Otay Mesa Holidays from AU$1,233
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to AU$703 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Top Holiday Package Deals in Otay Mesa
Price found within the past 48 hours. Click for updated prices.
Margaritaville Hotel San Diego Gaslamp Quarter
Downtown San Diego
Price was AU$2,383, price is now AU$1,612 per person
AU$1,612
per person
5 Nov - 10 Nov
found 1 day ago
Return flight included
Honolulu (HNL) to San Diego (SAN)
9/10 Wonderful! (1,038 reviews)
Rooms need some carpets or rugs
Reviewed on 27 Sept 2025
Estancia La Jolla Hotel & Spa
La Jolla Farms
Price was AU$2,484, price is now AU$1,861 per person
AU$1,861
per person
5 Nov - 10 Nov
found 1 day ago
Return flight included
Honolulu (HNL) to San Diego (SAN)
9/10 Wonderful! (275 reviews)
We just returned from this very lovely property. The plantings are gorgeous and the public spaces have plenty of comfortable seating spaces to relax. We especially enjoyed the evening in the lobby bar listening to a guitarist play gently in the background. The beds and rooms were comfortable. The housekeepers can be heard talking through the doors early in the morning. I shushed them! And I would not recommmend the very expensive, mediocre restaurant for dinner. Too many great and far less expensive choices around town. I do thank the front desk staff who listened to my issues and reported it to management. The front desk staff were all wonderful. The woman in the cafe was a little frosty. No idea why. But we enjoyed our stay and would recommend this lovely little gem to anyone.
Reviewed on 24 Sept 2025
Hampton Inn & Suites San Diego Seaworld
Point Loma
Price was AU$1,622, price is now AU$1,237 per person
AU$1,237
per person
5 Nov - 10 Nov
found 1 day ago
Return flight included
Honolulu (HNL) to San Diego (SAN)
8.6/10 Excellent! (61 reviews)
Booked on Expedia and upon arrival was notified it was $25 per day to park your vehicle on the property. There were no safe or convenient places to park other than on the property that was an unfortunate and unexpected.
But the facility was very nice! The rooms were immaculate. The breakfast service was also delicious as well as very clean throughout the entire facility, even in the hallways!
Reviewed on 27 Sept 2025
Our guide on where to stay in Otay Mesa
Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa
Downtown San Diego
2 out of top 10 points of interest in this area
4.5/5(100 area reviews)
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Our pick of the best Otay Mesa Hotel Deals
Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is AU$314 per night from 30 Sept to 1 Oct
AU$314
30 Sept - 1 Oct
includes taxes & fees
8.2/10 Very Good! (5,938 reviews)
"Room was great! Tile in bathroom was dirty. Sink did not function, front desk was notified. Otherwise a great stay, I'll be back"
Reviewed on 25 Sept 2025
Palihotel San Diego Gaslamp Quarter
830 Sixth Avenue, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is AU$193 per night from 23 Oct to 24 Oct
AU$193
23 Oct - 24 Oct
includes taxes & fees
8.6/10 Excellent! (1,831 reviews)
"Nice aesthetic and very friendly staff"
Reviewed on 25 Sept 2025
Bay Club Hotel & Marina
2131 Shelter Island Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is AU$209 per night from 29 Sept to 30 Sept
AU$209
29 Sept - 30 Sept
includes taxes & fees
9/10 Wonderful! (2,972 reviews)
"Great calm place"
Reviewed on 25 Sept 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover the most popular places to visit in Otay Mesa
San Diego Zoo
One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Mission Beach
A seaside village and a popular spot for holiday-makers for over a century, which today still retains its antique charm.
Activities
Crossing Borders: Tijuana Day Trip from San Diego
AU$141
per adult
96% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.