Luxury Hotels & Resorts in Megalochori

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Best Megalochori Luxury Hotels

Vedema, a Luxury Collection Resort, Santorini
5.0 star property
9.0 out of 10, Wonderful, (64)
" “Beautiful hotel, the views are spectacular, amazing staff, and wonderful food. We can’t wait to come back! Special thanks to Sam, our waiter during breakfast, and to Aris and Maria at the front desk.” "
Vedema, a Luxury Collection Resort, Santorini
Thermes Luxury Villas & Spa
9.6 out of 10, Exceptional, (55)
"Wonderful few days at Thermes. The rooms could do with a little TLC as looking a little dated, but the views by the pool are stunning. Proximity to Megalochori is a bonus, just 10min walk and the hotel 1min away has a fabulous restaurant with an incredible sunset view."
Thermes Luxury Villas & Spa
Athermi Suites - Adults Only
9.8 out of 10, Exceptional, (217)
"Great location, perfect sunset view, and delicious food "
Athermi Suites - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Beautiful view of the beach with palm trees

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Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.

Frequently asked questions

Are you looking for a luxury hotel for your Megalochori holiday?
Megalochori has some interesting things to see and do including Santorini Caldera and Gavalas Vineyard, so you might want to take in the local sights during your visit.
What's the best high-end hotel in Megalochori?
Vedema, a Luxury Collection Resort, Santorini is a luxury hotel with a private beach and 3 restaurants, and it’s a popular choice for Expedia travellers looking for an elegant place to stay. Another upscale option for your holiday is Nelya Suites.
How many luxury hotels are there in Megalochori?
Lie in the lap of luxury during your getaway to Megalochori in one of Expedia’s 8 luxury hotels.
#### When to Visit Megalochori\n
Planning for the weather is a good way to make your trip to Megalochori relaxing and enjoyable, especially when you’re splurging. The hottest months are usually August and July, with an average temperature of 24°C, while the coldest months are January and February, with an average of 15°C. Average annual precipitation for Megalochori is 333 mm.
What's there to see and do in Megalochori?
Enjoy all that Megalochori has to offer and visit Santorini Caldera, Gavalas Vineyard and Boutari Winery. If you have a bit of extra time while you’re in the area, you might want to check out Athinios Port and Perissa Beach.