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Located 21.7 mi (34.8 km) from the heart of Santa Isabel, Private Ocean-Front Cabin with private bathroom on San Blas Island is a top choice for your stay, based on our traveller data. Two other choices for your visit to the area are San Blas Paradise Private Cabins on Shipwreck Island - meals included and Private Over the Water Cabin on San Blas Island. See all available top hotels, or vacation rentals in Santa Isabel.

Caribbean Paradise - Beachfront Getaway: This holiday home rental outside of Santa Isabel comes with air conditioning so that you can feel at home during your trip. See all vacation rentals in Santa Isabel.

Yes, the majority of hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Isabel.

Coral Lodge: Features free breakfast, an outdoor pool and free WiFi. Newly Built Over-the-Water cabins in San Blas Islands and Kalu Yala are a couple of other choices with an on-site pool.

Visitors can enjoy all that Santa Isabel has to offer, including its parks. There are 48 hotels and other accommodation options in the surrounding area. Find out more about Santa Isabel.

Places to visit in the wider area include Porvenir Museum, Chagres National Park and Museum. Take a look at what more there is to see and do in Expedia's Santa Isabel guide.

The hottest months are usually June and September, with an average temperature of 27°C, while the coldest months are February and March, with an average of 26°C. The rainiest months in Santa Isabel are October, August, July and November, with each month seeing an average of 310 mm of rainfall.