of 10, Wonderful, (99)
"Wine and cuisine are excellent. Room are all unique. "
The price is AU$1,043
includes taxes & fees
4 Dec - 5 Dec
Vik Chile
Hotel Cava Colchagua
4.0 star property
8.8 out of 10, Excellent, (132)
"OMG! This hotel was beyond my expectations. The grounds are beautiful, peaceful and relaxing. The rooms are perfect, I mean sleeping in an old wine barrel with a view of the vineyard - nothing tops that! The restaurant has a sumptuous breakfast and tasty lunch and dinner menu. Above all, their service is outstanding! I was able to arrange wine tours and transportation well before we arrived, all via WhatsApp. Their recommendations were perfect and we enjoyed every visit! I must make...
The price is AU$199
includes taxes & fees
5 Dec - 6 Dec
Hotel Cava Colchagua
Santa Cruz Plaza
4.0 star property
8.6 out of 10, Excellent, (287)
"Wow! We had a fantastic time at the Santa Cruz Plaza hotel. From the moment we arrived, the staff was extremely attentive and helpful. The property is beautiful, restaurant delicious, and it’s very conveniently located. Parking was easy and secure, too. A big thanks to the hotel staff for going above-and-beyond. Highly recommend! "
The price is AU$165
includes taxes & fees
26 Nov - 27 Nov
Santa Cruz Plaza
Noi Blend Colchagua
3.0 star property
9.0 out of 10, Wonderful, (113)
"Great stay in colchagua valley. The ideal place to be. Excellent location and staff. Facilities evoque me the old chilean houses at the country."
The price is AU$303
includes taxes & fees
28 Nov - 29 Nov
Noi Blend Colchagua
TerraViña
3.0 star property
9.4 out of 10, Exceptional, (185)
"Situated in the middle of wineries, away from the hustle bustle - TerraVina is a beautiful property with rooms with a balcony facing the Andes. There is a terrific winery just a 5 to 8 minute walk and three restaurants within 5 minutes, one located directly within the property. "
The price is AU$275
includes taxes & fees
29 Nov - 30 Nov
TerraViña
Hotel Vendimia Parador
3.0 star property
9.6 out of 10, Exceptional, (65)
"An interesting stay in a characterful building with beautiful garden and relaxing space to sit outside and enjoy a nice wine, produced by the owner, Mauricio. Breakfast is clearly a thing set in a very well dressed room. It is a cold buffet with plenty of fresh ingredients. "
The price is AU$190
includes taxes & fees
16 Dec - 17 Dec
Hotel Vendimia Parador
La Perla Hotel
3.5 star property
9.2 out of 10, Wonderful, (82)
"Friendly staff, Quiet and Safe. Clean rooms. Hot tub and pool not available when we were there (spring time)."
The price is AU$167
includes taxes & fees
28 Nov - 29 Nov
La Perla Hotel
Hotel Boutique Solaz Bella Vista de Colchagua
3.0 star property
9.4 out of 10, Exceptional, (93)
"."
The price is AU$141
includes taxes & fees
8 Dec - 9 Dec
Hotel Boutique Solaz Bella Vista de Colchagua
Hotel Boutique Vendimia Premium
3.5 star property
9.2 out of 10, Wonderful, (130)
"Good location. Antiques everywhere. Helpful staff. Nice to stay somewhere different. "
The price is AU$187
includes taxes & fees
20 Dec - 21 Dec
Hotel Boutique Vendimia Premium
Casa Calfu
3.0 star property
9.8 out of 10, Exceptional, (49)
"Lovely grounds, well appointed room, wonderful staff, lovely pool and abundant breakfast."
The price is AU$121
includes taxes & fees
28 Nov - 29 Nov
Casa Calfu
Hotel Viña La Playa
3.5 star property
8.2 out of 10, Very good, (17)
"Property has a lot of character, very clean, very pleasant and helpful staff. Great breakfast."
The price is AU$438
includes taxes & fees
22 Nov - 23 Nov
Hotel Viña La Playa
Parcela con tranque, sala de juegos, terraza,
The price is AU$255
includes taxes & fees
24 Nov - 25 Nov
Parcela con tranque, sala de juegos, terraza,
Casa Miranda
Casa Miranda
Hostal Vida 2000
2.5 star property
5.4 out of 10, (3)
"Simple clean place with wonderful hosts that were very accommodating. Breakfast was set up beautifully with plenty of food."
Hostal Vida 2000
Callihue de Colchagua Lodge
3.0 star property
Callihue de Colchagua Lodge
The ambush. Field and comfort
The ambush. Field and comfort
Hotel Hoja de Parra
3.0 star property
9.6 out of 10, Exceptional, (5)
"Ah-mazing! The innkeepers were so accommodating & hands on. Their personal touch made our stay extra special. We could not get over the farm fresh eggs (from the property) in the morning. They were seriously the best scrambled eggs I've ever had in my life. They were readily available for restaurant suggestions, which vineyards to check out, ice, wine glasses, whatever we needed to make our stay more comfortable. The 2 sweet dogs on property were just perfect to make you feel at home. We really...
Hotel Hoja de Parra
Apasos apartamentos
3.0 star property
9.6 out of 10, Exceptional, (4)
"Boa localização em local bastante tranquilo da pequena cidade. Limpeza muito boa. O frigobar deveria ser substituido por uma geladeira. É muito pequeno para uma família. A existência de ar condicionado apenas na sala é um outro ponto negativo. Faz muito calor no verão. Sem ar condicionado nos quartos, a estadia pode se tornar desconfortável."
Apasos apartamentos
cabaña en el campo, cerca de viñas, restaurant, a 2.7 km del centro.ciudad
10.0 out of 10, Exceptional, (1)
"Excellent. Great customer service, attentive host, flexible arrival"
cabaña en el campo, cerca de viñas, restaurant, a 2.7 km del centro.ciudad
Tierra y Vino
3.0 star property
Tierra y Vino
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Santa Cruz
Save an average of 15% on thousands of hotels when you're signed in
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

What's the best place for a stay in Santa Cruz?

Casa Calfu is a favourite property for Expedia customers. This B&B offers free breakfast and an outdoor pool. Reviews from our site also recommend La Perla Hotel and Hotel Boutique Vendimia Premium as top options for your visit. See all available top hotels, or vacation rentals in Santa Cruz.

What are some of the best holiday rentals that Santa Cruz has to offer?

Hosteria No me Olvides: This holiday home rental outside Santa Cruz offers a terrace and cable TV to help you feel comfortable in your new surroundings. Some other top choices in Santa Cruz are The ambush. Field and comfort and Casa Miranda. See all vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! The majority of hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

What's the best place to stay on a budget in Santa Cruz?

Based on our traveller reviews, Hostal Gomero is a top choice for a less expensive stay. Other good choices for your budget-friendly stay include Casa Suiza - Hostel and Hostal Casa Familia. View all budget hotels in Santa Cruz.

What's the best family accommodation in Santa Cruz?

Santa Cruz Plaza is a hotel with an outdoor pool and a free children's club, and it's a top choice on Expedia for families. Also, children of all ages will enjoy a visit to Colchagua Campo y Vino. Find more child-friendly accommodations in Santa Cruz.

What's the best hotel for a romantic getaway to Santa Cruz?

Hotel Cava Colchagua is a favourite hotel for couples, and features premium bedding and a full-service spa. Another good option for a romantic stay is TerraViña. See all romantic hotels in Santa Cruz.

What's the best dog-friendly accommodation option in Santa Cruz?

Hotel Vendimia Parador is a top hotel for people travelling with their pets, and offers an indoor pool and an outdoor pool for its human guests. Two other good options for you and your pet include Parcela con tranque, sala de juegos, terraza, and Cabañas Aisladas Tiny Colchagua. See more pet-friendly hotel accommodations in Santa Cruz.

What's the best luxury hotel in Santa Cruz?

Santa Cruz Plaza is a 4-star hotel with a full-service spa and free valet parking, and it's a popular choice for Expedia travellers looking for a pampered stay. Find more luxury hotels in Santa Cruz.

What's the best boutique accommodation in Santa Cruz?

Hotel Boutique Vendimia Premium is a favourite 3.5-star hotel with our travellers looking for stylish accommodation, and features 8 guestrooms, a poolside bar and a seasonal outdoor pool.

Where's the best place to stay if you want to visit the local casinos in Santa Cruz?

Hotel Boutique Vendimia Premium is a hotel featuring free WiFi and free parking, and it's a top choice near the casinos. See more casino hotels in Santa Cruz.

What are some accommodation options with pools in Santa Cruz?

Hotel Boutique Vendimia Premium is a top hotel with a children's pool, a seasonal outdoor pool and free WiFi. A couple of other options that offer an on-site pool include Hotel Vendimia Parador and Callihue de Colchagua Lodge. View all hotels with pools in Santa Cruz.

What is the best spa hotel in Santa Cruz?

Hotel Cava Colchagua is a top spa hotel featuring a vineyard, a bar, an outdoor pool and a restaurant. Treat yourself to a couples treatment, massage or the hot springs at the on-site spa. Other popular spa hotels in Santa Cruz include Santa Cruz Plaza and Hotel Boutique Solaz Bella Vista de Colchagua. See all spa hotels in Santa Cruz.

What's it like to stay in Santa Cruz?

Visitors to Santa Cruz will definitely enjoy the wineries, local tours and restaurants. Tourists can also enjoy so much more including its casinos. In Santa Cruz, there are 36 hotels and other accommodation options to choose from. Find out more about Santa Cruz.

What is there to see in Santa Cruz?

Wine tasting is a great activity, and Laura Hartwig Winery is one place to visit. A couple of additional sights to add to your itinerary are Casino Colchagua and Lapostolle Clos Apalta Winery. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.

What's the seasonal weather in Santa Cruz?

The hottest months are usually January and February, with an average temperature of 21°C, while the coldest months are July and August, with an average of 10°C. Average annual precipitation for Santa Cruz is 743 mm.