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Top hotels and accommodation in Upstate South Carolina

Woodspring Suites Greenville Airport

2.5 star property
8.4 out of 10, Very good, (165)
"Great place to stay!!!"
The price is AU$141
includes taxes & fees
17 Aug - 18 Aug
Woodspring Suites Greenville Airport

Hampton Inn & Suites Greenville Airport, SC

2.5 star property
9.2 out of 10, Wonderful, (930)
"Great stay"
The price is AU$171
includes taxes & fees
5 Sept - 6 Sept
Hampton Inn & Suites Greenville Airport, SC

Postcard Cabins Lake Hartwell

2.0 star property
9.8 out of 10, Exceptional, (20)
"Clean and cute Wonderful getaway "
The price is AU$208
includes taxes & fees
17 Aug - 18 Aug
Postcard Cabins Lake Hartwell

The Shepherd Hotel Downtown Clemson

4.0 star property
9.8 out of 10, Exceptional, (659)
"Exceptional property and amenities, great for a quick trip or an extended stay. We highly recommend The Shepherd Hotel for any occasion."
The price is AU$306
includes taxes & fees
1 Sept - 2 Sept
The Shepherd Hotel Downtown Clemson

DoubleTree by Hilton Greenville Woodruff Road

3.0 star property
9.2 out of 10, Wonderful, (1001)
"Good Hotel "
The price is AU$200
includes taxes & fees
22 Aug - 23 Aug
DoubleTree by Hilton Greenville Woodruff Road

Hampton Inn Anderson/ Alliance Business Park

2.5 star property
9.2 out of 10, Wonderful, (776)
"Friendly staff, clean facility, decent amount of options for breakfast, kids loved the pool "
The price is AU$196
includes taxes & fees
22 Aug - 23 Aug
Hampton Inn Anderson/ Alliance Business Park

Best Western Plus Greenville I-385 Inn & Suites

2.5 star property
9.0 out of 10, Wonderful, (1351)
"Very nice affordable hotel accommodated to all my needs"
The price is AU$143
includes taxes & fees
17 Aug - 18 Aug
Best Western Plus Greenville I-385 Inn & Suites

Inn @ Clemson

2.5 star property
8.2 out of 10, Very good, (1006)
"The Inn is a great place to stay, staff is super friendly and it's in a great location 👍 "
The price is AU$201
includes taxes & fees
1 Sept - 2 Sept
Inn @ Clemson

Clemson University's James F. Martin Inn

3.0 star property
9.6 out of 10, Exceptional, (917)
"Terrific Place to stay"
The price is AU$253
includes taxes & fees
17 Aug - 18 Aug
Clemson University's James F. Martin Inn

Holiday Inn Express Gaffney by IHG

2.5 star property
8.6 out of 10, Excellent, (350)
"Everything great. Liked the choice of 4 different pillows on bed to choose from"
The price is AU$143
includes taxes & fees
21 Aug - 22 Aug
Holiday Inn Express Gaffney by IHG

Wingate by Wyndham - Greenville-Airport

2.5 star property
8.4 out of 10, Very good, (1001)
"Decent stay, would stay again. "
The price is AU$139
includes taxes & fees
16 Aug - 17 Aug
Wingate by Wyndham - Greenville-Airport

Hilton Greenville

3.5 star property
8.0 out of 10, Very good, (1003)
"Nice hotel. "
The price is AU$143
includes taxes & fees
17 Aug - 18 Aug
Hilton Greenville

Comfort Inn & Suites Clemson - University Area

2.5 star property
8.2 out of 10, Very good, (1004)
"Awesome place to stay"
The price is AU$173
includes taxes & fees
22 Aug - 23 Aug
Comfort Inn & Suites Clemson - University Area

Hyatt Place Greenville/Haywood

3.0 star property
7.8 out of 10, Good, (1001)
"Great hotel in an amazing area ! "
The price is AU$133
includes taxes & fees
22 Aug - 23 Aug
Hyatt Place Greenville/Haywood

Best Western Travelers Rest Greenville

2.5 star property
7.8 out of 10, Good, (1001)
"The staff was cheerful and helpful. "
The price is AU$149
includes taxes & fees
26 Aug - 27 Aug
Best Western Travelers Rest Greenville

Hotel Hartness

4.0 star property
9.8 out of 10, Exceptional, (575)
"Beautiful property and attentive staff. "
The price is AU$336
includes taxes & fees
17 Aug - 18 Aug
Hotel Hartness

Best Western Seneca-Clemson

2.5 star property
8.4 out of 10, Very good, (599)
"We liked the location. It was easy to explore Lake Keowee from here. The blackout window shades were nice too! The room was so humid that it even made the sheets feel damp. "
The price is AU$171
includes taxes & fees
14 Sept - 15 Sept
Best Western Seneca-Clemson

Country Inn & Suites by Radisson, Anderson, SC

2.5 star property
8.4 out of 10, Very good, (1000)
"It was a good place to stay good people "
The price is AU$180
includes taxes & fees
23 Aug - 24 Aug
Country Inn & Suites by Radisson, Anderson, SC

La Quinta Inn & Suites by Wyndham Greenville Haywood

3.0 star property
7.4 out of 10, Good, (1023)
"Great place loved it"
The price is AU$113
includes taxes & fees
17 Aug - 18 Aug
La Quinta Inn & Suites by Wyndham Greenville Haywood

The Inn at Patrick Square

3.5 star property
9.8 out of 10, Exceptional, (741)
"Quaint, boutique, location, excellent surrounfings. Would stay again"
The price is AU$255
includes taxes & fees
24 Aug - 25 Aug
The Inn at Patrick Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Upstate South Carolina, SC

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Stay near top Upstate South Carolina attractions

Learn more about Upstate South Carolina

Check out the local area in Upstate South Carolina—home to attractions like Discovery Island Water Park and Heritage Park.

Greenville - Spartanburg featuring a sunset, tranquil scenes and views
Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism

Top Upstate South Carolina Hotel Reviews