Santa Isabel Holiday Rentals

  • Plan, book, stay with confidence
  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Holiday Rentals in Santa Isabel

Private Over the Water Cabin on San Blas Island

2.0 star property
6.4 out of 10, (5)
"Communication was good and highly organized. We felt safe and didn’t need to lock up our bags or valuables at all times. Weather was rough (not their fault) so the stay was a challenge with super high winds and rain. The island was covered in trash nearly all the way around. Our cabin doors were off hinge and barely closed. The shower and sink were filthy and the toilet stained. The water smelled strongly of sulpher so we did not shower nor use it for anything other than a hand wash. Food was...
Private Over the Water Cabin on San Blas Island

Paradise Over the Water Cabins in San Blas

2.5 star property
6.0 out of 10, (1)
"29/22 i stay with my family for three nights and 4 days the beds are not comfortable and the fan doesn't work the bathroom need cleaning, the worst part is the sandflyies we got bitten all over our bodies, the owners can do better with proper new nets and fan and maybe spray the place, after the first night we want to leave so bad. The island is not so bad its peaceful and claim but after the bites we could take it we were prepared with bug spray but it was not enough for the bugs. The island...
Paradise Over the Water Cabins in San Blas

Catamaran experience in paradise

The price is AU$1,668
includes taxes & fees
28 Nov - 29 Nov
Catamaran experience in paradise

BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

10.0 out of 10, Exceptional, (29)
"A beautiful beachfront property with hammocks, snorkeling, kayaks and a lovely staff to prepare meals made this the ideal location for our family Christmas holiday."
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

The Jungle Lodge at Kalu Yala - Glamping

2.0 star property
2.0 out of 10, (1)
"The place is dirty and falling apart. The food is similar to that served in an elementary cafeteria. I was placed in a Teepee where the linens were dirty and wet towels were on the footstool. I was told to put my things there, and they would send someone to clean it. That never happened, so I moved myself. I was given no information about meal times, where things were, how to book tours etc. Stray dogs roam the property, and they clearly are not fed or cared for, mangey, and surround you at...
The Jungle Lodge at Kalu Yala - Glamping

The Camp at Kalu Yala

2.0 star property
The Camp at Kalu Yala

SHAULA 5 STARS LUXURY CHARTER SAN BLAS

SHAULA 5 STARS LUXURY CHARTER SAN BLAS

- SV La Francesca - san blas paradise on bord of private sailboat

- SV La Francesca - san blas paradise on bord of private sailboat

Experiences and Natural Life Sanblas

Experiences and Natural Life Sanblas

Stay on a Sailboat, San Blas

The price is AU$387
includes taxes & fees
26 Nov - 27 Nov
Stay on a Sailboat, San Blas

Enjoy San Blas - Wailidup Island

Enjoy San Blas - Wailidup Island

CATAMARAN LAGOON 52 FLY LUXURY 5 STARS IN SAN BLAS ALL INCLUSIVE

CATAMARAN LAGOON 52 FLY LUXURY 5 STARS IN SAN BLAS ALL INCLUSIVE

Breakfast, lunch, dinner, excursions, snorkeling and fishing equipment inclusive

10.0 out of 10, Exceptional, (6)
Breakfast, lunch, dinner, excursions, snorkeling and fishing equipment inclusive

Caribbean Paradise - Beachfront Getaway

The price is AU$761
includes taxes & fees
26 Nov - 27 Nov
Caribbean Paradise - Beachfront Getaway
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Santa Isabel
Save an average of 15% on thousands of hotels when you're signed in

Other types of properties in Santa Isabel you may be interested in

Private Ocean-Front Cabin with private bathroom on San Blas Island

2.0 star property
The price is AU$354
includes taxes & fees
28 Nov - 29 Nov
Private Ocean-Front Cabin with private bathroom on San Blas Island

San Blas Paradise Private Cabins on Shipwreck Island - meals included

2.0 star property
The price is AU$301
includes taxes & fees
28 Nov - 29 Nov
San Blas Paradise Private Cabins on Shipwreck Island - meals included

Private Over the Water Cabin on San Blas Island

2.0 star property
6.4 out of 10, (5)
"Communication was good and highly organized. We felt safe and didn’t need to lock up our bags or valuables at all times. Weather was rough (not their fault) so the stay was a challenge with super high winds and rain. The island was covered in trash nearly all the way around. Our cabin doors were off hinge and barely closed. The shower and sink were filthy and the toilet stained. The water smelled strongly of sulpher so we did not shower nor use it for anything other than a hand wash. Food was...
Private Over the Water Cabin on San Blas Island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

Are there holiday rentals in Santa Isabel?

Yes, there are holiday rentals close to the most popular sights in Santa Isabel, or you can select a more secluded option if you're looking for a relaxing stay. Santa Isabel is known for its parks.

What are some of the best holiday rentals that Santa Isabel has to offer?

Caribbean Beach Front Paradise: This holiday home rental outside of Santa Isabel is located on the beach, and has a patio, a garden and a BBQ to put you at ease in your new surroundings. It has 4 bedrooms, as well as a kitchen with a fridge, a stovetop and a microwave, so that you can cook with friends or family.

What’s there to see and do in Santa Isabel?

While exploring the area, visit the sights like Porvenir Museum, Chagres National Park and Museum.

What’s a holiday rental in Santa Isabel like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Santa Isabel. Holiday rentals feature extras like kitchens and laundry facilities so you'll have all the conveniences of home. If you're concerned about a clean environment, a holiday rental can offer a sense of safety away from public hotel lifts and busy lobbies while still allowing you the enjoyment of travel. You'll also get more space in a holiday rental than in a traditional hotel, which is another reason why a holiday rental is a popular option for a family getaway.