Serra Mesa Travel Guide

Tourist Guide


Popular places to visit

Activities


Our pick of the best Serra Mesa Hotel Deals

The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
The price is AU$298 per night from 25 Aug to 26 Aug
AU$298
25 Aug - 26 Aug
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (3,621 reviews)
Nice stay
"There is 5% fee associated when you eat out to make up for wage increases. That’s not really fair- especially with what they charge for rooms and food/beverages. Beds were okay. Service was slow in the firefly but food was good when it got to us. The bartender was great ( shaved head gentleman) and ..."

Reviewed on 10 Aug. 2025

The Dana on Mission Bay
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
Fully refundable
The price is AU$390 per night from 31 Aug to 1 Sept
AU$390
31 Aug - 1 Sept
includes taxes & fees
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
9/10 Wonderful! (2,777 reviews)
"Great service"

Reviewed on 13 Aug. 2025

Manchester Grand Hyatt San Diego
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is AU$308 per night from 3 Sept to 4 Sept
AU$308
3 Sept - 4 Sept
includes taxes & fees
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,824 reviews)
"Great location. Staff was very helpful"

Reviewed on 12 Aug. 2025

Wyndham San Diego Bayside
Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina

4 out of 5
1441 Quivira Rd, San Diego, CA
The price is AU$367 per night from 26 Aug to 27 Aug
AU$367
26 Aug - 27 Aug
includes taxes & fees
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.4/10 Very Good! (1,501 reviews)
"This hotel was an awesome family friendly resort with plenty of things for the kids and family to experience. We loved the ocean marina view from our suite, we got to walk out and see sea lions and try out kayaking. The only downside to this hotel is the parking is very limited and it is hard to ..."

Reviewed on 11 Aug. 2025

Hyatt Regency Mission Bay Spa and Marina
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our ...
8/10 Very Good! (1,943 reviews)
"Me"

Reviewed on 12 Aug. 2025

Handlery Hotel
Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown

4 out of 5
601 Pacific Hwy, San Diego, CA
The price is AU$373 per night from 1 Sept to 2 Sept
AU$373
1 Sept - 2 Sept
includes taxes & fees
Book a stay at this family-friendly hotel in San Diego. Enjoy free breakfast, room service, and a fitness center. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,341 reviews)
"👍"

Reviewed on 10 Aug. 2025

Embassy Suites by Hilton San Diego Bay Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Serra Mesa

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Mission Valley

4/5(29 area reviews)

Known for its stunning beaches and popular shops, there's plenty to explore in Mission Valley. Check out top attractions like Fashion Valley Mall and Snapdragon Stadium, and jump on the metro at Hazard Center Station or Mission Valley Center Station to see more of the city.

Mission Valley
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North Park

North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.

North Park
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Hillcrest

Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.

Hillcrest
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Del Cerro

While there might not be top attractions in Del Cerro, you can explore the larger area and discover places like Cal Coast Credit Union Open Air Theater and Viejas Arena.

Del Cerro
Old Town San Diego State Park which includes signage

Old Town San Diego

4.5/5(3 area reviews)

The abundant dining options and seaside views are top of the list for many visitors to Old Town San Diego. A stop by Old Town San Diego State Park or Whaley House Museum might round out your trip.

Old Town San Diego
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Mid-City

While you're in Mid-City, take in top sights like Cal Coast Credit Union Open Air Theater or Viejas Arena, and hop on the metro to see more of the city at SDSU Transit Center Station or Alvarado Station.

Mid-City

Serra Mesa Travel Guide

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