Search Santee hotels

  • Plan, book, stay with confidence

    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Check Santee hotel prices

Tonight
31 Dec - 1 Jan
Tomorrow night
1 Jan - 2 Jan
This weekend
3 Jan - 5 Jan
Next weekend
10 Jan - 12 Jan

Filter by

Guest rating
Guest rating
Property class

Top hotels and accommodation in Santee

Bear Historic Home
Smart TV, fireplace

Bear Historic Home

10.0 out of 10, Exceptional, (42)
"Very clean and welcoming, will definitely stay again."
Bear Historic Home
Spacious, Scenic Wagner Haven w/ River Access
Terrace/patio

Spacious, Scenic Wagner Haven w/ River Access

3.0 star property
8.0 out of 10, Very good, (1)
Spacious, Scenic Wagner Haven w/ River Access
Private updated hunting lodge/farmhouse
Miscellaneous

Private updated hunting lodge/farmhouse

10.0 out of 10, Exceptional, (1)
"Great place!!"
Private updated hunting lodge/farmhouse
Spacious, Scenic Wagner Haven w/ River Access
Terrace/patio

Spacious, Scenic Wagner Haven w/ River Access

10.0 out of 10, Exceptional, (25)
"We had an amazing time relaxing with family before school starts. The house had everything! It was very inviting and we felt right at home. Our kids loved the farm toys and the garage game room. Thank you for sharing your special space with us!"
Spacious, Scenic Wagner Haven w/ River Access
Overlooks Lewis & Clark Lake/Missouri River Basin-3 Hours Northwest of Omaha
Miscellaneous

Overlooks Lewis & Clark Lake/Missouri River Basin-3 Hours Northwest of Omaha

10.0 out of 10, Exceptional, (51)
"A wonderful view overlooking the Missouri River from the front porch and the front rooms of this home. My brother and I stayed here for 5 days. The kitchen/ dinning area and living room look out windows straight at the sunrise and the river. The home is absolutely a stay here if you’re in the area. The host is very nice and is easily accessible for your stay."
Overlooks Lewis & Clark Lake/Missouri River Basin-3 Hours Northwest of Omaha
The Copper Lodge in Springfield
Beach

The Copper Lodge in Springfield

10.0 out of 10, Exceptional, (20)
"Extremely clean. Nice and quiet. All the amenities you could want."
The Copper Lodge in Springfield
Cottage on Verdigris Creek
Property grounds

Cottage on Verdigris Creek

9.8 out of 10, Exceptional, (7)
"The creek was very nice. Screened in back porch had view of creek which was fun. We also hung out on front porch a lot. The birds sang a lot and trees were pretty. Our host was always available for questions"
Cottage on Verdigris Creek
Running Water Lodge with great amenities
Microwave, dishwasher, coffee/tea maker, cookware/dishes/utensils

Running Water Lodge with great amenities

9.0 out of 10, Wonderful, (2)
"Property is nicely located a short distance from Insanti Atv Park in Nebraska and Talsma Trail Park in South Dakota. Plenty of space for parking, lots of sleeping options and locals were friendly and helpful."
Running Water Lodge with great amenities
On the Bluff, Overlooking the River. Outdoorsman’s Paradise!
Private kitchen

On the Bluff, Overlooking the River. Outdoorsman’s Paradise!

On the Bluff, Overlooking the River. Outdoorsman’s Paradise!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Santee
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Frequently asked questions

Where is the best place for a stay in Santee?

Lewis and Clark Resort, located 16.8 mi (27 km) from the heart of Santee, is a top choice for your stay, based on our traveller data. 1916 renovated 8 bedroom, family-friendly home with great views is another good choice for your trip to the area. See all available top hotels, or vacation rentals in Santee.

What are some of the best holiday rentals that Santee has to offer?

Haven by the Lake: This holiday home rental outside of Santee offers a fireplace, a patio and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 5 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You can relax into your holiday with a garden and a selection of games. See all vacation rentals in Santee.

If I need to cancel my hotel reservation in Santee, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.

What are some hotels with pools in Santee?

Lewis and Clark Resort: Features free self-parking, an outdoor pool and free WiFi. View all hotels with pools in Santee.

What is staying in Santee like?

Those travelling to Santee will definitely enjoy the sights to see and things to do. There are 56 hotels and other accommodation options in the surrounding area. Find out more about Santee.

What is there to see in Santee?

A favourite place to visit is Lewis and Clark Lake. You'll also find Lewis and Clark Recreation Area and Niobrara State Park in the area. Take a look at what more there is to see and do in Expedia's Santee guide.

What's the seasonal weather in Santee?

The hottest months are usually July and August, with an average temperature of 22°C, while the coldest months are January and February, with an average of -3°C. The snowiest months in Santee are January, December, October and March, with each month seeing an average of 20 cm of snowfall.