
Popular airlines from Orlando International Airport (MCO) to Alcoa - Knoxville Airport (TYS)
- American Airlines
American Airlines
- United
United
- Delta
Delta
- Frontier Airlines
Frontier Airlines
- Plan, book, fly with confidence
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Cheap Flights from Orlando (MCO) to Knoxville (TYS)
Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.










Origin airport | Orlando Intl. |
Destination airport | McGhee Tyson |
Return price | AU$382 |
Distance | 852 km |
Your quick guide to flights from Orlando to Knoxville
Pick up great flights from Orlando to Knoxville
With Expedia, you have your pick of flights a day with 20 airlines covering flights from Orlando to Knoxville. Whether you’re on a business trip, a family holiday or a luxury break, just enter your travel dates, hit search then check out your choice of flights. Select from return, one way or multi-city flights, and use the advance search tool if you want a direct or refundable flight. You can narrow your search to show you just your preferred cabin class and airline, too. It’s all easy. You can book direct flights from Orlando to Knoxville that take around hours.
Find cheap flights from Orlando to Knoxville
From the great flight deals with prices currently ranging from AU$383 to AU$533, you can choose to see the cheapest flights first. Generally, you can book the cheapest flights from Orlando to Knoxville around 4 to 6 weeks in advance. If your travel dates are flexible, try to avoid weekends and peak seasons – when you are more likely to grab the lowest prices. Even last minute, there are some impressive deals. The cheapest time to fly to Knoxville is normally in September.
Reasons to book your flight from Orlando to Knoxville with Expedia
Expedia makes it easy to find, book, and travel, with everything you need all in one place. When you enter your travel details, find fantastic deals just for you on flight tickets from Orlando to Knoxville across all the main airline carriers, so you can save time, dollars, and hassle finding the perfect flight. If you think your plans could change, choose refundable flights so any changes won’t cost you more. Book your flight to Knoxville right now and, if you join Expedia Rewards, you earn points this time and every time you travel with Expedia.
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Top Routes from Orlando
- Orlando to Newark Liberty Intl. Airport (MCO - EWR)
- Orlando to Mexico City (MCO - MEX)
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- Orlando to Amsterdam (MCO - AMS)
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- Orlando to Bogotá (MCO - BOG)
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